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Necrotic Papules on the Thigh of a 76-Year-Old Woman With Prolonged Fever—Quiz Case

Necrotic Papules on the Thigh of a 76-Year-Old Woman With Prolonged Fever—Quiz Case Report of a case A 76-year-old woman was seen with a 2-month history of fever, malaise, anorexia, and weight loss of 8 kg within 2 months. She also noticed erythematous crusted papules on her left thigh. Her medical history included hypertension, treated with enalapril for 10 years, and cerebral infarction 3 months earlier. She denied any history of recent traveling and had no history of arthralgia, abdominal pain, cough, diarrhea, or abnormal bleeding. She was treated with a 7-day course of oral valacyclovir for her skin lesions without any improvement. Physical examination revealed a few discrete erythematous crusted papules on her left thigh (Figure 1). Skin biopsy specimens were obtained and stained with hematoxylin-eosin (Figure 2) and CD20 immunostain (Figure 3). Figure 1. View LargeDownload Figure 2. View LargeDownload Figure 3. View LargeDownload What is your diagnosis? http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Necrotic Papules on the Thigh of a 76-Year-Old Woman With Prolonged Fever—Quiz Case

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Necrotic Papules on the Thigh of a 76-Year-Old Woman With Prolonged Fever—Quiz Case

Abstract

Report of a case A 76-year-old woman was seen with a 2-month history of fever, malaise, anorexia, and weight loss of 8 kg within 2 months. She also noticed erythematous crusted papules on her left thigh. Her medical history included hypertension, treated with enalapril for 10 years, and cerebral infarction 3 months earlier. She denied any history of recent traveling and had no history of arthralgia, abdominal pain, cough, diarrhea, or abnormal bleeding. She was treated with a 7-day course of...
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Publisher
American Medical Association
Copyright
Copyright © 2011 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archdermatol.2010.403-a
Publisher site
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Abstract

Report of a case A 76-year-old woman was seen with a 2-month history of fever, malaise, anorexia, and weight loss of 8 kg within 2 months. She also noticed erythematous crusted papules on her left thigh. Her medical history included hypertension, treated with enalapril for 10 years, and cerebral infarction 3 months earlier. She denied any history of recent traveling and had no history of arthralgia, abdominal pain, cough, diarrhea, or abnormal bleeding. She was treated with a 7-day course of oral valacyclovir for her skin lesions without any improvement. Physical examination revealed a few discrete erythematous crusted papules on her left thigh (Figure 1). Skin biopsy specimens were obtained and stained with hematoxylin-eosin (Figure 2) and CD20 immunostain (Figure 3). Figure 1. View LargeDownload Figure 2. View LargeDownload Figure 3. View LargeDownload What is your diagnosis?

Journal

Archives of Dermatology – American Medical Association

Published: Jan 1, 2011

Keywords: fever,necrosis,thigh,papule

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