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Abstract A 2½-year-old child and his infant sibling developed febrile perianal cellulitis after the former had received a deltoid smallpox vaccination. Vaccinia virus was isolated from the perianal area in both cases, and histology of the lesions was compatible with cellulitis due to vaccinia virus. Staphlococcus aureus and group A streptococci were also recovered from the lesions. References 1. Weary, P.E., et al: Localized Accidental Vaccinia , Arch Derm 82:804-811 ( (Nov) ) 1960.Crossref 2. Lundström, R.: Complications of Smallpox Vaccination and Their Treatment With Vaccinia Immune Gamma Globulin , J Pediat 49:129-140 ( (July) ) 1956.Crossref 3. Berkowitz, J.: Accidental Vaccination About the Anus; Case Report , Amer J Surg 86:549-550 ( (Nov) ) 1953.Crossref 4. Lancefield, R.C.: A Serological Differentiation of Human and Other Groups of Hemolytic Streptococci , J Exp Med 57:571-595 ( (April) ) 1933.Crossref 5. Swift, H.F.; Wilson, A.T.; and Lancefield, R.C.: Typing Group A Hemolytic Streptococci by M Preciptin Reactions in Capillary Pipettes , J Exp Med 78:127-133 ( (Aug) ) 1943.Crossref 6. Amren, D.P.; Anderson, A.S.; and Wannamaker, L.W.: Perianal Cellulitis Associated With Group A Streptococci , Amer J Dis Child 112:546-552 ( (Dec) ) 1966.
Archives of Dermatology – American Medical Association
Published: Feb 1, 1969
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