Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Otologic Manifestations of Fatal Granulomatosis of Respiratory Tract

Otologic Manifestations of Fatal Granulomatosis of Respiratory Tract The purpose of this paper is to describe the otologic features of fatal granulomatosis of the respiratory tract. Particular emphasis is placed upon the pathologic anatomic findings as seen in serial sections of the paired temporal bones of 2 patients with this disease. Clinical Findings Detailed clinical data concerning the University of Michigan Medical Center patients and selected cases from the literature have been presented previously.1-12 The clinical otologic findings in this report are based upon a study of 18 patients of 124 previously reported, or 14.5% of total cases (Table). Five cases are from the University of Michigan series. The findings are essentially those of chronic middle ear and mastoid suppuration, often the result of salpingitis observed with nasopharyngeal granuloma formation. As is characteristic of Wegener's lethal midline granuloma complex in general, the otitic disease failed to respond to the conventional conservative or surgical therapeutic methods. In one http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngolog American Medical Association

Otologic Manifestations of Fatal Granulomatosis of Respiratory Tract

Archives of Otolaryngolog , Volume 73 (6) – Jun 1, 1961

Loading next page...
 
/lp/american-medical-association/otologic-manifestations-of-fatal-granulomatosis-of-respiratory-tract-wvo27akSlo
Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0003-9977
eISSN
1538-361X
DOI
10.1001/archotol.1961.00740020653003
Publisher site
See Article on Publisher Site

Abstract

The purpose of this paper is to describe the otologic features of fatal granulomatosis of the respiratory tract. Particular emphasis is placed upon the pathologic anatomic findings as seen in serial sections of the paired temporal bones of 2 patients with this disease. Clinical Findings Detailed clinical data concerning the University of Michigan Medical Center patients and selected cases from the literature have been presented previously.1-12 The clinical otologic findings in this report are based upon a study of 18 patients of 124 previously reported, or 14.5% of total cases (Table). Five cases are from the University of Michigan series. The findings are essentially those of chronic middle ear and mastoid suppuration, often the result of salpingitis observed with nasopharyngeal granuloma formation. As is characteristic of Wegener's lethal midline granuloma complex in general, the otitic disease failed to respond to the conventional conservative or surgical therapeutic methods. In one

Journal

Archives of OtolaryngologAmerican Medical Association

Published: Jun 1, 1961

There are no references for this article.