Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

NEUROLOGIC MECHANISM FOR CERTAIN PHENOMENA IN TETANY

NEUROLOGIC MECHANISM FOR CERTAIN PHENOMENA IN TETANY Abstract THIS PAPER is first and foremost a contribution to the elucidation of the neurologic mechanism for the Trousseau and von Bonsdorff phenomena, with special regard to the changes in excitability of the nerve during and after ischemia. In the second place, it is intended to throw further light on the mechanism for the spontaneously occurring symptoms of tetany. The Trousseau phenomenon signifies here the tetanic spasm following pneumatic compression of the arm, while the von Bonsdorff phenomenon means the facilitation of tetanic spasm induced by hyperventilation after preceding compression of the arm. Closer analysis shows, however, that not only the spasm but also the sensory symptoms of irritation of the typical spontaneous attack of tetany are obtained when these phenomena are precipitated. The spontaneous attack of tetany is, in fact, reproduced in detail. One may therefore expect to be able to find a single explanation of all three phenomena. It References 1. Grant, S. B., and Goldman, A.: A Study of Forced Respiration: Experimental Production of Tetany , Am. J. Physiol. 52:209, 1920. 2. Mustard, H. J.: A Study of Certain Tonic and Reflex Nervous Impulses as Factors in Parathyroid Tetany , Am. J. Physiol. 29:311, 1912. 3. Carlson, A. J., and Jacobson, C.: Further Studies on the Nature of Parathyroid Tetany , Am. J. Physiol. 28:133, 1911. 4. Paton, D. N.; Findlay, L., and Watson, A: Tetania Parathyreopriva: The Parts of the Central Nervous System Involved , Quart. J. Exper. Physiol. 10:233, 1916. 5. Luckhardt, A. B.; Sherman, M., and Serbin, W. B.: On the Origin of the Muscular Tremors, Clonic and Tonic Spasms in Parathyroid Tetany , Am. J. Physiol. 51:187, 1920. 6. Spiegel, E. A., and Nishikawa, Y.: Der zentrale Mechanismus der Tetaniekrämpfe und ihre Beziehungen zur Enthirnungsstarre , Arb. a. d. neurol. Inst. a. d. Wien. Univ. 24:221, 1923. 7. West, R.: Studies in Neurological Mechanism of Parathyroid Tetany , Brain 58:1, 1935.Crossref 8. Denny-Brown, D., and Pennybacker, J. B.: Fibrillation and Fasciculation in Voluntary Muscle , Brain 61:311, 1938.Crossref 9. Kuffler, S. W.: Excitability Changes at Neuro-Muscular Junction During Tetany , J. Physiol , 103:403, 1945. 10. Kugelberg, E.: (a) Accommodations och rheobasbestämningar i människans motoriska och sensibla nerver , Nord. med. 19:1343, 1943 11. Accommodation in Human Nerves and Its Significance for the Symptoms in Circulatory Disturbances and Tetany , Acta physiol. Scandinav. , 1944, (supp. 24) . 12. Flick, K., and Hansen, K.: Zur Elektrophysiologie sogenannter tonischer Verkürzungszustände quergestreifter Skelettmuskeln: Das Trousseausche Phänomen und die Pfötchenstellung bei der Atmungstetanie , Ztschr. f. Biol. 82:387, 1925. 13. Nothman, M.: Tetanie , in Bumke, O., and Foerster, O.: Handbuch der Neurologie , Berlin, Julius Springer, 1937, vol. 15, p. 173. 14. Lewis, T.: Trousseau's Phenomenon in Tetany , Clin. Sc. 4:361, 1942. 15. Thörner, W.: Ueber das Eregungsstadium der Erstickung und Narkose , Arch. f. d. ges. Physiol. 204:747, 1924.Crossref 16. Heinbecker, P.: Effect of Anoxemia, Carbon Dioxide and Lactic Acid on Electrical Phenomena of Myelinated Fibers of the Peripheral Nervous System , Am. J. Physiol. 89:58, 1929. 17. Lehmann, J. E.: The Effect of Asphyxia on Mammalian A Nerve Fibers , Am. J. Physiol. 119:111, 1937. 18. MacCallum, W. G.: Ueber die Uebererregbarkeit der Nerven bei Tetanie , Mitt. a. d. Grenzgeb. d. Med. u. Chir. 25:941, 1913. 19. Morris, N.: Anoxemia and the Increased Electrical Excitability of the Neuromyone , Brit. J. Exper. Path. 3:101, 1922. 20. Thompson, M., and Kimball, S.: Effect of Local Ischemia upon Human Nerve Fibers in Vivo , Proc. Soc. Exper. Biol. & Med. 34:601, 1936. 21. von Bonsdorff, B.: Några fall av tetani bland värnpliktiga , Finska läk.-sällsk. handl. 72:108, 1930. 22. Lewis, T.; Pickering, G. W., and Rothschild, P.: Centripetal Paralysis Arising Out of Arrested Bloodflow to the Limb, Including Notes on a Form of Tingling , Heart 16:1, 1931. 23. Eccles, J. C., and Sherrington, C. S.: Numbers and Contraction-Values of Individual Motor-Units Examined in Some Muscles of Limb , Proc. Roy. Soc., London, s. B 106:326, 1930.Crossref 24. Björkman, A., and Wohlfart, G.: Faseranalyse de Nn. oculomotorius, trochlearis and abducens des Menschen und des N. abducens verschiedener Tiere , Ztschr.f.mikr.-anat.Forsch. 39:631, 1936. 25. Schwalbe, G.: Ueber die Kaliberverhältnisse der Nervenfasern , Leipzig, F. C. W. Vogel, 1882. 26. Kugelberg, E., and Skoglund, C. R.: To be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology & Psychiatry American Medical Association

