Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

P236 Tonsil Carcinoma Treated by Transoral Laser Microsurgery, I: Previously Untreated Tumors

P236 Tonsil Carcinoma Treated by Transoral Laser Microsurgery, I: Previously Untreated Tumors Objective: To report the oncologic and functional outcomes of transoral laser microsurgery (TLM) in the management of previously untreated squamous cell carcinoma of the tonsil. Design: A 2-center prospective case series analysis of TLM in the treatment of tonsillar carcinoma. Setting: Academic tertiary referral centers. Patients: Fifty-four untreated patients were treated with TLM between 1996 and 2005. Pathologic T-stage distribution was T1, 26%; T2, 44%; T3, 20%; and T4, 9%. Thirty-two patients (59%) presented with stage IV disease, 14 (26%) with stage III. Neck dissections were performed in 47 patients (87%). Thirty-two patients (59%) underwent adjuvant radiotherapy. Median follow-up was 30 months; mean, 34 months; range, 1 to 91 months. Interventions: Transoral laser microsurgery with or without neck dissection, adjuvant radiotherapy, or chemotherapy. Main Outcome Measures: Local control, locoregional control, recurrence-free survival, and overall survival. Preoperative and postoperative swallow function was assessed with the Functional Outcome Swallowing Scale. Results: Overall, the 5-year Kaplan-Meier local control estimate was 98%. Five-year overall and recurrence-free survival estimates were 78% and 81%, respectively. For patients with follow-up of 12 months or more (n = 47), 5-year local control, overall survival, and recurrence-free survival estimates were 98%, 77%, and 80%, respectively. Five patients (9%) suffered minor postoperative complications. There was no significant clinical deterioration in swallowing function after TLM. Conclusions: Transoral laser surgery is a safe and effective treatment for select early and advanced carcinoma of the tonsil. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology - Head & Neck Surgery American Medical Association

P236 Tonsil Carcinoma Treated by Transoral Laser Microsurgery, I: Previously Untreated Tumors

P236 Tonsil Carcinoma Treated by Transoral Laser Microsurgery, I: Previously Untreated Tumors

Abstract

Objective: To report the oncologic and functional outcomes of transoral laser microsurgery (TLM) in the management of previously untreated squamous cell carcinoma of the tonsil. Design: A 2-center prospective case series analysis of TLM in the treatment of tonsillar carcinoma. Setting: Academic tertiary referral centers. Patients: Fifty-four untreated patients were treated with TLM between 1996 and 2005. Pathologic T-stage distribution was T1, 26%; T2, 44%; T3, 20%; and T4, 9%. Thirty-two...
Loading next page...
 
/lp/american-medical-association/p236-tonsil-carcinoma-treated-by-transoral-laser-microsurgery-i-0hiZLiUKLn
Publisher
American Medical Association
Copyright
Copyright © 2006 American Medical Association. All Rights Reserved.
ISSN
0886-4470
eISSN
1538-361X
DOI
10.1001/archotol.132.8.911-b
Publisher site
See Article on Publisher Site

Abstract

Objective: To report the oncologic and functional outcomes of transoral laser microsurgery (TLM) in the management of previously untreated squamous cell carcinoma of the tonsil. Design: A 2-center prospective case series analysis of TLM in the treatment of tonsillar carcinoma. Setting: Academic tertiary referral centers. Patients: Fifty-four untreated patients were treated with TLM between 1996 and 2005. Pathologic T-stage distribution was T1, 26%; T2, 44%; T3, 20%; and T4, 9%. Thirty-two patients (59%) presented with stage IV disease, 14 (26%) with stage III. Neck dissections were performed in 47 patients (87%). Thirty-two patients (59%) underwent adjuvant radiotherapy. Median follow-up was 30 months; mean, 34 months; range, 1 to 91 months. Interventions: Transoral laser microsurgery with or without neck dissection, adjuvant radiotherapy, or chemotherapy. Main Outcome Measures: Local control, locoregional control, recurrence-free survival, and overall survival. Preoperative and postoperative swallow function was assessed with the Functional Outcome Swallowing Scale. Results: Overall, the 5-year Kaplan-Meier local control estimate was 98%. Five-year overall and recurrence-free survival estimates were 78% and 81%, respectively. For patients with follow-up of 12 months or more (n = 47), 5-year local control, overall survival, and recurrence-free survival estimates were 98%, 77%, and 80%, respectively. Five patients (9%) suffered minor postoperative complications. There was no significant clinical deterioration in swallowing function after TLM. Conclusions: Transoral laser surgery is a safe and effective treatment for select early and advanced carcinoma of the tonsil.

Journal

Archives of Otolaryngology - Head & Neck SurgeryAmerican Medical Association

Published: Aug 1, 2006

Keywords: neoplasms

There are no references for this article.