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New Insights on How Propranolol May Alleviate PTSD

New Insights on How Propranolol May Alleviate PTSD News & Analysis Lab Reports New Study of Candidate Vaccine to New research in rats reveals that nor- Prevent Chlamydia epinephrine signaling in response to stress Novaccinecurrentlyexiststoprotectagainst can alter the function of the medial pre- infection with the sexually transmitted bac- frontal cortex, leading to impaired fear terium Chlamydia trachomatis, which can extinction and possibly PTSD (Fitzgerald cause female infertility and ectopic pregnan- PJ et al. Proc Natl Acad SciUSA. doi:10.1073 cies and is the leading cause of preventable /pnas.1500682112 [published online June blindness in developing countries. Now, 29, 2015]). Investigators at Texas A&M however, investigators at Harvard Medical University, in College Station, found that School, in Boston, present a promising can- foot-shock stress accompanied by fear didate vaccine consisting of UV light– conditioning changed both the firing rate inactivated C trachomatis tightly conju- and bursting characteristics of neurons in gated to charged nanoparticles carrying an the prelimbic (PL) and infralimbic (IL) adjuvant to boost the immune response regions of the medial prefrontal cortex (Stary G et al. Science. 2015;348[6241]: (mPFC) implicated in fear expression and aaa8205). fear extinction, respectively. A new vaccine strategy uses nanoparticles and a The vaccine protected against C tracho- The team also discovered that http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

New Insights on How Propranolol May Alleviate PTSD

JAMA , Volume 314 (5) – Aug 4, 2015

New Insights on How Propranolol May Alleviate PTSD

Abstract

News & Analysis Lab Reports New Study of Candidate Vaccine to New research in rats reveals that nor- Prevent Chlamydia epinephrine signaling in response to stress Novaccinecurrentlyexiststoprotectagainst can alter the function of the medial pre- infection with the sexually transmitted bac- frontal cortex, leading to impaired fear terium Chlamydia trachomatis, which can extinction and possibly PTSD (Fitzgerald cause female infertility and ectopic pregnan- PJ et al. Proc Natl Acad SciUSA....
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Publisher
American Medical Association
Copyright
Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2015.8966
Publisher site
See Article on Publisher Site

Abstract

News & Analysis Lab Reports New Study of Candidate Vaccine to New research in rats reveals that nor- Prevent Chlamydia epinephrine signaling in response to stress Novaccinecurrentlyexiststoprotectagainst can alter the function of the medial pre- infection with the sexually transmitted bac- frontal cortex, leading to impaired fear terium Chlamydia trachomatis, which can extinction and possibly PTSD (Fitzgerald cause female infertility and ectopic pregnan- PJ et al. Proc Natl Acad SciUSA. doi:10.1073 cies and is the leading cause of preventable /pnas.1500682112 [published online June blindness in developing countries. Now, 29, 2015]). Investigators at Texas A&M however, investigators at Harvard Medical University, in College Station, found that School, in Boston, present a promising can- foot-shock stress accompanied by fear didate vaccine consisting of UV light– conditioning changed both the firing rate inactivated C trachomatis tightly conju- and bursting characteristics of neurons in gated to charged nanoparticles carrying an the prelimbic (PL) and infralimbic (IL) adjuvant to boost the immune response regions of the medial prefrontal cortex (Stary G et al. Science. 2015;348[6241]: (mPFC) implicated in fear expression and aaa8205). fear extinction, respectively. A new vaccine strategy uses nanoparticles and a The vaccine protected against C tracho- The team also discovered that

Journal

JAMAAmerican Medical Association

Published: Aug 4, 2015

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