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Neuroleptics

Neuroleptics NEUROLEPTIC medications (eg, phenothiazines, butyrophenones) are used in medicine to control psychotic symptoms and concomitant agitated and violent behavior. They also are used to control anxiety and agitation whenever minor tranquilizers (eg, benzodiazepines) would be inappropriate. Development of akathisia as a parkinsonian side effect is confirmed in the use of these drugs. Akathisia is a condition that gives rise to the subjective desire to be in constant motion, with a feeling of inner agitation and muscle tension. The patient cannot sit still and paces constantly.1 To my knowledge, however, the literature does not contain reports that the development of akathisia can precipitate violence, resulting in the behavior the drug was meant to alleviate. Report of a Case A 29-year-old man had a diagnosis of sociopathic personality and transvestism and a long history of drug abuse, including amphetamines, marijuana, alcohol, LSD, mescaline, benzodiazepines, and narcotics. The patient had a prior http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Neuroleptics

JAMA , Volume 240 (20) – Nov 10, 1978

Neuroleptics

Abstract


NEUROLEPTIC medications (eg, phenothiazines, butyrophenones) are used in medicine to control psychotic symptoms and concomitant agitated and violent behavior. They also are used to control anxiety and agitation whenever minor tranquilizers (eg, benzodiazepines) would be inappropriate. Development of akathisia as a parkinsonian side effect is confirmed in the use of these drugs. Akathisia is a condition that gives rise to the subjective desire to be in constant motion, with a feeling of inner...
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Publisher
American Medical Association
Copyright
Copyright © 1978 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1978.03290200063026
Publisher site
See Article on Publisher Site

Abstract

NEUROLEPTIC medications (eg, phenothiazines, butyrophenones) are used in medicine to control psychotic symptoms and concomitant agitated and violent behavior. They also are used to control anxiety and agitation whenever minor tranquilizers (eg, benzodiazepines) would be inappropriate. Development of akathisia as a parkinsonian side effect is confirmed in the use of these drugs. Akathisia is a condition that gives rise to the subjective desire to be in constant motion, with a feeling of inner agitation and muscle tension. The patient cannot sit still and paces constantly.1 To my knowledge, however, the literature does not contain reports that the development of akathisia can precipitate violence, resulting in the behavior the drug was meant to alleviate. Report of a Case A 29-year-old man had a diagnosis of sociopathic personality and transvestism and a long history of drug abuse, including amphetamines, marijuana, alcohol, LSD, mescaline, benzodiazepines, and narcotics. The patient had a prior

Journal

JAMAAmerican Medical Association

Published: Nov 10, 1978

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