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NONSPECIFIC THERAPY IN DERMATOLOGY: A FIVE YEAR CLINICAL STUDY

NONSPECIFIC THERAPY IN DERMATOLOGY: A FIVE YEAR CLINICAL STUDY Abstract In his exhaustive treatise on "Protein Therapy and Nonspecific Resistance," Petersen stated that the idea of therapy on a nonspecific basis seems a step backward and investigation of such a subject illogical, but that certain therapeutic results cannot be ignored. I am sure that on first acquaintance with nonspecific therapeutic methods the majority of physicians are inclined to view them askance, and it is no wonder that a certain percentage of patients who are subjected to such treatment are inclined to regard it as a new variety of medical hoax. I have known patients on numerous occasions to ask what possible benefit could result from the withdrawal of blood from one part of their body and its reinjection into another part, and later in the course of their treatment to request that the same procedure be carried out. Since 1924, Dr. Schamberg and I have employed various methods of heterotherapy References 1. O'Leary, P. A.: Present Status of Non-specific Therapy , Arch. Dermat. & Syph. 15:470 ( (April) ) 1927. 2. Petersen, W. F.: The Non-Specific Reaction , J. A. M. A. 76:312 ( (Jan. 29) ) 1920. 3. Weichardt, W.: Ueber Proteinkörper Therapie , München. med. Wchnschr. 68:365, 1921. 4. Larson: Principles of Foreign Protein Therapy , Minnesota Med. 2:332, 1919. 5. Starkenstein: Proteinkörper Therapie und Entzündungshemmung , München. med. Wchnschr. 66:205, 1919. 6. Luithlen: Veränderungen der Hautreaktion bei Injection von Serum und kolloidal Substanzen , Wien. klin. Wchnschr. 26:653, 1913. 7. Spiethoff: Zur therapeutischen Verwendung des Eigenserums , München. med. Wchnschr. 60:521, 1913 8. Zur Behandlung mit Eigenserums und Eigenblut , Med. Klin. 9:949, 1913 9. Zur Herabsetzung der Empfindlichkeit der Haut und des Gesamtorganismus durch Injection von Eigenserum, Eigenblut und Natrium Nucleinicum , Dermat. Wchnschr. 42:1227, 1913. 10. Gottheil and Satenstein: Autoserum Injections in Certain Obstinate Dermatoses , M. J. & Rec. 14:620, 1914. 11. Hilario: Autoserotherapy in Diseases of the Skin , J. Cutan. Dis. 32:780, 1914. 12. Fox, Howard: Autogenous Serum in the Treatment of Psoriasis , J. A. M. A. 63:2190 ( (Dec. 19) ) 1914 13. Human Serum and Blood in the Treatment of Psoriasis and Other Skin Diseases , J. Cutan. Dis. 33:616, 1914. 14. Trimble and Rothwell: The Treatment of Psoriasis with Autogenous Serum , J. Cutan. Dis. 33:620, 1915. 15. Willock, J. Scott: Autoserum Therapy in the Treatment of Psoriasis and Other Skin Diseases , J. A. M. A. 65:14 ( (July 3) ) 1915. 16. Schamberg; Gilchrist, and Wile: J. Cutan. Dis. 33:627, 1915. 17. Hebrant; Antoine, and Liegant: Progressive Medicine , Philadelphia, Lea & Febiger, 1925, p. 253. 18. Schulmann, E.: Le traitement autohemotherapique de l'oedeme angioneurotique , Bull. et mém. Soc. méd. d. hôp. de Paris 47:439, 1920 19. L'auto-hemotherapie en dermatologie , Presse méd. 32:254, 1924. 20. Achard and Flandin: Traitement de l'urticaria a repetitions de la maladie de quincke et de rhume des foins par l'autoserotherapie desensibilatrice , Bull. et mém. Soc. méd. d. hôp. de Paris 44:723, 1920. 21. Ullmann and Heuck, quoted by Wein, Salutski and Konigsberg: Die Autohemotherapie bei Eigenen kutanen und venerischen Krankheiten , Dermat. Wchnschr. 79:1629, 1924. 22. Ravaut, quoted by Wein, Salutski, and Konigsberg: Dermat. Wchnschr. 79:1629, 1924. 23. Nicholas, Gate and Du Pasquier: L'autohémotherapie dans les dermatoses , J. de méd. de Lyon 5:291, 1924. 24. Sezary: Traitement des verrues par l'autohémotherapie , Bull. Soc. franç. de dermat. et syph. 35:839, 1928. 25. Schmidt and Saxl, quoted by Petersen: Protein Therapy and Non-specific Resistance , New York, The Macmillan Company, 1922, p. 231. 26. Dziembowski: Ueber den therapeutischen Wert parenteraler Milchzufuhr , Med. Klin. 12:1174, 1916. 27. Reese: Zur Aolanbehandlung der Hautpilzerkrankungen , München. med. Wchnschr. 66:747, 1919. 28. Antoni: Zur Behandlnng der Trichophytien , Dermat. Wchnschr. 67:775, 1918. 29. Kraus: Erfahrungen über Milchtherapie mit besondere Berücksichtigung parasiterer Hauterkrankungen , Dermat. Wchnschr. 67:857, 1918. 30. Weirauk: Non-specific Protein Therapy; Milk in the Treatment of Certain Diseases of the Skin and Syphilis , Ohio State M. J. 22:305, 1926. 31. Greenbaum, Sigmund; and Wright, C. S.: Effects of Non-specific Therapy in Syphilis , Arch. Dermat. & Syph. 10:551 ( (Nov.) ) 1924 32. Non-specific Therapy in Syphilis , Greenbaum Arch. Dermat. & Syph. 12:858 ( (Dec.) ) 1925. 33. Engmann, M. F., and McGarry, R. A.: Treatment of Certain Diseases of the Skin by the Intravenous Injections of Foreign Protein , J. A. M. A. 67: 1741 ( (Dec. 9) ) 1916. 34. Scully, Francis J.: Intravenous Foreign Protein Treatment of Psoriasis , J. A. M. A. 69:1684 ( (Nov. 17) ) 1917. 35. Hazen, H. H.: Therapeutic Results in Psoriasis , South. M. J. 22:932, 1929. 36. Klingmuller: Ueber die Wirkung von Turpentin—Einspritzungen auf Eiterungen und Entzündungen , München. med. Wchnschr. 33:1294, 1918. 37. Levin, O. L., and Rose, E.: Intramuscular Injection of Turpentine in the Treatment of Diseases of the Skin , Arch. Dermat. & Syph. 6:584 ( (Nov.) ) 1922. 38. Czibor: Quoted in abstract in Budapest letter , J. A. M. A. 94:807 ( (March 15) ) 1930. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

