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Patterns of Atopic Eczema Disease Activity From Birth Through Midlife in 2 British Birth Cohorts

Patterns of Atopic Eczema Disease Activity From Birth Through Midlife in 2 British Birth Cohorts Key PointsQuestionAre there patterns of atopic eczema activity that continue into adulthood? FindingsAmong 30 905 participants evaluated from birth into midlife, 4 patterns of activity for atopic eczema were identified across ages: high probability, decreasing, increasing, and low probability. Early life factors did not differentiate the high from the decreasing subtype, and the subtype with increasing probability of activity had the highest risk of poor self-reported health in midlife. MeaningThe probability of atopic eczema remains high into adulthood for a subgroup of patients but decreases for others; a newly identified subgroup with increasing probability of activity in adulthood warrants additional research. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

Patterns of Atopic Eczema Disease Activity From Birth Through Midlife in 2 British Birth Cohorts

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Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/jamadermatol.2021.2489
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionAre there patterns of atopic eczema activity that continue into adulthood? FindingsAmong 30 905 participants evaluated from birth into midlife, 4 patterns of activity for atopic eczema were identified across ages: high probability, decreasing, increasing, and low probability. Early life factors did not differentiate the high from the decreasing subtype, and the subtype with increasing probability of activity had the highest risk of poor self-reported health in midlife. MeaningThe probability of atopic eczema remains high into adulthood for a subgroup of patients but decreases for others; a newly identified subgroup with increasing probability of activity in adulthood warrants additional research.

Journal

JAMA DermatologyAmerican Medical Association

Published: Oct 1, 2021

References