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Oil and Gas on Troubled Waters: The Proliferative Vitreoretinopathy Studies

Oil and Gas on Troubled Waters: The Proliferative Vitreoretinopathy Studies Abstract Clinical trials are expensive and difficult to perform, and yet, when done properly, they are invaluable, for they provide a foundation for informed clinical decisions. Starting with the Diabetic Retinopathy Study, ophthalmologists have benefited from a number of clinical trials that have provided answers to particular treatment-related questions. In this issue of the Archives, there are two reports from the Silicone Oil Study, a multicenter, randomized, clinical trial that was designed to evaluate the benefits and risks of using a long-acting gas bubble or silicone oil as an intraocular tamponade after vitrectomy in eyes with severe proliferative vitreoretinopathy (PVR). Taken together, the reports provide useful information to help guide the selection of an agent for tamponade in the treatment of PVR. See also pp 770 and 780. It should be noted, however, that the value of the information depends on an important assumption, namely, that the only difference between the References 1. Jabs DA, Enger C, Haller J, de Bustros S. Retinal detachment in patients with cytomegalovirus retinitis . Arch Ophthalmol . 1991;109:794-799.Crossref 2. Gardner TW, Norris JL, Zakov ZN, Williams GW. A survey of intraocular gas use in North America . Arch Ophthalmol . 1986;106:1188-1189.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Oil and Gas on Troubled Waters: The Proliferative Vitreoretinopathy Studies

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Publisher
American Medical Association
Copyright
Copyright © 1992 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1992.01080180040026
Publisher site
See Article on Publisher Site

Abstract

Abstract Clinical trials are expensive and difficult to perform, and yet, when done properly, they are invaluable, for they provide a foundation for informed clinical decisions. Starting with the Diabetic Retinopathy Study, ophthalmologists have benefited from a number of clinical trials that have provided answers to particular treatment-related questions. In this issue of the Archives, there are two reports from the Silicone Oil Study, a multicenter, randomized, clinical trial that was designed to evaluate the benefits and risks of using a long-acting gas bubble or silicone oil as an intraocular tamponade after vitrectomy in eyes with severe proliferative vitreoretinopathy (PVR). Taken together, the reports provide useful information to help guide the selection of an agent for tamponade in the treatment of PVR. See also pp 770 and 780. It should be noted, however, that the value of the information depends on an important assumption, namely, that the only difference between the References 1. Jabs DA, Enger C, Haller J, de Bustros S. Retinal detachment in patients with cytomegalovirus retinitis . Arch Ophthalmol . 1991;109:794-799.Crossref 2. Gardner TW, Norris JL, Zakov ZN, Williams GW. A survey of intraocular gas use in North America . Arch Ophthalmol . 1986;106:1188-1189.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jun 1, 1992

References

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