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Novel Influenza A(H1N1) Virus Among Gravid Admissions

Novel Influenza A(H1N1) Virus Among Gravid Admissions ORIGINAL INVESTIGATION Novel Influenza A(H1N1) Virus Among Gravid Admissions Andrew C. Miller, MD; Farnaz Safi, MD; Sadia Hussain, BS; Ramanand A. Subramanian, PhD; Elamin M. Elamin, MD, MSc; Richard Sinert, DO Background: Pandemic novel influenza A(H1N1) is a (n = 3). Demographically, 2 patients were health care substantial threat and cause of morbidity and mortality workers (11%); 15 were black (83%); 2, Hispanic in the pregnant population. (11%); and 1, white (6%). None reported recent travel. Half of the patients presented with gastrointestinal or Methods: We conducted an observational analysis of abdominal complaints; 13 patients met sepsis criteria 18 gravid patients with H1N1 in 2 academic medical cen- (72%). The most common comorbidities were asthma, ters. Cases were identified based on direct antigen test- sickle cell disease, and diabetes. Fourteen patients ing (DAT) of nasopharyngeal swabs followed by real- tested positive for H1N1 on DAT (initial or repeated) time reverse-transcriptase polymerase chain reaction (78%); in the other 4 cases, H1N1 was identified by analysis (rRT-PCR) or viral culture. Patient demograph- viral culture or rRT-PCR (22%). Seven patients deliv- ics, symptoms, hospital course, laboratory and radio- ered during hospitalization (39%), 6 prematurely and 4 graphic results, pregnancy outcome, and placental http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2010.126
pmid
20498414
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION Novel Influenza A(H1N1) Virus Among Gravid Admissions Andrew C. Miller, MD; Farnaz Safi, MD; Sadia Hussain, BS; Ramanand A. Subramanian, PhD; Elamin M. Elamin, MD, MSc; Richard Sinert, DO Background: Pandemic novel influenza A(H1N1) is a (n = 3). Demographically, 2 patients were health care substantial threat and cause of morbidity and mortality workers (11%); 15 were black (83%); 2, Hispanic in the pregnant population. (11%); and 1, white (6%). None reported recent travel. Half of the patients presented with gastrointestinal or Methods: We conducted an observational analysis of abdominal complaints; 13 patients met sepsis criteria 18 gravid patients with H1N1 in 2 academic medical cen- (72%). The most common comorbidities were asthma, ters. Cases were identified based on direct antigen test- sickle cell disease, and diabetes. Fourteen patients ing (DAT) of nasopharyngeal swabs followed by real- tested positive for H1N1 on DAT (initial or repeated) time reverse-transcriptase polymerase chain reaction (78%); in the other 4 cases, H1N1 was identified by analysis (rRT-PCR) or viral culture. Patient demograph- viral culture or rRT-PCR (22%). Seven patients deliv- ics, symptoms, hospital course, laboratory and radio- ered during hospitalization (39%), 6 prematurely and 4 graphic results, pregnancy outcome, and placental

Journal

JAMA Internal MedicineAmerican Medical Association

Published: May 24, 2010

References