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A. Bierman (2001)
Functional statusJournal of General Internal Medicine, 16
Nicole Agaronnik, C. Lindvall, A. El-Jawahri, Wei He, L. Iezzoni (2020)
Use of Natural Language Processing to Assess Frequency of Functional Status Documentation for Patients Newly Diagnosed With Colorectal Cancer.JAMA oncology
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Letters Corresponding Author: Atul Batra, DM, Department of Medical Oncology, PACS 01 trial, the efficacy of 6 cycles of fluorouracil, epirubicin, Dr. BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, and cyclophosphamide (CEF) is inferior to 3 cycles of CEF fol- New Delhi 10029, India (batraatul85@gmail.com). lowed by 3 cycles of docetaxel (CEF-T). Taken together, 6 cycles Published Online: January 7, 2021. doi:10.1001/jamaoncol.2020.7157 of paclitaxel should be inferior to CEF-T. Therefore, we conclude Conflict of Interest Disclosures: None reported. that superiority of PCb to CEF-T is likely due to the addition of 1. Yu K-D, Ye F-G, He M, et al. Effect of adjuvant paclitaxel and carboplatin on carboplatin. In the neoadjuvant setting, findings of the CALGB survival in women with triple-negative breast cancer: a phase 3 randomized clinical 40603 trial have also suggested that the addition of carbopla- trial. JAMA Oncol. 2020;6(9):1390-1396. doi:10.1001/jamaoncol.2020.2965 tin to neoadjuvant paclitaxel followed by dose-dense AC can 2. National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): breast cancer. NCCN Evidence Blocks. Version further improve the pCR rate. 6.2020. Accessed November 30, 2020. https://www.nccn.org/professionals/ Finally, in the current trial, the cardiotoxic events were physician_gls/pdf/breast_blocks.pdf relatively rare, and
JAMA Oncology – American Medical Association
Published: Mar 21, 2021
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