NEUROLOGIC MECHANISM FOR CERTAIN PHENOMENA IN TETANY

Archives of Neurology & Psychiatry , Volume 56 (5) – Nov 1, 1946

Loading next page...
 
/lp/american-medical-association/neurologic-mechanism-for-certain-phenomena-in-tetany-Nqny0U0Lga
Publisher
American Medical Association
Copyright
Copyright © 1946 American Medical Association. All Rights Reserved.
ISSN
0096-6754
DOI
10.1001/archneurpsyc.1946.02300220020002
Publisher site
See Article on Publisher Site

Abstract

Abstract THIS PAPER is first and foremost a contribution to the elucidation of the neurologic mechanism for the Trousseau and von Bonsdorff phenomena, with special regard to the changes in excitability of the nerve during and after ischemia. In the second place, it is intended to throw further light on the mechanism for the spontaneously occurring symptoms of tetany. The Trousseau phenomenon signifies here the tetanic spasm following pneumatic compression of the arm, while the von Bonsdorff phenomenon means the facilitation of tetanic spasm induced by hyperventilation after preceding compression of the arm. Closer analysis shows, however, that not only the spasm but also the sensory symptoms of irritation of the typical spontaneous attack of tetany are obtained when these phenomena are precipitated. The spontaneous attack of tetany is, in fact, reproduced in detail. One may therefore expect to be able to find a single explanation of all three phenomena. It References 1. Grant, S. B., and Goldman, A.: A Study of Forced Respiration: Experimental Production of Tetany , Am. J. Physiol. 52:209, 1920. 2. Mustard, H. J.: A Study of Certain Tonic and Reflex Nervous Impulses as Factors in Parathyroid Tetany , Am. J. Physiol. 29:311, 1912. 3. Carlson, A. J., and Jacobson, C.: Further Studies on the Nature of Parathyroid Tetany , Am. J. Physiol. 28:133, 1911. 4. Paton, D. N.; Findlay, L., and Watson, A: Tetania Parathyreopriva: The Parts of the Central Nervous System Involved , Quart. J. Exper. Physiol. 10:233, 1916. 5. Luckhardt, A. B.; Sherman, M., and Serbin, W. B.: On the Origin of the Muscular Tremors, Clonic and Tonic Spasms in Parathyroid Tetany , Am. J. Physiol. 51:187, 1920. 6. Spiegel, E. A., and Nishikawa, Y.: Der zentrale Mechanismus der Tetaniekrämpfe und ihre Beziehungen zur Enthirnungsstarre , Arb. a. d. neurol. Inst. a. d. Wien. Univ. 24:221, 1923. 7. West, R.: Studies in Neurological Mechanism of Parathyroid Tetany , Brain 58:1, 1935.Crossref 8. Denny-Brown, D., and Pennybacker, J. B.: Fibrillation and Fasciculation in Voluntary Muscle , Brain 61:311, 1938.Crossref 9. Kuffler, S. W.: Excitability Changes at Neuro-Muscular Junction During Tetany , J. Physiol , 103:403, 1945. 