Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Orbital Carcinoid Tumor-Reply

Orbital Carcinoid Tumor-Reply Abstract In Reply. —We very much appreciate the interest of Font et al in our article. When our patient was first seen in 1982, the slides were reviewed in consultation with numerous surgical pathologists, neuropathologists, and ophthalmic pathologists at six medical institutions across the country. There was a consensus that the tumor was neuroendocrine in nature. The diagnoses included esthesioneuroblastoma, metastatic carcinoid tumor, neuroblastoma, and paraganglioma, with the majority favoring a diagnosis of neuroblastoma. At that time, specific keratin antibody stains, as performed by Dr Battifora, were not available.We reviewed Dr Battifora's slides and agree with his interpretation of the tumor's keratin positivity. A polyclonal broad-spectrum antikeratin stain was questionably positive in our laboratory while our anti-AE1/AE3 was strongly positive. The keratin positivity effectively includes a neuroblastoma and is very strong evidence in favor of a carcinoid tumor. In view of these new findings, we completely agree that this is References 1. Zimmerman LE, Stangl R, Riddle PJ. Primary carcinoid tumor of the orbit: a clinicopathologic study with histochemical and electron microscopic observations . Arch Ophthalmol . 1983;101:1395-1398.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Orbital Carcinoid Tumor-Reply

Abstract

Abstract In Reply. —We very much appreciate the interest of Font et al in our article. When our patient was first seen in 1982, the slides were reviewed in consultation with numerous surgical pathologists, neuropathologists, and ophthalmic pathologists at six medical institutions across the country. There was a consensus that the tumor was neuroendocrine in nature. The diagnoses included esthesioneuroblastoma, metastatic carcinoid tumor, neuroblastoma, and paraganglioma, with the...
Loading next page...
 
/lp/american-medical-association/orbital-carcinoid-tumor-reply-FI1MlBp18t
Publisher
American Medical Association
Copyright
Copyright © 1991 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1991.01080030017004
Publisher site
See Article on Publisher Site

Abstract

Abstract In Reply. —We very much appreciate the interest of Font et al in our article. When our patient was first seen in 1982, the slides were reviewed in consultation with numerous surgical pathologists, neuropathologists, and ophthalmic pathologists at six medical institutions across the country. There was a consensus that the tumor was neuroendocrine in nature. The diagnoses included esthesioneuroblastoma, metastatic carcinoid tumor, neuroblastoma, and paraganglioma, with the majority favoring a diagnosis of neuroblastoma. At that time, specific keratin antibody stains, as performed by Dr Battifora, were not available.We reviewed Dr Battifora's slides and agree with his interpretation of the tumor's keratin positivity. A polyclonal broad-spectrum antikeratin stain was questionably positive in our laboratory while our anti-AE1/AE3 was strongly positive. The keratin positivity effectively includes a neuroblastoma and is very strong evidence in favor of a carcinoid tumor. In view of these new findings, we completely agree that this is References 1. Zimmerman LE, Stangl R, Riddle PJ. Primary carcinoid tumor of the orbit: a clinicopathologic study with histochemical and electron microscopic observations . Arch Ophthalmol . 1983;101:1395-1398.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Mar 1, 1991

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month