Abstract • Notable neuropsychologic symptoms persist in a 9-year-old girl one year after an acute exposure to carbon monoxide (CO). Perceptual deficits, personality alterations, and computerized tomographic evidence of leukoencephalopathy persist. Three of five children admitted between 1973 and 1978 with the diagnosis of acute CO intoxication also have residual behavioral and/or school difficulties. Physicians caring for children should consider CO poisoning in the differential diagnosis of an acute encephalopathic state and anticipate its potentially long-term effects. (Am J Dis Child 1981;135:145-147) References 1. Vital Statistics of the US . National Center for Health Statistics, Division of Vital Statistics, 1977, vol 2. 2. Savage EP, Malberg JW, Wheeler HW, et al: Accidental carbon monoxide poisoning in Colorado and Wyoming, 1971-1973 . Public Health Rep 1976;91:560-562. 3. Rose EF, Rose M: Carbon monoxide: A challenge to the physician . Clin Med 1971;78:12-18. 4. Kelley JS, Sophocleus GJ: Retinal hemorrhages in subacute carbon monoxide poisoning: Exposures in homes with blocked furnace flues . JAMA 1978;239:1515-1517.Crossref 5. Veil CL, Bartoli D, Baume S, et al: Bilan psychologique, socioprofessionel, psychopathologique, et physiopathologique a un an de distance de l'intoxication oxycarbone aigue . Ann Med 1970;2:343-398. 6. Smith JS, Brandon S: Morbidity from acute carbon monoxide poisoning at three-year follow-up . Br Med J 1973;1:318-321.Crossref 7. Garland H, Pearce J: Neurological complications of carbon monoxide poisoning . Q J Med 1967;36:445-455. 8. Raskin N, Mullaney OC: The mental and neurological sequelae of carbon monoxide asphyxia in a case observed for 15 years . J Nerv Ment Dis 1940;92:640-659.Crossref 9. Lennox MA, Peterson PB: Electroencephalographic findings in acute CO poisoning . Electroencephalogr Clin Neurophysiol 1958;10:63-68.Crossref 10. Ikeda T, Kondo T, Mogami H, et al: Computerized tomography in cases of acute carbon monoxide poisoning . Med J Osaka Univ 1978; 29:253-262. 11. Ginsberg MD, Myers RE, McDonagh BF: Experimental carbon monoxide encephalopathy in the primate: II. Clinical aspects, neuropathology and physiologic correlation . Arch Neurol 1974;30:209-216.Crossref 12. LaPresle J, Fardeau M: The central nervous system and carbon monoxide poisoning: II. Anatomical study of brain lesions following intoxication with carbon monoxide (22 cases) . Prog Brain Res 1967;24:31-74.
American Journal of Diseases of Children – American Medical Association
Published: Feb 1, 1981
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