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PASSIVE IMMUNITY IN INFANTS AND THEIR RESPONSE TO DIPHTHERIA TOXOID

PASSIVE IMMUNITY IN INFANTS AND THEIR RESPONSE TO DIPHTHERIA TOXOID The most favorable age at which vaccination against diphtheria should be carried out is a matter of considerable disagreement. It is desirable to obtain immunity at as early an age as possible. In private practice, pediatricians have been recommending such active immunization at the end of the first year. Recently, vigorous public health programs have been advancing the age to 6 months. There are two factors that enter into the question of the advisability of vaccination at this age: (1) the fact that young individuals are poor formers of antitoxin and (2) the fact that a considerable proportion of infants still retain their passive immunity at this age. In a recent publication, one of us1 has shown that infants under 6 months of age respond to vaccination less favorably than those over this age, in that the percentage immunized is smaller; and, even when immunity is obtained, it is http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

PASSIVE IMMUNITY IN INFANTS AND THEIR RESPONSE TO DIPHTHERIA TOXOID

JAMA , Volume 105 (5) – Aug 3, 1935

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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1935 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1935.02760310015004
Publisher site
See Article on Publisher Site

Abstract

The most favorable age at which vaccination against diphtheria should be carried out is a matter of considerable disagreement. It is desirable to obtain immunity at as early an age as possible. In private practice, pediatricians have been recommending such active immunization at the end of the first year. Recently, vigorous public health programs have been advancing the age to 6 months. There are two factors that enter into the question of the advisability of vaccination at this age: (1) the fact that young individuals are poor formers of antitoxin and (2) the fact that a considerable proportion of infants still retain their passive immunity at this age. In a recent publication, one of us1 has shown that infants under 6 months of age respond to vaccination less favorably than those over this age, in that the percentage immunized is smaller; and, even when immunity is obtained, it is

Journal

JAMAAmerican Medical Association

Published: Aug 3, 1935

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