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Perioperative Mortality and Long-term Survival Following Live Kidney Donation

Perioperative Mortality and Long-term Survival Following Live Kidney Donation ORIGINAL CONTRIBUTION Perioperative Mortality and Long-term Survival Following Live Kidney Donation Dorry L. Segev, MD, PhD Context More than 6000 healthy US individuals every year undergo nephrectomy for the purposes of live donation; however, safety remains in question because lon- Abimereki D. Muzaale, MD, MPH gitudinal outcome studies have occurred at single centers with limited generalizability. Brian S. Caffo, PhD Objectives To study national trends in live kidney donor selection and outcome, to Shruti H. Mehta, PhD estimate short-term operative risk in various strata of live donors, and to compare long- Andrew L. Singer, MD, PhD term death rates with a matched cohort of nondonors who are as similar to the donor cohort as possible and as free as possible from contraindications to live donation. Sarah E. Taranto Design, Setting, and Participants Live donors were drawn from a mandated na- Maureen A. McBride, PhD tional registry of 80 347 live kidney donors in the United States between April 1, 1994, Robert A. Montgomery, MD, DPhil and March 31, 2009. Median (interquartile range) follow-up was 6.3 (3.2-9.8) years. A matched cohort was drawn from 9364 participants of the third National Health and Nutrition Examination Survey (NHANES III) after excluding those http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Perioperative Mortality and Long-term Survival Following Live Kidney Donation

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Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2010.237
pmid
20215610
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Perioperative Mortality and Long-term Survival Following Live Kidney Donation Dorry L. Segev, MD, PhD Context More than 6000 healthy US individuals every year undergo nephrectomy for the purposes of live donation; however, safety remains in question because lon- Abimereki D. Muzaale, MD, MPH gitudinal outcome studies have occurred at single centers with limited generalizability. Brian S. Caffo, PhD Objectives To study national trends in live kidney donor selection and outcome, to Shruti H. Mehta, PhD estimate short-term operative risk in various strata of live donors, and to compare long- Andrew L. Singer, MD, PhD term death rates with a matched cohort of nondonors who are as similar to the donor cohort as possible and as free as possible from contraindications to live donation. Sarah E. Taranto Design, Setting, and Participants Live donors were drawn from a mandated na- Maureen A. McBride, PhD tional registry of 80 347 live kidney donors in the United States between April 1, 1994, Robert A. Montgomery, MD, DPhil and March 31, 2009. Median (interquartile range) follow-up was 6.3 (3.2-9.8) years. A matched cohort was drawn from 9364 participants of the third National Health and Nutrition Examination Survey (NHANES III) after excluding those

Journal

JAMAAmerican Medical Association

Published: Mar 10, 2010

References