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Ōyanagui Yoshihiko (1976)
Inhibition of superoxide anion production in macrophages by anti-inflammatory drugs.Biochemical Pharmacology, 25
Y. Nishida, K. Tanimoto, I. Akaoka (1981)
Effect of free radicals on lymphocyte response to mitogens and rosette formation.Clinical immunology and immunopathology, 19 3
G. Weissmann, R. Zurier, P. Spieler, I. Goldstein (1971)
MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM LEUKOCYTES EXPOSED TO IMMUNE COMPLEXES AND OTHER PARTICLESThe Journal of Experimental Medicine, 134
Fridovich I (1976)
Free Radicals in Biology
P. Densen, G. Mandell (1978)
Gonococcal interactions with polymorphonuclear neutrophils: importance of the phagosome for bactericidal activity.The Journal of clinical investigation, 62 6
B. Babior (1978)
Oxygen-dependent microbial killing by phagocytes (second of two parts).The New England journal of medicine, 298 13
S. Spielberg, L. Boxer, L. Corash, J. Schulman (1979)
Improved erythrocyte survival with high-dose vitamin E in chronic hemolyzing G6PD and glutathione synthetase deficiencies.Annals of internal medicine, 90 1
K. Ikai, S. Imamura (1976)
Pemphigus-like antibodies in dermatitis herpetiformis.Dermatologica, 152 5
Tanimoto K Nishida H (1981)
Effect of free radicals on the lymphocytesClin Immunol Immunopathol, 19
A. Janoff (1975)
AT LEAST THREE HUMAN NEUTROPHIL LYSOSOMAL PROTEASES ARE CAPABLE OF DEGRADING JOINT CONNECTIVE TISSUES *Annals of the New York Academy of Sciences, 256
Nachman RL Jaffe EA (1973)
Culture of human endothelial cells derived from umbilical veinsJ Clin Invest, 52
A. Macmillan, R. Champion (1973)
Generalized pustular psoriasis treated with DapsoneBritish Journal of Dermatology, 88
Y. Niwa, S. Miyake, T. Sakane, M. Shingu, M. Yokoyama (1982)
Auto-oxidative damage in Behçet's disease--endothelial cell damage following the elevated oxygen radicals generated by stimulated neutrophils.Clinical and experimental immunology, 49 1
G. Weissmann (1972)
Lysosomal mechanisms of tissue injury in arthritis.The New England journal of medicine, 286 3
Y. Niwa, T. Sakane, Y. Miyachi (1984)
Dissociation of the inhibitory effect of dapsone on the generation of oxygen intermediates--in comparison with that of colchicine and various scavengers.Biochemical pharmacology, 33 15
J. McCord, I. Fridovich (1978)
The biology and pathology of oxygen radicals.Annals of internal medicine, 89 1
Maldonado N Necheles TF (1969)
Homozygous erythrocyte glutathione-peroxidase deficiency: Clinical and biochemical studiesBlood, 33
R. Heikkila, F. Cabbat (1978)
CHEMILUMINESCENCE FROM AUTOXIDIZING 6‐HYDROXYDOPAMINE: THE INVOLVEMENT OF ACTIVATED FORMS OF OXYGENPhotochemistry and Photobiology, 28
R. Winkelmann, W. Ditto (1964)
CUTANEOUS AND VISCERAL SYNDROMES OF NECROTIZING OR “ALLERGIC” ANGIITIS: A STUDY OF 38 CASESMedicine, 43
O. Stendahl, L. Molin, C. Dahlgren (1978)
The inhibition of polymorphonuclear leukocyte cytotoxicity by dapsone. A possible mechanism in the treatment of dermatitis herpetiformis.The Journal of clinical investigation, 62 1
S. Katz, W. Strober (1978)
The pathogenesis of dermatitis herpetiformis.The Journal of investigative dermatology, 70 2
J. Skosey, E. Damgaard, D. Chow, L. Sorensen (1974)
MODIFICATION OF ZYMOSAN-INDUCED RELEASE OF LYSOSOMAL ENZYMES FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY CYTOCHALASIN BThe Journal of Cell Biology, 62
S. Klebanoff (1975)
Antimicrobial mechanisms in neutrophilic polymorphonuclear leukocytes.Seminars in hematology, 12 2
I. Fridovich (1976)
