Abstract • Optic nerve head drusen are rare, inherited concretions, which are almost always calcified; their appearance must be known because they represent one of the major causes of pseudopapilledema. The computed tomographic (CT) scan can show small and buried drusen, which are sometimes difficult to diagnose by the ophthalmoscopic examination. Four cases of drusen (two bilateral and two unilateral) were confirmed or diagnosed by high-resolution CT. The CT appearance of drusen is characteristic because the calcifications are well defined, punctate, and strictly located in the optic disc. The use of high-resolution CT scanners is very helpful. References 1. Daily MJ, Smith JL, Dickens W: Giant drusen (astrocytic hamartoma) of the optic nerve seen with computerized axial tomography . Am J Ophthalmol 1976;81:100-101. 2. Frisen L, Scholdstrom G, Svendsen P: Drusen of the optic nerve head: Verification by computerized tomography . Arch Ophthalmol 1978;96:1611-1614.Crossref 3. Trokel SL, Hilal SK: Submillimeter resolution CT scanning of orbital diseases . Ophthalmology 1980;87:412-417.Crossref 4. Edwards MK, Buncic JR, Harwood-Nash DC: Optic disc drusen . J Comput Assist Tomogr 1982;6:383-384.Crossref 5. Peyster RG, Hoover ED, Hershey BL, et al: High resolution CT of lesions of the optic nerve . AJNR 1983;4:169-174. 6. Turner RM, Gutman I, Hilal SK, et al: CT of drusen bodies and other calcific lesions of the optic nerve: Case report and differential diagnosis . AJNR 1983;4:175-178. 7. Hogan MJ, Zimmerman LE: Ophthalmic Pathology. Philadelphia, WB Saunders Co, 1962. 8. Hoyt WF, Pont ME: Pseudopapilledema: Anomalous elevation of the optic disc: Pitfalls in diagnosis and management . JAMA 1962;181:191-196.Crossref 9. Walsh FB, Hoyt WF: Clinical Neuro-Ophthalmology , ed 3. Baltimore, Williams & Wilkins Co, 1974. 10. Friedman AH, Beckerman B, Gold DH: Drusen of the optic disc . Surv Ophthalmol 1977;21:375-390.Crossref 11. Lorentzen SE: Drusen of the optic disc: A clinical and genetic study . Dan Med Bull 1967; 14:293-298. 12. Reese A: Relation of drusen of the optic nerve to tuberous sclerosis . Arch Ophthalmol 1940;24:187-205.Crossref 13. Friedman AH, Modi S, Gartner S: Drusen of the optic disc: A retrospective study in cadaver eyes . Br J Ophthalmol 1975;59:513-521. 14. Spencer WH: Drusen of the optic disc and aberrant axoplasmic transport . Am J Ophthalmol 1978;85:1-12. 15. Rubinstein K, Muntaz A: Retinal complications of optic disc drusen . Br J Ophthalmol 1982;66:83-95.Crossref 16. Trincao R, Cunha-Vaz JG, Pires JM: Astrocytic hamartoma of the optic disc in localized neuro-fibromatosis (von Recklinghausen's disease) . Ophthalmologica 1973;167:465-469.Crossref 17. Sundheim JL, Lapayowker MS: Calcification and ossification within the orbit . Radiology 1976;121:391-397. 18. Bullock JD, Campbell RJ, Waller RR: Calcification in retinoblastoma . Invest Ophthalmol Vis Sci 1977;16:252-255. 19. Brant-Zawadski M, Enzmann DR: Orbital computed tomography: Calcific densities of the posterior globe . J Comput Assist Tomogr 1979; 3:503-505.Crossref 20. Gass JDM, Guerry RK, Jack RL,et al: Choroidal osteoma . Arch Ophthalmol 1978;96:428-435.Crossref 21. Bisaria KK,Garg KC, Wahal KM: Calcifying orbital hemangioendothelioma . Am J Ophthalmol 1966;62:340-343. 22. Kollarits CR, Moss ML, Cogan DG, et al: Scleral calcifications in hyperparatyroidism: Demonstration by computed tomography . J Comput Assist Tomogr 1977;1:500-504.Crossref 23. Tayebi H: Ocular calcification and retrolental fibroplasia . AJR 1956;76:583-593.
Archives of Ophthalmology – American Medical Association
Published: May 1, 1984