NONSPECIFIC THERAPY IN DERMATOLOGY: A FIVE YEAR CLINICAL STUDY

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Publisher
American Medical Association
Copyright
Copyright © 1931 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1931.03880190121010
Publisher site
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Abstract

Abstract In his exhaustive treatise on "Protein Therapy and Nonspecific Resistance," Petersen stated that the idea of therapy on a nonspecific basis seems a step backward and investigation of such a subject illogical, but that certain therapeutic results cannot be ignored. I am sure that on first acquaintance with nonspecific therapeutic methods the majority of physicians are inclined to view them askance, and it is no wonder that a certain percentage of patients who are subjected to such treatment are inclined to regard it as a new variety of medical hoax. I have known patients on numerous occasions to ask what possible benefit could result from the withdrawal of blood from one part of their body and its reinjection into another part, and later in the course of their treatment to request that the same procedure be carried out. Since 1924, Dr. Schamberg and I have employed various methods of heterotherapy References 1. O'Leary, P. A.: Present Status of Non-specific Therapy , Arch. Dermat. & Syph. 15:470 ( (April) ) 1927. 2. Petersen, W. F.: The Non-Specific Reaction , J. A. M. A. 76:312 ( (Jan. 29) ) 1920. 3. Weichardt, W.: Ueber Proteinkörper Therapie , München. med. Wchnschr. 68:365, 1921. 4. Larson: Principles of Foreign Protein Therapy , Minnesota Med. 2:332, 1919. 5. Starkenstein: Proteinkörper Therapie und Entzündungshemmung , München. med. Wchnschr. 66:205, 1919. 6. Luithlen: Veränderungen der Hautreaktion bei Injection von Serum und kolloidal Substanzen , Wien. klin. Wchnschr. 26:653, 1913. 7. Spiethoff: Zur therapeutischen Verwendung des Eigenserums , München. med. Wchnschr. 60:521, 1913 8. Zur Behandlung mit Eigenserums und Eigenblut , Med. Klin. 9:949, 1913 9. Zur Herabsetzung der Empfindlichkeit der Haut und des Gesamtorganismus durch Injection von Eigenserum, Eigenblut und Natrium Nucleinicum , Dermat. Wchnschr. 42:1227, 1913. 10. Gottheil and Satenstein: Autoserum Injections in Certain Obstinate Dermatoses , M. J. & Rec. 14:620, 1914. 11. Hilario: Autoserotherapy in Diseases of the Skin , J. Cutan. Dis. 32:780, 1914. 12. Fox, Howard: Autogenous Serum in the Treatment of Psoriasis , J. A. M. A. 63:2190 ( (Dec. 19) ) 1914 13. Human Serum and Blood in the Treatment of Psoriasis and Other Skin Diseases , J. Cutan. Dis. 33:616, 1914. 14. Trimble and Rothwell: The Treatment of Psoriasis with Autogenous Serum , J. Cutan. Dis. 33:620, 1915. 15. Willock, J. Scott: Autoserum Therapy in the Treatment of Psoriasis and Other Skin Diseases , J. A. M. A. 65:14 ( (July 3) ) 1915. 