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Pediatricians' Recommendations for Antipyretic Agents With DTP Immunizations: A Survey of Current Practice

Pediatricians' Recommendations for Antipyretic Agents With DTP Immunizations: A Survey of Current... Abstract Sir.—Febrile and local reactions to diphtheria and tetanus toxoids and pertussis (DTP) vaccine are a frequent and major concern to parents and a source of discomfort to children. Among the most common reactions is fever, which occurs in 47% of immunized children.1 As a result, some pediatricians may empirically prescribe prophylactic antipyretic therapy at the time of vaccination. The extent of this practice has not been documented to our knowledge and, until recently, the benefit of such therapy has not been examined. To assess the frequency of this practice, we conducted a survey of community-based pediatricians to determine whether, and under what circumstances, they recommended prophylactic antipyretic therapy for children receiving DTP vaccine. The survey was performed before recently published reports documented the effectiveness of prophylactic acetaminophen therapy with DTP immunization.2,3 Despite the lack of studies documenting the usefulness of antipyretics, we anticipated that our survey would References 1. Cody CL, Baraff LJ, Cherry JD, Marcy SM, Manclar KCR. Nature and rates of adverse reactions associated with DTP and DT immunizations in infants and children . Pediatrics . 1981;68:650-660. 2. Ipp M, Gold R, Greenberg S, et al. Acetaminophen prophylaxis of adverse reactions following vaccination of infants with diphtheria-pertussis-tetanus toxoids-polio vaccine . Pediatr Infect Dis J . 1987;6:721-725.Crossref 3. Lewis K, Cherry JD, Sache MH, et al. The effect of prophylactic acetaminophen administration on reactions to DTP vaccination . AJDC . 1988;142:62-65. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Pediatricians' Recommendations for Antipyretic Agents With DTP Immunizations: A Survey of Current Practice

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1989 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1989.02150170011001
Publisher site
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Abstract

Abstract Sir.—Febrile and local reactions to diphtheria and tetanus toxoids and pertussis (DTP) vaccine are a frequent and major concern to parents and a source of discomfort to children. Among the most common reactions is fever, which occurs in 47% of immunized children.1 As a result, some pediatricians may empirically prescribe prophylactic antipyretic therapy at the time of vaccination. The extent of this practice has not been documented to our knowledge and, until recently, the benefit of such therapy has not been examined. To assess the frequency of this practice, we conducted a survey of community-based pediatricians to determine whether, and under what circumstances, they recommended prophylactic antipyretic therapy for children receiving DTP vaccine. The survey was performed before recently published reports documented the effectiveness of prophylactic acetaminophen therapy with DTP immunization.2,3 Despite the lack of studies documenting the usefulness of antipyretics, we anticipated that our survey would References 1. Cody CL, Baraff LJ, Cherry JD, Marcy SM, Manclar KCR. Nature and rates of adverse reactions associated with DTP and DT immunizations in infants and children . Pediatrics . 1981;68:650-660. 2. Ipp M, Gold R, Greenberg S, et al. Acetaminophen prophylaxis of adverse reactions following vaccination of infants with diphtheria-pertussis-tetanus toxoids-polio vaccine . Pediatr Infect Dis J . 1987;6:721-725.Crossref 3. Lewis K, Cherry JD, Sache MH, et al. The effect of prophylactic acetaminophen administration on reactions to DTP vaccination . AJDC . 1988;142:62-65.

Journal

American Journal of Diseases of Children – American Medical Association

Published: May 1, 1989

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