Abstract Nevus comedonicus is a rare abnormality of the skin characterized by a unilateral and usually linear distribution of groups of comedones. A case is reported in which lesions extend onto the palmar skin. This is the second case reported in which lesions have involved this area. It is the first case to appear in the American literature and the first case in which there has been a microscopic examination of a lesion of the nonhairy skin. The literature, particularly that dealing with variant forms of nevus comedonicus, is reviewed. The pathology of the lesions of the hairy and nonhairy skin is described and the histogenesis of nevus comedonicus is discussed. References 1. Kofmann, S.: Ein fall von seltener Localisation und Verbreitung von Komedonen , Arch Derm Syph 32:177-178 ( (Feb) ) 1895.Crossref 2. Selhorst, S.B.: Naevus Acnéiformis Unilateralis , Brit J Derm 8:419-421 ( (May) ) 1896.Crossref 3. Thibierge, G.: Naevus Acnéique Unilateral en Bandes et en Plaques (Naevus à Comedons) , Ann Derm Syph 7:1298-1303, 1896. 4. White, C.J.: Naevus Follicularis Keratosus , J Cutan Dis 32:187-190 ( (March) ) 1914. 5. Sweitzer, S.E., and Winer, L.H.: Naevus Unilateralis Comedonicus , Arch Derm Syph 26:694-706 ( (Oct) ) 1932.Crossref 6. Beerman, H.B., and Homan, J.B.: Nevus Comedonicus , Arch Klin Exp Derm 208:325-341 ( (March) ) 1959.Crossref 7. Sayer, A.: Naevus Acneiformis Unilateralis (Naevus Follicularis Keratosus) With Report of a Case , Arch Derm Syph 36:1210-1216 ( (Dec) ) 1937.Crossref 8. Anderson, N.P.; Ayres, S.; and Kane, L.M.: Comedone Nevus , Acta Dermatovener 14:299-312, 1933. 9. Paige, T.N., and Mendelson, C.G.: Bilateral Nevus Comedonicus , Arch Derm 96:172-175 ( (Aug) ) 1967.Crossref 10. Rodin, H.H.; Blankenship, M.L.; and Bernstein, G.: Diffuse Familial Comedones , Arch Derm 95:145 ( (Jan) ) 1967. 11. Beatty, J.: Keratosis Punctata at an Unusual Site , Brit J Derm Syph 45:346-349 ( (Aug) -Sept) 1933.Crossref 12. Ebert, M.H.: Ulerythema Acneiforme , Arch Derm Syph 38:292 ( (Aug) ) 1938.Crossref 13. Cohen, E. Lipman: Nevus Comedonicus , Brit J Derm Syph 55:297-298 ( (Dec) ) 1933.Crossref 14. Blaschko, A.: Acne Zosteriformis , Arch Derm Syph 123:242-250 ( (July) ) 1916.Crossref 15. Bernucci, F.: Considerazione su di un nevoacronie lineare a comedoni , Arch Ital Derm 6:26-32 ( (Jan) ) 1930. 16. Senear, F.E., and Perlstein, M.O.: Nevus Unilateralis Comedonicus , Arch Derm Syph 32:680-681 ( (Oct) ) 1935. 17. Piers, F.: Linear Comedo Nevus and Ichthyosis , Brit J Derm Syph 57:138-147 ( (July) -Aug) 1945.Crossref 18. Rupec, M.: Nevus follicularis Keratosus (Naevus Comedonicus) mit Elastoma intrapapillare , Derm Wschr 147:141-148 ( (Feb) ) 1963. 19. Rook, A.J.: Systematized Nevus Comedonicus With Epiletiform Attacks, Case 3 , Proceedings of the Tenth International Congress of Dermatology , London, 1952, p 421-422. 20. Sequeira, J.H.; Ingram, J.T.; and Brain, R.T.: Diseases of the Skin , ed 5, London: J. & A. Churchill, Ltd., 1947. 21. Klein, A: Über einsen halbseitigin systemasierten Naevus follicularis Keratosus , Arch Derm Syph 124:571-583 ( (Sept) ) 1917.Crossref 22. Pinkus, H.: Epithelial and Fibroepithelial Tumors , Arch Derm 91:24-36 ( (Jan) ) 1965.Crossref 23. Montagna, W., and Ellis, R.A.: The Biology of Hair Growth , New York: Academic Press, Inc., 1958. 24. Kryle, J.: Vorlesungen über Histobiologie der menschlichen Haut und ihrer Erkrankungen , Vienna: Julius Springer, 1925, vol 1, p 207.
Archives of Dermatology – American Medical Association
Published: Aug 1, 1968
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