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Paul Ehrlich and His Impact on Dermatosyphilology

Paul Ehrlich and His Impact on Dermatosyphilology Abstract To name Paul Ehrlich in connection with dermatosyphilology at once calls up his most important practical achievement, the development and introduction of "606" (Salvarsan, or arsphenamine). This drug gave the syphilalogist the most potent weapon devised up to that time against any infectious disease. It put him into the enviable position of being able to arrest and often cure one of the great scourges of mankind. That the administration of old arsphenamine and even of neoarsphenamine and later drugs required a great deal of technical skill and specialized judgment also enhanced the standing of our specialty in the profession. Our knowledge of syphilis in its many ramifications widened the horizon of our endeavors by emphasizing the systemic implications, not only of this disease, but of other cutaneous disorders as well. The story of arsphenamine is common knowledge. As its practical usefulness is dwindling since the introduction References 1. No comprehensive biography of Paul Ehrlich has been written. There is only one book in the English language, authored by the master's faithful secretary, Miss Martha Marquardt.1 Several short German biographies have been published, the latest one by Greiling.2 Ehrlich's scientific achievements were evaluated by 37 of his friends and pupils on the occasion of his 60th birthday.3 A complete edition of his publications, with English translations of the more important articles and a complete bibliography, will shortly be available.4 2. References 11, 12, and 13. 3. Marquardt, M.: Paul Ehrlich , New York, Henry Schuman, Inc., 1951. 4. Greiling, W.: Paul Ehrlich, Leben und Werk, Düsseldorf , Econ Verlag, 1954. 5. Apolant, H., and others: Paul Ehrlich: Eine Darstellung seines wissenschaftlichen Wirkens, Festschrift zum 60. Geburtstage des Forschers (14. März 1914) , Jena, Gustav Fischer, 1914. 6. Ehrlich, P.: The Collected Papers of Paul Ehrlich , Vol. I-IV, London, Pergamon Press, Ltd., to be published. 7. Ehrlich, P.: Über Partialfunktionen der Zelle, Nobel Lecture , delivered in Stockholm, (Dec. 11) , 1908 8. reprinted, Internat. Arch. Allergy 5:67-86, 1954.Crossref 9. Ehrlich, P.: Herter Lectures I-III , Boston M. & S. J. 150:443-450 ( (April 28) ) 1904. 10. Professor Ehrlich's Visit to Chicago, editorial , J. A. M. A. 42:772-773 ( (March 19) ) 1904. 11. The Visit of Prof. Paul Ehrlich, editorial , Boston M. & S. J. 150:356-357 ( (March 31) ) 1904. 12. Amberg, E.: Professor Paul Ehrlich's Visit in Detroit , Wayne County M. Soc. Weekly Bull. 22: (No. (18) ) 6 and 27 (Dec. 30) 1930. 13. George Lutz Retires , Univ. Michigan M. Bull. 19:160-162 ( (June) ) 1953. 14. Aron, H. C. S.: Paul Ehrlich: His Contributions to Medicine , J. A. M. A. 154:969-972 ( (March 20) ) 1954. 15. Schnitzer, R. J.; Grunberg, E., and other: Paul Ehrlich Centennial , Ann. New York Acad. Sc. 59:141-276 ( (Sept. 23) ) 1954. 16. Pinkus, H.: In Commemoration of the 100th Anniversary of the Birth of Paul Ehrlich , Am. J. Clin. Path. 24:751-754 ( (July) ) 1954. 17. Stühmer, A.: Paul Ehrlich: Persönlichkeit und Werk in der Sicht des Dermatologen , Internat. Arch. Allergy 5:87-97, 1954. 18. Jorpes, E., and others: An Autoradiographic Study on the Uptake of S35 Labeled Sodium Sulphate in the Mast Cells , Acta Haemat. 9:273-276 ( (May) ) 1953. 19. Asboe-Hansen, G.: Autoradiography of Mast - . Cells in Experimental Skin Tumors of Mice Injected with Radioactive Sulfur (S35) , Cancer Res. 13:587-589 ( (Aug.) ) 1953. 20. Pinkus, F.: Die lymphatische Leukaemie , in Nothnagel, C. W. H, editor: Spezielle Pathologie und Therapy , Wien, Alfred Hoelder, 1901, Vol. 8, Part 1, Issue (3) , pp. 3-107. 21. Ehrlich, P.: Die Anaemie , Wien, Alfred Hoelder, 1909, Ed. 2, p. 3 of Preface. 22. Kabat, E. A.: Purification of Human Antidextran , Science 120:782 ( (Nov. 12) ) 1954. 23. The Collected Papers of Adolf Meyer, (Baltimore, Johns Hopkins Press, 1950-51), book review , J. A. M. A. 147:356 ( (Sept. 22) ) 1951. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

