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Optical Pacemaker

Optical Pacemaker Although light has been used to noninvasively alter the excitability of cardiac tissue in vitro, researchers have now succeeded in using an optical pacemaker to stimulate an intact heart to contract in vivo (Jenkins MW et al. Nat Photonics. 2010;4[9]:623-626). A team led by scientists at Case Western Reserve University in Cleveland, using pulses of infrared laser light at low radiant exposures, were able to reliably pace quail embryo hearts to the laser's pulse frequency without detectable tissue damage. While researchers still face the task of uncovering the mechanisms involved in pacing cardiac cells with laser light and determining if the technology could work with an adult heart, the investigators suggest the technology might one day provide a way to pace the heart without the need for invasive electrodes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Optical Pacemaker

Hampton, Tracy
JAMA , Volume 304 (13) – Oct 6, 2010
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Optical Pacemaker

Abstract

Although light has been used to noninvasively alter the excitability of cardiac tissue in vitro, researchers have now succeeded in using an optical pacemaker to stimulate an intact heart to contract in vivo (Jenkins MW et al. Nat Photonics. 2010;4[9]:623-626). A team led by scientists at Case Western Reserve University in Cleveland, using pulses of infrared laser light at low radiant exposures, were able to reliably pace quail embryo hearts to the laser's pulse frequency without...
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Publisher
American Medical Association
Copyright
Copyright © 2010 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2010.1370
Publisher site
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Abstract

Although light has been used to noninvasively alter the excitability of cardiac tissue in vitro, researchers have now succeeded in using an optical pacemaker to stimulate an intact heart to contract in vivo (Jenkins MW et al. Nat Photonics. 2010;4[9]:623-626). A team led by scientists at Case Western Reserve University in Cleveland, using pulses of infrared laser light at low radiant exposures, were able to reliably pace quail embryo hearts to the laser's pulse frequency without detectable tissue damage. While researchers still face the task of uncovering the mechanisms involved in pacing cardiac cells with laser light and determining if the technology could work with an adult heart, the investigators suggest the technology might one day provide a way to pace the heart without the need for invasive electrodes.

Journal

JAMA – American Medical Association

Published: Oct 6, 2010

Keywords: artificial cardiac pacemaker,optics

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