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Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population

Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population ORIGINAL CONTRIBUTION Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population Jacob J. Freiberg, MD Context The role of triglycerides in the risk of ischemic stroke remains controversial. Recently, a strong association was found between elevated levels of nonfasting tri- Anne Tybjærg-Hansen, MD, DMSc glycerides, which indicate the presence of remnant lipoproteins, and increased risk of Jan Skov Jensen, MD, DMSc ischemic heart disease. Børge G. Nordestgaard, MD, DMSc Objective To test the hypothesis that increased levels of nonfasting triglycerides are associated with ischemic stroke in the general population. HE ROLE OF TRIGLYCERIDES IN Design, Setting, and Participants The Copenhagen City Heart Study, a prospec- risk of ischemic stroke re- tive, Danish population–based cohort study initiated in 1976, with follow-up through 1-8 mains controversial. Two re- July 2007. Participants were 13 956 men and women aged 20 through 93 years. A Tcent cohort studies reported a cross-sectional study included 9637 individuals attending the 1991-1994 examina- strong association between elevated lev- tion of the prospective study. els of nonfasting, but not fasting, tri- Main Outcome Measures Prospective study: baseline levels of nonfasting triglyc- glycerides and increased risk of myo- erides, other risk factors at baseline and at follow-up http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population

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Publisher
American Medical Association
Copyright
Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2008.621
pmid
19001625
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population Jacob J. Freiberg, MD Context The role of triglycerides in the risk of ischemic stroke remains controversial. Recently, a strong association was found between elevated levels of nonfasting tri- Anne Tybjærg-Hansen, MD, DMSc glycerides, which indicate the presence of remnant lipoproteins, and increased risk of Jan Skov Jensen, MD, DMSc ischemic heart disease. Børge G. Nordestgaard, MD, DMSc Objective To test the hypothesis that increased levels of nonfasting triglycerides are associated with ischemic stroke in the general population. HE ROLE OF TRIGLYCERIDES IN Design, Setting, and Participants The Copenhagen City Heart Study, a prospec- risk of ischemic stroke re- tive, Danish population–based cohort study initiated in 1976, with follow-up through 1-8 mains controversial. Two re- July 2007. Participants were 13 956 men and women aged 20 through 93 years. A Tcent cohort studies reported a cross-sectional study included 9637 individuals attending the 1991-1994 examina- strong association between elevated lev- tion of the prospective study. els of nonfasting, but not fasting, tri- Main Outcome Measures Prospective study: baseline levels of nonfasting triglyc- glycerides and increased risk of myo- erides, other risk factors at baseline and at follow-up

Journal

JAMAAmerican Medical Association

Published: Nov 12, 2008

References

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