CHAPTER 6 – Oxygen Radicals, Hydrogen Peroxide, and Oxygen Toxicity
I. Sneddon, D. Wilkinson (1956)
SUBCORNEAL PUSTULAR DERMATOSIS.British Journal of Dermatology, 68
Y. Ushijima, M. Nakano (1980)
No or little production of singlet molecular oxygen in HOC1 or HOC1/H2O2 a model system for myeloperoxidase/H2O2/C1-.Biochemical and biophysical research communications, 93 4
T. Necheles, N. Maldonado, A. Barquet-Chediak, D. Allen (1969)
Brief Report: Hemozygous Erythrocyte Glutathione-Peroxidase Deficiency: Clinical and Biochemical StudiesBlood, 33
W. Kniker, C. Cochrane (1968)
THE LOCALIZATION OF CIRCULATING IMMUNE COMPLEXES IN EXPERIMENTAL SERUM SICKNESSThe Journal of Experimental Medicine, 127
Jablonska S Chorzelski TP (1979)
Immunopathology of the Skin
Cohen PP (1957)
Monometric Techniques and Tissues Metabolism
K. Takayama, T. Noguchi, M. Nakano (1977)
Reactivities of diphenylfuran (a singlet oxygen trap) with singlet oxygen and hydroxyl radical in aqueous systems.Biochemical and biophysical research communications, 75 4
Chow DC Skosey JL (1981)
Effect of oxygen tension on human peripheral blood leukocytesJ Cell Biol, 88
J. Skosey, D. Chow, E. Damgaard, L. Sorensen (1973)
EFFECT OF CYTOCHALASIN B ON RESPONSE OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES TO ZYMOSANThe Journal of Cell Biology, 57
Babior MB (1978)
Oxygen-dependent microbial killing by phagocytesN Engl J Med, 298
M. Salin, J. McCord (1975)
Free radicals and inflammation. Protection of phagocytosine leukocytes by superoxide dismutase.The Journal of clinical investigation, 56 5
I. Emerit, A. Michelson (1981)
Mechanism of photosensitivity in systemic lupus erythematosus patients.Proceedings of the National Academy of Sciences of the United States of America, 78 4
H. Murray, Z. Cohn (1979)
Macrophage oxygen-dependent antimicrobial activity. I. Susceptibility of Toxoplasma gondii to oxygen intermediatesThe Journal of Experimental Medicine, 150
Y. Miyachi, Y. Niwa (1982)
Effects of potassium iodide, colchicine and dapsone on the generation of polymorphonuclear leukocyte‐derived oxygen intermediatesBritish Journal of Dermatology, 107
D. Miller, H. Kaplan (1970)
Decreased nitroblue tetrazolium dye reduction in the phagocytes of patients receiving prednisone.Pediatrics, 45 5
Erdos G Johnson AR (1977)
Metabolism of vasoactive peptides by human endothelial cells in cultureJ Clin Invest, 59
M. Ward, J. McManus (1975)
Dapsone in crohn's diseaseThe Lancet, 305
T. Maciag, G. Hoover, M. Stemerman, R. Weinstein (1981)
Serial propagation of human endothelial cells in vitroThe Journal of Cell Biology, 91
C. Cochrane (1968)
Immunologic tissue injury mediated by neutrophilic leukocytes.Advances in immunology, 9
E. Jaffe, R. Nachman, C. Becker, C. Minick (1973)
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria.The Journal of clinical investigation, 52 11
J. Skosey, D. Chow, S. Nusinow, J. May, V. Gestautas, Y. Niwa (1981)
Effect of oxygen tension on human peripheral blood leukocytes: lysosomal enzyme release and metabolic responses during phagocytosisThe Journal of Cell Biology, 88
L. Hoyer, Rene Santos, J. Hoyer (1973)
Antihemophilic factor antigen. Localization in endothelial cells by immunofluorescent microscopy.The Journal of clinical investigation, 52 11
K. Williams, R. Capstick, David Lewis, R. Best (1976)
Anti‐inflammatory actions of dapsone and its related biochemistryJournal of Pharmacy and Pharmacology, 28
Molin L Stendahl O (1978)
The inhibition of polymorphonuclear leukocyte cytotoxicity by dapsoneJ Clin Invest, 62
Michelson AM (1982)
Agents and Actions, 11
Michelson AM Emerit I (1981)
