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Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome

Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19... Key PointsQuestionWhat is the extent of neurologic involvement in US hospitalized children and adolescents with coronavirus disease 2019 (COVID-19)? FindingsIn this study of 1695 patients 21 years or younger hospitalized for acute COVID-19 or multisystem inflammatory syndrome, 365 (22%) had neurologic involvement. Forty-three patients (12%) developed COVID-19–related life-threatening neurologic disorders, 11 (26%) died, and 17 (40%) survived with new neurologic sequelae. MeaningIn this study, COVID-19–related neurologic involvement was common in hospitalized children and adolescents and mostly transient. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2021.0504
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionWhat is the extent of neurologic involvement in US hospitalized children and adolescents with coronavirus disease 2019 (COVID-19)? FindingsIn this study of 1695 patients 21 years or younger hospitalized for acute COVID-19 or multisystem inflammatory syndrome, 365 (22%) had neurologic involvement. Forty-three patients (12%) developed COVID-19–related life-threatening neurologic disorders, 11 (26%) died, and 17 (40%) survived with new neurologic sequelae. MeaningIn this study, COVID-19–related neurologic involvement was common in hospitalized children and adolescents and mostly transient.

Journal

JAMA NeurologyAmerican Medical Association

Published: May 5, 2021

References