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Pathological Cases of the Month

Pathological Cases of the Month Abstract A 19-year-old right-handed man suffered from seizures characterized by staring that lasted about 10 minutes and began at age 13 years. These seizures were initially well controlled with medications but became refractory, occurring three to five times per week. A computed tomographic scan at age 13 years revealed a densely calcified mass in the right frontal lobe with no detectable contrast enhancement. A second scan at age 18 years showed no significant change in the right frontal lobe mass. T1-weighted magnetic resonance imaging at that time showed an inhomogeneous mass in the right frontal lobe with a broad-based surface but no dural attachment (Fig 1). Foci of intense enhancement were seen on contrast magnetic resonance image. In T2-weighted images, low-signal areas corresponded to the calcification seen on computed tomography. Angiography showed evidence of an avascular mass; abnormal vessels and tumor blush were absent. Electroencephalography revealed an References 1. Halper J, Scheithauer BW, Okazaki H, Law ER. Meningioangiomatosis: a report of six cases with special reference to the occurrence of neurofibrillary tangles . J Neuropathol Exp Neurol . 1986;45:426-446.Crossref 2. Kasantikul V, Brown WJ. Meningioangiomatosis in the absence of von Recklinghausen's disease . Surg Neurol . 1981;15:71-75.Crossref 3. Paulus W, Peiffer J, Roggendorf W, Schuppan D. Meningioangiomatosis . Pathol Res Pract . 1989;184:446-452.Crossref 4. Ogilvy CS, Chapman PH, Gray M, de la Monte SM. Meningioangiomatosis in a patient without von Recklinghausen's disease . J Neurosurg . 1989;70:483-485.Crossref 5. Kunishio K, Yamamoto Y, Sunani N, et al. Histopathologic investigation of a case of meningioangiomatosis not associated with von Recklinghausen's disease . Surg Neurol . 1987;27:575-579.Crossref 6. Kuzneicky R, Melanson D, Robitaille Y, Oliver A. Magnetic resonance imaging of meningioangiomatosis . Can J Neurol Sci . 1988;15:161-164. 7. Liu SS, Johnson PC, Sonntug VKH. Meningioangiomatosis: a case report . Surg Neurol . 1989;31:376-380.Crossref 8. Sakaki S, Nakagawa K, Nakamura K, Takeda S. Meningioangiomatosis not associated with von Recklinhausen's disease . Neurosurgery . 1987:20: 797-801.Crossref 9. Rhodes RH, Davis RL. An unusual fibro-osseous component in intracranial lesions . Hum Pathol . 1978;9:309-319.Crossref 10. Jun C, Burdick B. An unusual fibro-osseous of the brain . J Neurosurg . 1984;60:1308-1311.Crossref 11. Wilson N, Kaufman MA, Bodansky SM. An unusual intracerebral connective tissue mass . J Neuropathol Exp Neurol . 1977;36:373-378.Crossref 12. Bassie P, Nuzum F. Report of a case of central and peripheral neurofibromatosis . J Nerv Ment Dis . 1915;42:785-796.Crossref 13. Worster-Drought C, Dickson WEC, McMenemey WH. Multiple meningeal and perineural tumors with analogous changes in the glia and ependyma . Brain . 1937;60:85-117.Crossref 14. Hozak J. Une angioneuromatose meningo-encephalage diffuse . Rev Neurol (Paris) . 1953;89:222-236. 15. Whiting DM, Awad IA, Miles J, Chou SM, Luders H. Intractable complex partial seizures associated with occult temporal lobe encephalocele and meningioangiomatosis . Surg Neurol . 1990;34:318-332.Crossref 16. Russell DS, Rubinstein LJ. Pathology of Tumors of the Central Nervous System . 5th ed. Baltimore, Md: William & Wilkins; 1989. 17. Partington CR, Graves VB, Hegstrand LR. Meningioangiomatosis . AJNR Am J Neuroradiol . 1991;12:549-552. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1993 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1993.02160330099030
Publisher site
See Article on Publisher Site