Paul Ehrlich and His Impact on Dermatosyphilology

A.M.A. Archives of Dermatology , Volume 72 (2) – Aug 1, 1955

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Publisher
American Medical Association
Copyright
Copyright © 1955 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1955.03730320015002
Publisher site
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Abstract

Abstract To name Paul Ehrlich in connection with dermatosyphilology at once calls up his most important practical achievement, the development and introduction of "606" (Salvarsan, or arsphenamine). This drug gave the syphilalogist the most potent weapon devised up to that time against any infectious disease. It put him into the enviable position of being able to arrest and often cure one of the great scourges of mankind. That the administration of old arsphenamine and even of neoarsphenamine and later drugs required a great deal of technical skill and specialized judgment also enhanced the standing of our specialty in the profession. Our knowledge of syphilis in its many ramifications widened the horizon of our endeavors by emphasizing the systemic implications, not only of this disease, but of other cutaneous disorders as well. The story of arsphenamine is common knowledge. As its practical usefulness is dwindling since the introduction References 1. No comprehensive biography of Paul Ehrlich has been written. There is only one book in the English language, authored by the master's faithful secretary, Miss Martha Marquardt.1 Several short German biographies have been published, the latest one by Greiling.2 Ehrlich's scientific achievements were evaluated by 37 of his friends and pupils on the occasion of his 60th birthday.3 A complete edition of his publications, with English translations of the more important articles and a complete bibliography, will shortly be available.4 2. References 11, 12, and 13. 3. Marquardt, M.: Paul Ehrlich , New York, Henry Schuman, Inc., 1951. 4. Greiling, W.: Paul Ehrlich, Leben und Werk, Düsseldorf , Econ Verlag, 1954. 5. Apolant, H., and others: Paul Ehrlich: Eine Darstellung seines wissenschaftlichen Wirkens, Festschrift zum 60. Geburtstage des Forschers (14. März 1914) , Jena, Gustav Fischer, 1914. 6. Ehrlich, P.: The Collected Papers of Paul Ehrlich , Vol. I-IV, London, Pergamon Press, Ltd., to be published. 7. Ehrlich, P.: Über Partialfunktionen der Zelle, Nobel Lecture , delivered in Stockholm, (Dec. 11) , 1908 8. reprinted, Internat. Arch. Allergy 5:67-86, 1954.Crossref 9. Ehrlich, P.: Herter Lectures I-III , Boston M. & S. J. 150:443-450 ( (April 28) ) 1904. 10. Professor Ehrlich's Visit to Chicago, editorial , J. A. M. A. 42:772-773 ( (March 19) ) 1904. 11. The Visit of Prof. Paul Ehrlich, editorial , Boston M. & S. J. 150:356-357 ( (March 31) ) 1904. 12. Amberg, E.: Professor Paul Ehrlich's Visit in Detroit , Wayne County M. Soc. Weekly Bull. 22: (No. (18) ) 6 and 27 (Dec. 30) 1930. 13. George Lutz Retires , Univ. Michigan M. Bull. 19:160-162 ( (June) ) 1953. 14. Aron, H. C. S.: Paul Ehrlich: His Contributions to Medicine , J. A. M. A. 154:969-972 ( (March 20) ) 1954. 15. Schnitzer, R. J.; Grunberg, E., and other: Paul Ehrlich Centennial , Ann. New York Acad. Sc. 59:141-276 ( (Sept. 23) ) 1954. 16. Pinkus, H.: In Commemoration of the 100th Anniversary of the Birth of Paul Ehrlich , Am. J. Clin. Path. 24:751-754 ( (July) ) 1954. 17. Stühmer, A.: Paul Ehrlich: Persönlichkeit und Werk in der Sicht des Dermatologen , Internat. Arch. Allergy 5:87-97, 1954. 18. Jorpes, E., and others: An Autoradiographic Study on the Uptake of S35 Labeled Sodium Sulphate in the Mast Cells , Acta Haemat. 9:273-276 ( (May) ) 1953. 19. Asboe-Hansen, G.: Autoradiography of Mast - . Cells in Experimental Skin Tumors of Mice Injected with Radioactive Sulfur (S35) , Cancer Res. 13:587-589 ( (Aug.) ) 1953. 20. Pinkus, F.: Die lymphatische Leukaemie , in Nothnagel, C. W. H, editor: Spezielle Pathologie und Therapy , Wien, Alfred Hoelder, 1901, Vol. 8, Part 1, Issue (3) , pp. 3-107. 21. Ehrlich, P.: Die Anaemie , Wien, Alfred Hoelder, 1909, Ed. 2, p. 3 of Preface. 22. Kabat, E. A.: Purification of Human Antidextran , Science 120:782 ( (Nov. 12) ) 1954. 23. The Collected Papers of Adolf Meyer, (Baltimore, Johns Hopkins Press, 1950-51), book review , J. A. M. A. 147:356 ( (Sept. 22) ) 1951.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: Aug 1, 1955

References