Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Nosocomial Scalded Skin Syndrome: Ritter's Disease Caused by Phage Group 3 Staphylococcus aureus

Nosocomial Scalded Skin Syndrome: Ritter's Disease Caused by Phage Group 3 Staphylococcus aureus Abstract • Three cases of generalized exfoliative staphylococcal scalded skin syndrome (SSSS) were encountered during a 25-day period in a nursery for premature infants. A single strain of Staphylococcus aureus, phage type 42E/54/75 (group 3), was recovered from each of the three infants and from no others. Two of the three isolates were tested and both produced epidermolytic toxin (ET). Most cases of SSSS have been associated with phage group 2 strains. To our knowledge, this is the first report of a nursery outbreak caused by a phage group 3 staphylococcus. It illustrates that ET production and not phage type distinguishes S aureus strains that are associated with SSSS. (Am J Dis Child 134:1043-1045, 1980) References 1. Koblenzer PJ: Toxic epidermal necrolysis (TEN; Ritter's disease) and staphylococcal scalded skin syndrome . Clin Pediatr 15:724-730, 1976.Crossref 2. Elias PM, Fritsch P, Epstein EH Jr: Staphylococcal scalded skin syndrome . Arch Dermatol 113:207-219, 1977.Crossref 3. Lyell A: Toxic epidermal necrolysis (the scalded skin syndrome: The expanded clinical syndrome . J Pediatr 68:958-967, 1971. 4. Melish ME, Glasgow LA: Staphylococcal scalded skin syndrome: The expanded clincial syndrome . J Pediatr 68:958-967, 1971.Crossref 5. Sarai Y, Nakahara H, Ishikawa T, et al: A bacteriological study on children with staphylococcal toxic epidermal necrolysis in Japan . Dermatologica 154:161-167, 1977.Crossref 6. Melish ME, Glasgow LA: The staphylococcal scalded skin syndrome . N Engl J Med 282:1114-1119, 1970.Crossref 7. Rycheck RR, Taylor PM, Gezon HM: Epidemic staphylococcal pyoderma associated with Ritter's disease and the appearance of phage type 3B/71 . N Engl J Med 269:332-337, 1963.Crossref 8. Lee HF, Wilson RB, Brown CD, et al: Impetigo and acute infectious exfoliative dermatitis of the newborn infant (Ritter's disease) . J Pediatr 41:159-169, 1952.Crossref 9. Rasmussen JE: Toxic epidermal necrolysis . Arch Dermatol 111:1135-1139, 1975.Crossref 10. Kondo I, Sakurai S, Sarai Y: New type of exfoliatin obtained from staphylococcal strains, belonging to phage groups other than group II, isolated from patients with impetigo and Ritter's disease . Infect Immunity 10:851-861, 1974. 11. Kondo I, Sakurai S, Sarai Y, et al: Two serotypes of exfoliatin and their distribution in staphylococcal strains isolated from patients with scalded skin syndrome . J Clin Microbiol 1:397-400, 1975. 12. Rogolsky M, Warren R, Wiley BB, et al: Nature of the genetic determinant controlling exfoliative toxin production in Staphylococcus aureus . J Bacteriol 117:157-165, 1974. 13. Faden HS, Burke JP, Glasgow LA, et al: Nursery outbreak of scalded skin syndrome: Scarlatiniform rash due to phage group I Staphylococcus aureus . Am J Dis Child 130:265-268, 1976.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Nosocomial Scalded Skin Syndrome: Ritter's Disease Caused by Phage Group 3 Staphylococcus aureus

Loading next page...
 
/lp/american-medical-association/nosocomial-scalded-skin-syndrome-ritter-s-disease-caused-by-phage-KlhaATZNMv
Publisher
American Medical Association
Copyright
Copyright © 1980 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1980.02130230023006
Publisher site
See Article on Publisher Site

Abstract

Abstract • Three cases of generalized exfoliative staphylococcal scalded skin syndrome (SSSS) were encountered during a 25-day period in a nursery for premature infants. A single strain of Staphylococcus aureus, phage type 42E/54/75 (group 3), was recovered from each of the three infants and from no others. Two of the three isolates were tested and both produced epidermolytic toxin (ET). Most cases of SSSS have been associated with phage group 2 strains. To our knowledge, this is the first report of a nursery outbreak caused by a phage group 3 staphylococcus. It illustrates that ET production and not phage type distinguishes S aureus strains that are associated with SSSS. (Am J Dis Child 134:1043-1045, 1980) References 1. Koblenzer PJ: Toxic epidermal necrolysis (TEN; Ritter's disease) and staphylococcal scalded skin syndrome . Clin Pediatr 15:724-730, 1976.Crossref 2. Elias PM, Fritsch P, Epstein EH Jr: Staphylococcal scalded skin syndrome . Arch Dermatol 113:207-219, 1977.Crossref 3. Lyell A: Toxic epidermal necrolysis (the scalded skin syndrome: The expanded clinical syndrome . J Pediatr 68:958-967, 1971. 4. Melish ME, Glasgow LA: Staphylococcal scalded skin syndrome: The expanded clincial syndrome . J Pediatr 68:958-967, 1971.Crossref 5. Sarai Y, Nakahara H, Ishikawa T, et al: A bacteriological study on children with staphylococcal toxic epidermal necrolysis in Japan . Dermatologica 154:161-167, 1977.Crossref 6. Melish ME, Glasgow LA: The staphylococcal scalded skin syndrome . N Engl J Med 282:1114-1119, 1970.Crossref 7. Rycheck RR, Taylor PM, Gezon HM: Epidemic staphylococcal pyoderma associated with Ritter's disease and the appearance of phage type 3B/71 . N Engl J Med 269:332-337, 1963.Crossref 8. Lee HF, Wilson RB, Brown CD, et al: Impetigo and acute infectious exfoliative dermatitis of the newborn infant (Ritter's disease) . J Pediatr 41:159-169, 1952.Crossref 9. Rasmussen JE: Toxic epidermal necrolysis . Arch Dermatol 111:1135-1139, 1975.Crossref 10. Kondo I, Sakurai S, Sarai Y: New type of exfoliatin obtained from staphylococcal strains, belonging to phage groups other than group II, isolated from patients with impetigo and Ritter's disease . Infect Immunity 10:851-861, 1974. 11. Kondo I, Sakurai S, Sarai Y, et al: Two serotypes of exfoliatin and their distribution in staphylococcal strains isolated from patients with scalded skin syndrome . J Clin Microbiol 1:397-400, 1975. 12. Rogolsky M, Warren R, Wiley BB, et al: Nature of the genetic determinant controlling exfoliative toxin production in Staphylococcus aureus . J Bacteriol 117:157-165, 1974. 13. Faden HS, Burke JP, Glasgow LA, et al: Nursery outbreak of scalded skin syndrome: Scarlatiniform rash due to phage group I Staphylococcus aureus . Am J Dis Child 130:265-268, 1976.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Nov 1, 1980

References