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Normal Electroencephalograms in Subacute Sclerosing Panencephalitis

Normal Electroencephalograms in Subacute Sclerosing Panencephalitis Abstract The electroencephalogram is considered to be a reliable aid in the diagnosis of subacute sclerosing panencephalitis (SSPE),1,2 even when the clinical picture is atypical. Since measles antibodies and cerebrospinal fluid (CSF) immunoglobulin determinations are often not readily available, the EEG has assumed a role of great practical importance in the diagnosis of SSPE. These considerations have led us to present a group of patients who initially had normal EEGs, often when SSPE was moderately advanced. Patients and Methods.— Eleven new patients with SSPE were examined (Table). The diagnosis was suspected clinically and confirmed by the finding of an antimeasles titer in the CSF and/or by the demonstration of viral nudeocapsids in glial or neuronal cells in brain tissue.All EEGs were recorded by encephalographs with surface scalp electrodes employing the in ternational 10-20 system of electrode placement and a variety of bipolar and reference montages. In the majority of References 1. Fenyo E, Hasznos T: Periodic EEG complexes in subacute panencephalitis . Electroencephalogr Clin Neurophysiol 16:446-458, 1964.Crossref 2. Cobb W: The periodic events of subacute sclerosing panencephalitis . Electroencephalogr Clin Neurophysiol 21:278-294, 1966.Crossref 3. Jabbour JT, Duenas DA, Sever JL, et al: Epidemiology of subacute sclerosing panencephalitis . JAMA 220:959-962, 1972.Crossref 4. Freeman JM: The clinical spectrum and early diagnosis of Dawson's encephalitis . J Pediatr 75:590-603, 1969.Crossref 5. Ibrahim MM, Jeavons PM: The value of electroencephalography in the diagnosis of SSPE . Dev Med Child Neurol 16:295-307, 1974.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Normal Electroencephalograms in Subacute Sclerosing Panencephalitis

Archives of Neurology , Volume 32 (8) – Aug 1, 1975

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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1975.00490500095015
Publisher site
See Article on Publisher Site

Abstract

Abstract The electroencephalogram is considered to be a reliable aid in the diagnosis of subacute sclerosing panencephalitis (SSPE),1,2 even when the clinical picture is atypical. Since measles antibodies and cerebrospinal fluid (CSF) immunoglobulin determinations are often not readily available, the EEG has assumed a role of great practical importance in the diagnosis of SSPE. These considerations have led us to present a group of patients who initially had normal EEGs, often when SSPE was moderately advanced. Patients and Methods.— Eleven new patients with SSPE were examined (Table). The diagnosis was suspected clinically and confirmed by the finding of an antimeasles titer in the CSF and/or by the demonstration of viral nudeocapsids in glial or neuronal cells in brain tissue.All EEGs were recorded by encephalographs with surface scalp electrodes employing the in ternational 10-20 system of electrode placement and a variety of bipolar and reference montages. In the majority of References 1. Fenyo E, Hasznos T: Periodic EEG complexes in subacute panencephalitis . Electroencephalogr Clin Neurophysiol 16:446-458, 1964.Crossref 2. Cobb W: The periodic events of subacute sclerosing panencephalitis . Electroencephalogr Clin Neurophysiol 21:278-294, 1966.Crossref 3. Jabbour JT, Duenas DA, Sever JL, et al: Epidemiology of subacute sclerosing panencephalitis . JAMA 220:959-962, 1972.Crossref 4. Freeman JM: The clinical spectrum and early diagnosis of Dawson's encephalitis . J Pediatr 75:590-603, 1969.Crossref 5. Ibrahim MM, Jeavons PM: The value of electroencephalography in the diagnosis of SSPE . Dev Med Child Neurol 16:295-307, 1974.Crossref

Journal

Archives of NeurologyAmerican Medical Association

Published: Aug 1, 1975

References