Abstract

Abstract A 19-year-old right-handed man suffered from seizures characterized by staring that lasted about 10 minutes and began at age 13 years. These seizures were initially well controlled with medications but became refractory, occurring three to five times per week. A computed tomographic scan at age 13 years revealed a densely calcified mass in the right frontal lobe with no detectable contrast enhancement. A second scan at age 18 years showed no significant change in the right frontal lobe mass. T1-weighted magnetic resonance imaging at that time showed an inhomogeneous mass in the right frontal lobe with a broad-based surface but no dural attachment (Fig 1). Foci of intense enhancement were seen on contrast magnetic resonance image. In T2-weighted images, low-signal areas corresponded to the calcification seen on computed tomography. Angiography showed evidence of an avascular mass; abnormal vessels and tumor blush were absent. Electroencephalography revealed an References 1. Halper J, Scheithauer BW, Okazaki H, Law ER. Meningioangiomatosis: a report of six cases with special reference to the occurrence of neurofibrillary tangles . J Neuropathol Exp Neurol . 1986;45:426-446.Crossref 2. Kasantikul V, Brown WJ. Meningioangiomatosis in the absence of von Recklinghausen's disease . Surg Neurol . 1981;15:71-75.Crossref 3. Paulus W, Peiffer J, Roggendorf W, Schuppan D. Meningioangiomatosis . Pathol Res Pract . 1989;184:446-452.Crossref 4. Ogilvy CS, Chapman PH, Gray M, de la Monte SM. Meningioangiomatosis in a patient without von Recklinghausen's disease . J Neurosurg . 1989;70:483-485.Crossref 5. Kunishio K, Yamamoto Y, Sunani N, et al. Histopathologic investigation of a case of meningioangiomatosis not associated with von Recklinghausen's disease . Surg Neurol . 1987;27:575-579.Crossref 6. Kuzneicky R, Melanson D, Robitaille Y, Oliver A. Magnetic resonance imaging of meningioangiomatosis . Can J Neurol Sci . 1988;15:161-164. 7. Liu SS, Johnson PC, Sonntug VKH. Meningioangiomatosis: a case report . Surg Neurol . 1989;31:376-380.Crossref 8. Sakaki S, Nakagawa K, Nakamura K, Takeda S. Meningioangiomatosis not associated with von Recklinhausen's disease . Neurosurgery . 1987:20: 797-801.Crossref 9. Rhodes RH, Davis RL. An unusual fibro-osseous component in intracranial lesions . Hum Pathol . 1978;9:309-319.Crossref 10. Jun C, Burdick B. An unusual fibro-osseous of the brain . J Neurosurg . 1984;60:1308-1311.Crossref 11. Wilson N, Kaufman MA, Bodansky SM. An unusual intracerebral connective tissue mass . J Neuropathol Exp Neurol . 1977;36:373-378.Crossref 12. Bassie P, Nuzum F. Report of a case of central and peripheral neurofibromatosis . J Nerv Ment Dis . 1915;42:785-796.Crossref 13. Worster-Drought C, Dickson WEC, McMenemey WH. Multiple meningeal and perineural tumors with analogous changes in the glia and ependyma . Brain . 1937;60:85-117.Crossref 14. Hozak J. Une angioneuromatose meningo-encephalage diffuse . Rev Neurol (Paris) . 1953;89:222-236. 15. Whiting DM, Awad IA, Miles J, Chou SM, Luders H. Intractable complex partial seizures associated with occult temporal lobe encephalocele and meningioangiomatosis . Surg Neurol . 1990;34:318-332.Crossref 16. Russell DS, Rubinstein LJ. Pathology of Tumors of the Central Nervous System . 5th ed. Baltimore, Md: William & Wilkins; 1989. 17. Partington CR, Graves VB, Hegstrand LR. Meningioangiomatosis . AJNR Am J Neuroradiol . 1991;12:549-552.

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Sep 1, 1993

References