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J. Graham, W. McLendon, K. Brinkhous (1953)
MILD HEMOPHILIA: AN ALLELIC FORM OF THE DISEASE°The American Journal of the Medical Sciences, 225
R. Langdell, R. Wagner, K. Brinkhous (1953)
Effect of antihemophilic factor on one-stage clotting tests; a presumptive test for hemophilia and a simple one-stage antihemophilic factor assy procedure.The Journal of laboratory and clinical medicine, 41 4
J. Lewis, J. Ferguson (1953)
Hemorrhagic Diathesis Due to PTC (Plasma Thromboplastin Component) Deficiency.∗Proceedings of the Society for Experimental Biology and Medicine, 82
R. Rosenthal, O. Dreskin, N. Rosenthal (1953)
New Hemophilia-like Disease Caused by Deficiency of a Third Plasma Thromboplastin Factor.∗Proceedings of the Society for Experimental Biology and Medicine, 82
P. Owren (1947)
Parahaemophilia; haemorrhagic diathesis due to absence of a previously unknown clotting factor.Lancet, 1 6449
A. Brink, C. Kingsley (1952)
A familial disorder of blood coagulation due to deficiency of the labile factor.The Quarterly journal of medicine, 21 81
J. Rhoads, T. Fitz-Hugh (1941)
IDIOPATHIC HYPOPROTHROMBINEMIA-AN APPARENTLY UNRECORDED CONDITIONThe American Journal of the Medical Sciences, 202
B. Alexander, R. Goldstein, G. Landwehr, C. Cook, Eunice Addelson, Claire Wilson (1951)
Congenital SPCA deficiency: a hitherto unrecognized coagulation defect with hemorrhage rectified by serum and serum fractions.Journal of Clinical Investigation, 30
Recent studies have shown that hemophilia, even if severe and classical in type, may be easily confused with other hemorrhagic states. Severe hemorrhagic manifestations, including repeated hemarthroses, a family history suggesting a sex-linked recessive inheritance, and laboratory findings, such as a long clotting time, normal prothrombin time, and delayed prothrombin utilization, may all be present; yet the disease may not be true hemophilia. On the other hand, it has been shown that hemophilia may be so mild that the diagnostic procedures in common use are inadequate for diagnosis. In the last fewyears many cases of hemophilia-like disease, different from either the severe or mild forms of hemophilia, have been described. As in hemophilia, there is a bleeding tendency from childhood, and often there are other bleeders in the family. The clotting defects shown by these patients are of several different types. They resemble hemophilia in that there is ineffectual conversion
JAMA – American Medical Association
Published: Feb 6, 1954
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