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Pemphigus vs Acantholytic Herpetiform Dermatitis

Pemphigus vs Acantholytic Herpetiform Dermatitis Abstract To the Editor.— The report by Drs. DeMento and Grover in the Archives (107:883, 1973) poses a number of challenging questions, many of which remain to be answered. At this point, it appears that the best interests of the field of dermatology would be served by reporting as accurately as possible the basic findings in this (and hopefully in other comparable cases). The patient of Drs. DeMento and Grover appears to have some signs of pemphigus and some of dermatitis herpetiformis. Several possible diagnoses of the condition exist.1. This disease may be dermatitis herpetiformis (DH) as indicated in the aforementioned report. If this is so, it should be possible to detect the junctional deposits of IgA typical of DH in the patient's skin, since such deposits have been found in virtually all cases that have been examined adequately. Examination of two biopsy specimens studied in this laboratory failed to References 1. Tappeiner J, Holubar K: Fortschritte in der Differentialdiagnose klinisch-atypischer bullöser Dermatosen . Z Haut Geschl Krh 45:265-278, 1970. 2. Hebra F von, Kaposi M: On Diseases of the Skin . London, New Sydenham Society, 1880, vol 2. 3. Holubar K, et al: Immunofluorescence patterns in dermatitis herpetiformis . Br J Dermatol 85:505-510, 1971.Crossref 4. Shuster S, et al: Coeliac syndrome in dermatitis herpetiformis . Lancet 1:1101, 1968.Crossref 5. Andersen P, Hale WL: Immunofluorescent reactions with human sera on monkey esophagus , in Beutner EH, et al (eds): Immunopathology of the Skin . Stroudsburg, Pa, Dowden, Hutchinson & Ross, to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Pemphigus vs Acantholytic Herpetiform Dermatitis

Archives of Dermatology , Volume 109 (3) – Mar 1, 1974

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Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1974.01630030062020
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— The report by Drs. DeMento and Grover in the Archives (107:883, 1973) poses a number of challenging questions, many of which remain to be answered. At this point, it appears that the best interests of the field of dermatology would be served by reporting as accurately as possible the basic findings in this (and hopefully in other comparable cases). The patient of Drs. DeMento and Grover appears to have some signs of pemphigus and some of dermatitis herpetiformis. Several possible diagnoses of the condition exist.1. This disease may be dermatitis herpetiformis (DH) as indicated in the aforementioned report. If this is so, it should be possible to detect the junctional deposits of IgA typical of DH in the patient's skin, since such deposits have been found in virtually all cases that have been examined adequately. Examination of two biopsy specimens studied in this laboratory failed to References 1. Tappeiner J, Holubar K: Fortschritte in der Differentialdiagnose klinisch-atypischer bullöser Dermatosen . Z Haut Geschl Krh 45:265-278, 1970. 2. Hebra F von, Kaposi M: On Diseases of the Skin . London, New Sydenham Society, 1880, vol 2. 3. Holubar K, et al: Immunofluorescence patterns in dermatitis herpetiformis . Br J Dermatol 85:505-510, 1971.Crossref 4. Shuster S, et al: Coeliac syndrome in dermatitis herpetiformis . Lancet 1:1101, 1968.Crossref 5. Andersen P, Hale WL: Immunofluorescent reactions with human sera on monkey esophagus , in Beutner EH, et al (eds): Immunopathology of the Skin . Stroudsburg, Pa, Dowden, Hutchinson & Ross, to be published.

Journal

Archives of DermatologyAmerican Medical Association

Published: Mar 1, 1974

References