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Ocular Pemphigus: An Electron Microscopic Study of the Conjunctival and Corneal Epithelium

Ocular Pemphigus: An Electron Microscopic Study of the Conjunctival and Corneal Epithelium Abstract Biopsies of the conjunctiva and cornea from a patient with benign mucous membrane pemphigus have been observed electron microscopically. The normally loosely connected conjunctival epithelial cells have become closely interconnected with markedly increased desmosomes, while the normally compact interdigitated corneal epithelium has become widely separated with conspicuously wide intercellular spaces in the basal zone. Goblet cells are absent. Keratin formation is not observed. The epidermalization of this entity may be different from common xerosis. References 1. Wilgram, G.F., et al: Electron Microscopic Studies in Skin Diseases With Acantholysis (Pemphigus vulgaris, Pemphigus familiaris benignus chromicus, Darier's disease) , Derm Wschr 147:281-292 ( (March 23) ) 1964. 2. Wilgram, G.F.; Caulfield, J.B.; and Lever, W.F.: An Electron-Microscopic Study of Acantholysis and Dyskeratosis in Haley's Disease , J Invest Derm 39:373-381 ( (Nov) ) 1962.Crossref 3. Wanko, T.; Lloyd, B.J.; and Matthews, J.: The Fine Structure of Human Conjunctiva in the Perilimbal Zone , Invest Ophthal 3:3 ( (June) ) 1964. 4. Jakus, M.A.: " The Fine Structure of the Human Cornea ," in Smelser, G.K. (ed.): The Structure of the Eye , New York: Academic Press, Inc., 1961. 5. Pedler, C.: The Fine Structure of the Corneal Epithelium , Exp Eye Res 1:286, 1962.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Ocular Pemphigus: An Electron Microscopic Study of the Conjunctival and Corneal Epithelium

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Publisher
American Medical Association
Copyright
Copyright © 1968 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1968.00980050685001
Publisher site
See Article on Publisher Site

Abstract

Abstract Biopsies of the conjunctiva and cornea from a patient with benign mucous membrane pemphigus have been observed electron microscopically. The normally loosely connected conjunctival epithelial cells have become closely interconnected with markedly increased desmosomes, while the normally compact interdigitated corneal epithelium has become widely separated with conspicuously wide intercellular spaces in the basal zone. Goblet cells are absent. Keratin formation is not observed. The epidermalization of this entity may be different from common xerosis. References 1. Wilgram, G.F., et al: Electron Microscopic Studies in Skin Diseases With Acantholysis (Pemphigus vulgaris, Pemphigus familiaris benignus chromicus, Darier's disease) , Derm Wschr 147:281-292 ( (March 23) ) 1964. 2. Wilgram, G.F.; Caulfield, J.B.; and Lever, W.F.: An Electron-Microscopic Study of Acantholysis and Dyskeratosis in Haley's Disease , J Invest Derm 39:373-381 ( (Nov) ) 1962.Crossref 3. Wanko, T.; Lloyd, B.J.; and Matthews, J.: The Fine Structure of Human Conjunctiva in the Perilimbal Zone , Invest Ophthal 3:3 ( (June) ) 1964. 4. Jakus, M.A.: " The Fine Structure of the Human Cornea ," in Smelser, G.K. (ed.): The Structure of the Eye , New York: Academic Press, Inc., 1961. 5. Pedler, C.: The Fine Structure of the Corneal Epithelium , Exp Eye Res 1:286, 1962.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Dec 1, 1968

References