Abstract One of the most striking and distressing of the congenital dyskeratotic skin lesions is the rare and peculiar condition of pachyonychia congenita. It is distressing, not only to the patient because of the severe disability involved, but also to the physician because he faces a difficult problem in rehabilitating the persons who are unfortunate enough to have this condition. The scope of this paper includes (1) a review of the various therapeutic modalities in pachyonychia congenita, (2) the presentation of a case, and the use of hypnosis in the treatment. The selection of this method of therapy was stimulated by the report of Mason in which suggestive therapy was of great benefit in a case of congenital ichthyosiform erythroderma of Brocq. Pachyonychia congenita is a type of dyskeratosis with lesions involving chiefly the nails and occasionally the skin and mucous membranes. Transmission is probably by a single References 1. Andrews, G. C.: Pachyonychia Congenita, in Society Transactions , Arch. Dermat. & Syph. 32:501-502, 1935. 2. and Strumwasser, S.: Andrews Pachyonychia Congenita , New York J. Med. 29:747, 1929. 3. Becker, S. W., and Obermayer, M. E.: Modern Dermatology and Syphilology , Ed. 2, Philadelphia, J. B. Lippincott Company, 1947. 4. Diasio, F. A.: Pachyonychia Congenita Jadassohn , Arch. Dermat. & Syph. 30:218, 1934. 5. Felden, B. F.-W.: Pachyonychia Congenita, in Society Transactions , Arch. Dermat. & Syph. 37:1078, 1937. 6. Garb, J.: Pachyonchia Congenita , Arch. Dermat. & Syph. 62:117-124, 1950. 7. Goldberg, L. C.: Resistant Erosive Lesions in Pachyonychia Congenita of jadassohn , Arch. Dermat. & Syph. 36:331-334, 1937. 8. Grace, A. W.: Pachyonychia Congenita, in Society Transactions , Arch. Dermat. & Syph. 36:1255-1256, 1937. 9. Hall-Smith, S. P., and Norton, A.: Psychiatric Survey of a Random Sample of Skin Out-Patients , Brit. M. J. 2:417-421, 1952. 10. Jackson, A. D. M., and Lawler, S. D.: Pachyonychia Congenita: Report of 6 Cases in One Family, with Note on Linkage Data , Ann. Eugenics 16:142-146, 1951. 11. Jadassohn, J., and Lewandowsky, F.: Keratosis Disseminata Circumscripta Tylomata and Keratosis Linguae , Ikonographia Dermatologia 1: 29, 1910. 12. Mason, A. A.: A Case of Congenital Ichthyosiform Erythroderma of Brocq: Treated by Hypnosis , Brit. M. J. 2:422-423, 1952. 13. Porter, A. D., and Haber, H.: Vitamin A in Case of Acquired Localized Keratosis Palmaris et Plantaris and One of Acquired Pachyonychia , Brit. J. Dermat. & Syph. 62:355-358, 1950. 14. Tauber, E. B.; Goldman, L., and Claassen, H.: Pachyonychia Congenita , J. A. M. A. 107:29-30, 1936. 15. Wright, C. S.: Congenital Ectodermal Dysplasia: Pachyonychia Congenita in Society Transactions , Arch. Dermat. & Syph. 47:435, 1943. 16. Wright, C. S., and Guequierre, J. P.: Pachyonychia Congenita , Arch. Dermat. & Syph. 55:819-827, 1947.
A.M.A. Archives of Dermatology – American Medical Association
Published: Feb 1, 1955