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Necrotic Papules on the Thigh of a 76-Year-Old Woman With Prolonged Fever—Quiz Case

Necrotic Papules on the Thigh of a 76-Year-Old Woman With Prolonged Fever—Quiz Case Report of a case A 76-year-old woman was seen with a 2-month history of fever, malaise, anorexia, and weight loss of 8 kg within 2 months. She also noticed erythematous crusted papules on her left thigh. Her medical history included hypertension, treated with enalapril for 10 years, and cerebral infarction 3 months earlier. She denied any history of recent traveling and had no history of arthralgia, abdominal pain, cough, diarrhea, or abnormal bleeding. She was treated with a 7-day course of oral valacyclovir for her skin lesions without any improvement. Physical examination revealed a few discrete erythematous crusted papules on her left thigh (Figure 1). Skin biopsy specimens were obtained and stained with hematoxylin-eosin (Figure 2) and CD20 immunostain (Figure 3). Figure 1. View LargeDownload Figure 2. View LargeDownload Figure 3. View LargeDownload What is your diagnosis? http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Necrotic Papules on the Thigh of a 76-Year-Old Woman With Prolonged Fever—Quiz Case

Necrotic Papules on the Thigh of a 76-Year-Old Woman With Prolonged Fever—Quiz Case

Abstract

Report of a case A 76-year-old woman was seen with a 2-month history of fever, malaise, anorexia, and weight loss of 8 kg within 2 months. She also noticed erythematous crusted papules on her left thigh. Her medical history included hypertension, treated with enalapril for 10 years, and cerebral infarction 3 months earlier. She denied any history of recent traveling and had no history of arthralgia, abdominal pain, cough, diarrhea, or abnormal bleeding. She was treated with a 7-day course of...
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Publisher
American Medical Association
Copyright
Copyright © 2011 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archdermatol.2010.403-a
Publisher site
See Article on Publisher Site

Abstract

Report of a case A 76-year-old woman was seen with a 2-month history of fever, malaise, anorexia, and weight loss of 8 kg within 2 months. She also noticed erythematous crusted papules on her left thigh. Her medical history included hypertension, treated with enalapril for 10 years, and cerebral infarction 3 months earlier. She denied any history of recent traveling and had no history of arthralgia, abdominal pain, cough, diarrhea, or abnormal bleeding. She was treated with a 7-day course of oral valacyclovir for her skin lesions without any improvement. Physical examination revealed a few discrete erythematous crusted papules on her left thigh (Figure 1). Skin biopsy specimens were obtained and stained with hematoxylin-eosin (Figure 2) and CD20 immunostain (Figure 3). Figure 1. View LargeDownload Figure 2. View LargeDownload Figure 3. View LargeDownload What is your diagnosis?

Journal

Archives of DermatologyAmerican Medical Association

Published: Jan 1, 2011

Keywords: fever,necrosis,thigh,papule

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