Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Parathyroidectomy in Elderly Individuals With Primary Hyperparathyroidism

Parathyroidectomy in Elderly Individuals With Primary Hyperparathyroidism Opinion EDITORIAL Parathyroidectomy in Elderly Individuals With Primary Hyperparathyroidism To Operate or Not to Operate Anand R. Habib, MD, MPhil; Mitchell H. Katz, MD nificant regardless of sex, frailty severity, history of osteoporo- Primary hyperparathyroidism (PHPT) is the most common cause of chronic hypercalcemia. With advancing age, the in- sis, or prior pharmacologic therapy for osteoporosis, whether an cidence increases for both sexes, reaching 196 per 100 000 per- individual met other operative recommendations or had long- son-years for women and 95 per 100 000 person-years for term oral corticosteroid use. 1 4 men by 70 to 79 years of age. The valuable findings by Seib and colleagues were not Approximately 80% of indi- without limitations. First, as with other administrative data Related article page 10 viduals with PHPT initially analyses, the authors assumed reliable coding of the diagno- lack symptoms such as nephrolithiasis, kidney dysfunction, ses and procedures by clinicians. Additionally, being a retro- gastrointestinal upset, and neuropsychiatric effects. How- spective cohort analysis, the possibility of residual confound- ever, even among asymptomatic individuals, PHPT acceler- ing remains. Second, the authors categorized individuals with ates bone turnover, predisposing them to osteoporosis and parathyroidectomy more than 1 year after diagnosis http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Parathyroidectomy in Elderly Individuals With Primary Hyperparathyroidism

JAMA Internal Medicine , Volume 182 (1) – Jan 29, 2022

Loading next page...
 
/lp/american-medical-association/parathyroidectomy-in-elderly-individuals-with-primary-5ow0Ya8wQH
Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/jamainternmed.2021.6816
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Parathyroidectomy in Elderly Individuals With Primary Hyperparathyroidism To Operate or Not to Operate Anand R. Habib, MD, MPhil; Mitchell H. Katz, MD nificant regardless of sex, frailty severity, history of osteoporo- Primary hyperparathyroidism (PHPT) is the most common cause of chronic hypercalcemia. With advancing age, the in- sis, or prior pharmacologic therapy for osteoporosis, whether an cidence increases for both sexes, reaching 196 per 100 000 per- individual met other operative recommendations or had long- son-years for women and 95 per 100 000 person-years for term oral corticosteroid use. 1 4 men by 70 to 79 years of age. The valuable findings by Seib and colleagues were not Approximately 80% of indi- without limitations. First, as with other administrative data Related article page 10 viduals with PHPT initially analyses, the authors assumed reliable coding of the diagno- lack symptoms such as nephrolithiasis, kidney dysfunction, ses and procedures by clinicians. Additionally, being a retro- gastrointestinal upset, and neuropsychiatric effects. How- spective cohort analysis, the possibility of residual confound- ever, even among asymptomatic individuals, PHPT acceler- ing remains. Second, the authors categorized individuals with ates bone turnover, predisposing them to osteoporosis and parathyroidectomy more than 1 year after diagnosis

Journal

JAMA Internal MedicineAmerican Medical Association

Published: Jan 29, 2022

References