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Paranoid Psychosis With Sulindac

Paranoid Psychosis With Sulindac To the Editor.— Sulindac (Clinoril) is a recently marketed, nonsteroidal anti-inflammatory agent that is chemically related to indomethacin. We report a case of sulindac-associated psychosis. Report of a Case.— A 53-year-old, married man with a previously stable personality was well until ten days before admission to the hospital. After his first golf game of the spring, he noted painful swelling in both hands and, shortly thereafter, pain in the right knee. Roentgenograms of the hands and knee were normal. The pain and swelling persisted, and two days before admission he began receiving sulindac, 150 mg twice daily. Four hours after the first dose, the patient exhibited bizarre behavior, characterized by obsessive talking about his "inside information" concerning the Bermuda Triangle. The number "3" also held special significance for him. He demonstrated paranoid behavior, becoming distrustful of family members and being physically combative. Results of the physical examination disclosed no abnormalities http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Paranoid Psychosis With Sulindac

Kruis, Richard; Barger, Robert
JAMA , Volume 243 (14) – Apr 11, 1980
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Paranoid Psychosis With Sulindac

Abstract



To the Editor.—
Sulindac (Clinoril) is a recently marketed, nonsteroidal anti-inflammatory agent that is chemically related to indomethacin. We report a case of sulindac-associated psychosis.


Report of a Case.—
A 53-year-old, married man with a previously stable personality was well until ten days before admission to the hospital. After his first golf game of the spring, he noted painful swelling in both hands and, shortly thereafter, pain in the right knee. Roentgenograms of...
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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1980 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1980.03300400010004
Publisher site
See Article on Publisher Site

Abstract

To the Editor.— Sulindac (Clinoril) is a recently marketed, nonsteroidal anti-inflammatory agent that is chemically related to indomethacin. We report a case of sulindac-associated psychosis. Report of a Case.— A 53-year-old, married man with a previously stable personality was well until ten days before admission to the hospital. After his first golf game of the spring, he noted painful swelling in both hands and, shortly thereafter, pain in the right knee. Roentgenograms of the hands and knee were normal. The pain and swelling persisted, and two days before admission he began receiving sulindac, 150 mg twice daily. Four hours after the first dose, the patient exhibited bizarre behavior, characterized by obsessive talking about his "inside information" concerning the Bermuda Triangle. The number "3" also held special significance for him. He demonstrated paranoid behavior, becoming distrustful of family members and being physically combative. Results of the physical examination disclosed no abnormalities

Journal

JAMA – American Medical Association

Published: Apr 11, 1980

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