16. Schamberg; Gilchrist, and Wile: J. Cutan. Dis. 33:627, 1915. 17. Hebrant; Antoine, and Liegant: Progressive Medicine , Philadelphia, Lea & Febiger, 1925, p. 253. 18. Schulmann, E.: Le traitement autohemotherapique de l'oedeme angioneurotique , Bull. et mém. Soc. méd. d. hôp. de Paris 47:439, 1920 19. L'auto-hemotherapie en dermatologie , Presse méd. 32:254, 1924. 20. Achard and Flandin: Traitement de l'urticaria a repetitions de la maladie de quincke et de rhume des foins par l'autoserotherapie desensibilatrice , Bull. et mém. Soc. méd. d. hôp. de Paris 44:723, 1920. 21. Ullmann and Heuck, quoted by Wein, Salutski and Konigsberg: Die Autohemotherapie bei Eigenen kutanen und venerischen Krankheiten , Dermat. Wchnschr. 79:1629, 1924. 22. Ravaut, quoted by Wein, Salutski, and Konigsberg: Dermat. Wchnschr. 79:1629, 1924. 23. Nicholas, Gate and Du Pasquier: L'autohémotherapie dans les dermatoses , J. de méd. de Lyon 5:291, 1924. 24. Sezary: Traitement des verrues par l'autohémotherapie , Bull. Soc. franç. de dermat. et syph. 35:839, 1928. 25. Schmidt and Saxl, quoted by Petersen: Protein Therapy and Non-specific Resistance , New York, The Macmillan Company, 1922, p. 231. 26. Dziembowski: Ueber den therapeutischen Wert parenteraler Milchzufuhr , Med. Klin. 12:1174, 1916. 27. Reese: Zur Aolanbehandlung der Hautpilzerkrankungen , München. med. Wchnschr. 66:747, 1919. 28. Antoni: Zur Behandlnng der Trichophytien , Dermat. Wchnschr. 67:775, 1918. 29. Kraus: Erfahrungen über Milchtherapie mit besondere Berücksichtigung parasiterer Hauterkrankungen , Dermat. Wchnschr. 67:857, 1918. 30. Weirauk: Non-specific Protein Therapy; Milk in the Treatment of Certain Diseases of the Skin and Syphilis , Ohio State M. J. 22:305, 1926. 31. Greenbaum, Sigmund; and Wright, C. S.: Effects of Non-specific Therapy in Syphilis , Arch. Dermat. & Syph. 10:551 ( (Nov.) ) 1924 32. Non-specific Therapy in Syphilis , Greenbaum Arch. Dermat. & Syph. 12:858 ( (Dec.) ) 1925. 33. Engmann, M. F., and McGarry, R. A.: Treatment of Certain Diseases of the Skin by the Intravenous Injections of Foreign Protein , J. A. M. A. 67: 1741 ( (Dec. 9) ) 1916. 34. Scully, Francis J.: Intravenous Foreign Protein Treatment of Psoriasis , J. A. M. A. 69:1684 ( (Nov. 17) ) 1917. 35. Hazen, H. H.: Therapeutic Results in Psoriasis , South. M. J. 22:932, 1929. 36. Klingmuller: Ueber die Wirkung von Turpentin—Einspritzungen auf Eiterungen und Entzündungen , München. med. Wchnschr. 33:1294, 1918. 37. Levin, O. L., and Rose, E.: Intramuscular Injection of Turpentine in the Treatment of Diseases of the Skin , Arch. Dermat. & Syph. 6:584 ( (Nov.) ) 1922. 38. Czibor: Quoted in abstract in Budapest letter , J. A. M. A. 94:807 ( (March 15) ) 1930.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Jan 1, 1931

References

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