10. Kugelberg, E.: (a) Accommodations och rheobasbestämningar i människans motoriska och sensibla nerver , Nord. med. 19:1343, 1943 11. Accommodation in Human Nerves and Its Significance for the Symptoms in Circulatory Disturbances and Tetany , Acta physiol. Scandinav. , 1944, (supp. 24) . 12. Flick, K., and Hansen, K.: Zur Elektrophysiologie sogenannter tonischer Verkürzungszustände quergestreifter Skelettmuskeln: Das Trousseausche Phänomen und die Pfötchenstellung bei der Atmungstetanie , Ztschr. f. Biol. 82:387, 1925. 13. Nothman, M.: Tetanie , in Bumke, O., and Foerster, O.: Handbuch der Neurologie , Berlin, Julius Springer, 1937, vol. 15, p. 173. 14. Lewis, T.: Trousseau's Phenomenon in Tetany , Clin. Sc. 4:361, 1942. 15. Thörner, W.: Ueber das Eregungsstadium der Erstickung und Narkose , Arch. f. d. ges. Physiol. 204:747, 1924.Crossref 16. Heinbecker, P.: Effect of Anoxemia, Carbon Dioxide and Lactic Acid on Electrical Phenomena of Myelinated Fibers of the Peripheral Nervous System , Am. J. Physiol. 89:58, 1929. 17. Lehmann, J. E.: The Effect of Asphyxia on Mammalian A Nerve Fibers , Am. J. Physiol. 119:111, 1937. 18. MacCallum, W. G.: Ueber die Uebererregbarkeit der Nerven bei Tetanie , Mitt. a. d. Grenzgeb. d. Med. u. Chir. 25:941, 1913. 19. Morris, N.: Anoxemia and the Increased Electrical Excitability of the Neuromyone , Brit. J. Exper. Path. 3:101, 1922. 20. Thompson, M., and Kimball, S.: Effect of Local Ischemia upon Human Nerve Fibers in Vivo , Proc. Soc. Exper. Biol. & Med. 34:601, 1936. 21. von Bonsdorff, B.: Några fall av tetani bland värnpliktiga , Finska läk.-sällsk. handl. 72:108, 1930. 22. Lewis, T.; Pickering, G. W., and Rothschild, P.: Centripetal Paralysis Arising Out of Arrested Bloodflow to the Limb, Including Notes on a Form of Tingling , Heart 16:1, 1931. 23. Eccles, J. C., and Sherrington, C. S.: Numbers and Contraction-Values of Individual Motor-Units Examined in Some Muscles of Limb , Proc. Roy. Soc., London, s. B 106:326, 1930.Crossref 24. Björkman, A., and Wohlfart, G.: Faseranalyse de Nn. oculomotorius, trochlearis and abducens des Menschen und des N. abducens verschiedener Tiere , Ztschr.f.mikr.-anat.Forsch. 39:631, 1936. 25. Schwalbe, G.: Ueber die Kaliberverhältnisse der Nervenfasern , Leipzig, F. C. W. Vogel, 1882. 26. Kugelberg, E., and Skoglund, C. R.: To be published.

Journal

Archives of Neurology & PsychiatryAmerican Medical Association

Published: Nov 1, 1946

References