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Newborn Screening Controversy

Newborn Screening Controversy Opinion VIEWPOINT Past, Present, and Future Newborn screening has been hailed by the US Cen- gan in 1963 when Massachusetts became the first state Michelle Huckaby Lewis, MD, JD ters for Disease Control and Prevention as one of the tomandatescreening.Atthetime,manyresearchersbe- Berman Institute of most successful public health programs of the 21st lieved that it was premature to require mandatory Bioethics, Johns century. The year 2013 marked the 50th anniversary of screening. The American Academy of Pediatrics and the Hopkins University, newborn screening, and the first half century has been American Medical Association initially opposed manda- Baltimore, Maryland. heralded by many triumphs. An estimated 4 million in- tory screening for PKU on the grounds that too little was fants are screened each year under newborn screening known about the reliability of the screening test or the programs that are mandatory in most states, with ap- efficacy of the treatment to justify mandatory proximately 12 500 being identified yearly with certain screening. heritable disorders, many of which have devastating ef- Similar concerns were raised when the advent of fects if not identified and treated prior to the onset of tandem mass spectrometry made possible the detec- symptoms. As new technology has http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Newborn Screening Controversy

Lewis, Michelle Huckaby
JAMA Pediatrics , Volume 168 (3) – Mar 1, 2014
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References (6)

Publisher
American Medical Association
Copyright
Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/jamapediatrics.2013.4980
pmid
24395113
Publisher site
See Article on Publisher Site

Abstract

Opinion VIEWPOINT Past, Present, and Future Newborn screening has been hailed by the US Cen- gan in 1963 when Massachusetts became the first state Michelle Huckaby Lewis, MD, JD ters for Disease Control and Prevention as one of the tomandatescreening.Atthetime,manyresearchersbe- Berman Institute of most successful public health programs of the 21st lieved that it was premature to require mandatory Bioethics, Johns century. The year 2013 marked the 50th anniversary of screening. The American Academy of Pediatrics and the Hopkins University, newborn screening, and the first half century has been American Medical Association initially opposed manda- Baltimore, Maryland. heralded by many triumphs. An estimated 4 million in- tory screening for PKU on the grounds that too little was fants are screened each year under newborn screening known about the reliability of the screening test or the programs that are mandatory in most states, with ap- efficacy of the treatment to justify mandatory proximately 12 500 being identified yearly with certain screening. heritable disorders, many of which have devastating ef- Similar concerns were raised when the advent of fects if not identified and treated prior to the onset of tandem mass spectrometry made possible the detec- symptoms. As new technology has

Journal

JAMA Pediatrics – American Medical Association

Published: Mar 1, 2014

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