Abstract • Twelve cases of necrotizing enterocolitis (NEC) occurred within three weeks in a neonatal intensive care unit (NICU) with 325 annual admissions. Enterobacter cloacae type 3305573 was found in stool and/or blood cultures from affected babies prior to the onset of the disease. This bacterium could not be grown in cultures from infants in the same NICU six weeks later. A causal relationship between E cloacae and the epidemic of NEC is suggested. (Am J Dis Child 134:1152-1154, 1980) References 1. Virnig NL, Reynolds JW: Epidemiological aspects of neonatal necrotizing enterocolitis . Am J Dis Child 128:186-190, 1974. 2. Speer ME, Taber LH, Yow MD, et al: Fulminant neonatal sepsis and necrotizing associated with a 'nonenteropathogenic' strain of Escherichia coli . J Pediatr 89:91-95, 1976.Crossref 3. Hill HR, Hunt CE, Matsen JM: Nosocomial colonization with Klebsiella type 26 in neonatal ICU associated with an outbreak of sepsis, meningitis, and NEC . J Pediatr 85:415-419, 1974.Crossref 4. Stein H, Beck J, Solomon A, et al: Gastroenteritis with necrotizing enterocolitis in premature babies . Br Med J 2:616-619, 1972.Crossref 5. Howard FM, Flynn DM, Bradley JM, et al: Outbreak of necrotizing enterocolitis caused by Clostridium butyricum . Lancet 2:1099-1102, 1977.Crossref 6. Guinan M, Schaberg D, Bruhn FW, et al: Epidemic occurrence of neonatal necrotizing enterocolitis . Am J Dis Child 133:594-597, 1979. 7. Book LS, Overall JC, Herbst JJ, et al: Clustering of necrotizing enterocolitis: Interruption by infection-control measures . N Engl J Med 297:984-986, 1977.Crossref 8. Bell MJ, Ternberg JL, Feigin RD, et al: Neonatal necrotizing enterocolitis: Therapeutic decision based upon clinical staging . Ann Surg 187:1-7, 1978.Crossref 9. Stoll BJ, Kanto WP, Glass RI, et al: Epidemiology of necrotizing enterocolitis: A case control study . J Pediatr 96:447-451, 1980.Crossref
American Journal of Diseases of Children – American Medical Association
Published: Dec 1, 1980
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