Mechanism of photosensitivity in systemic lupus erythematosus patientsProc Natl Acad Sci USA, 78
T. Cornbleet (1951)
SULFOXONE (DIASONE®) SODIUM FOR DERMATITIS HERPETIFORMISArchives of Dermatology, 64
Moldow CF Sacks T (1978)
Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytesJ Clin Invest, 62
Jaffe EA (1976)
Endothelial cells and biology of the factor 8N Engl J Med, 296
Sakane T Niwa Y (1983)
Effect of stimulated neutrophils from the synovial fluid of patients with rheumatoid arthritis on lymphocytes: A possible role of increased oxygen radicals generated by the neutrophilsJ Clin Immunol, 3
Janoff A (1975)
At least three human neutrophil lysosomal proteases are capable of degrading joint connective tissuesAnn NY Acad Sci, 256
E. Jaffe (1977)
Endothelial cells and the biology of factor VIII.The New England journal of medicine, 296 7
H. Murray, C. Juangbhanich, C. Nathan, Z. Cohn (1979)
Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediatesThe Journal of Experimental Medicine, 150
Z. Metzger, J. Hoffeld, J. Oppenheim (1980)
Macrophage-mediated suppression. I. Evidence for participation of both hdyrogen peroxide and prostaglandins in suppression of murine lymphocyte proliferation.Journal of immunology, 124 2
C. Cochrane, E. Unanue, F. Dixon (1965)
A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITISThe Journal of Experimental Medicine, 122
Y. Niwa, K. Sohmiya (1984)
Enhanced neutrophilic functions in mucocutaneous lymph node syndrome, with special reference to the possible role of increased oxygen intermediate generation in the pathogenesis of coronary thromboarteritis.The Journal of pediatrics, 104 1
A. Johnson, E. Erdös (1977)
Metabolism of vasoactive peptides by human endothelial cells in culture. Angiotensin I converting enzyme (kininase II) and angiotensinase.The Journal of clinical investigation, 59 4
C. Cochrane (1971)
MECHANISMS INVOLVED IN THE DEPOSITION OF IMMUNE COMPLEXES IN TISSUESThe Journal of Experimental Medicine, 134
L. Boxer, J. Oliver, S. Spielberg, J.M. Allen, J. Schulman (1979)
Protection of granulocytes by vitamin E in glutathione synthetase deficiency.The New England journal of medicine, 301 17
Hoffeld JT Metzger Z (1980)
Macrophage-mediated suppressionJ Immunol, 124
Cochrane CG Kniker WT (1968)
The localization of immune complexes in experimental serum sickness: The role of vasoactive amines and hydrodynamic forcesJ Exp Med, 127
Abstract • To examine the possible correlation between tissue injury and neutrophil-produced active oxygens (AOs) in patients with linear IgA bullous dermatosis (BD), we studied the capacity of neutrophils from six patients with BD to generate AOs. Cultured endothelial cells from human umbilical-cord vein were also incubated with the patients' neutrophils to assess AO-induced tissue injury. The AO production by patients' neutrophils was significantly elevated. The patients' neutrophils, as well as those from healthy controls preincubated with patients' serum, produced significantly increased levels of cytotoxic response on coincubation with chromium 51-labeled human endothelial cells. These results suggest that the tissue damage observed in BD may be partially due to both excessive production of AOs by neutrophils and a serum factor present in the patients, and further postulate the similar pathogenic process in dermatitis herpetiformis. (Arch Dermatol 1985;121:73-78) References 1. 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Archives of Dermatology – American Medical Association
Published: Jan 1, 1985
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