Access the full text.
Sign up today, get DeepDyve free for 14 days.
D. Blumenthal, K. Salzman, K. Digre, R. Jensen, W. Dunson, J. Dalmau (2006)
Early pathologic findings and long-term improvement in anti-Ma2–associated encephalitisNeurology, 67
L. Hoffmann, S. Jarius, H. Pellkofer, M. Schueller, M. Krumbholz, F. Koenig, W. Johannis, C. Fougère, T. Newman, A. Vincent, R. Voltz (2008)
Anti-Ma and anti-Ta associated paraneoplastic neurological syndromes: 22 newly diagnosed patients and review of previous casesJournal of Neurology, Neurosurgery, and Psychiatry, 79
J Jankovic (1985)
Progressive supranuclear palsy: paraneoplastic effect of bronchial carcinoma., 35
S. Overeem, J. Dalmau, L. Bataller, Seiji Nishino, E. Mignot, J. Verschuuren, G. Lammers (2004)
Hypocretin-1 CSF levels in anti-Ma2 associated encephalitisNeurology, 62
J. Dalmau, F. Graus, A. Villarejo, J. Posner, D. Blumenthal, B. Thiessen, A. Saiz, P. Meneses, M. Rosenfeld (2004)
Clinical analysis of anti-Ma2-associated encephalitis.Brain : a journal of neurology, 127 Pt 8
Lumine Matsumoto, Tomotaka Yamamoto, M. Higashihara, I. Sugimoto, H. Kowa, J. Shibahara, Koichiro Nakamura, J. Shimizu, Y. Ugawa, J. Goto, J. Dalmau, S. Tsuji (2007)
Severe hypokinesis caused by paraneoplastic anti‐Ma2 encephalitis associated with bilateral intratubular germ‐cell neoplasm of the testesMovement Disorders, 22
J. Castle, Ai Sakonju, J. Dalmau, D. Newman-Toker (2006)
Anti-Ma2-associated encephalitis with normal FDG-PET: a case of pseudo-Whipple's diseaseNature Clinical Practice Neurology, 2
International Classification of Sleep Disorders: Diagnostic and Coding Manual.
Á. Iranzo, F. Graus, L. Clover, J. Morera, J. Bruna, C. Vilar, J. Martínez-Rodríguez, A. Vincent, J. Santamaria (2006)
Rapid eye movement sleep behavior disorder and potassium channel antibody–associated limbic encephalitisAnnals of Neurology, 59
A. McKeon, M. Apiwattanakul, D. Lachance, V. Lennon, J. Mandrekar, B. Boeve, B. Mullan, B. Mokri, J. Britton, D. Drubach, S. Pittock (2010)
Positron emission tomography-computed tomography in paraneoplastic neurologic disorders: systematic analysis and review.Archives of neurology, 67 3
J. Jankovic (1985)
Progressive supranuclear palsyNeurology, 35
J. Tan, B. Goh, P. Tambyah, E. Wilder-Smith (2005)
Paraneoplastic progressive supranuclear palsy syndrome in a patient with B-cell lymphoma.Parkinsonism & related disorders, 11 3
E. Lein, M. Hawrylycz, Nancy Ao, M. Ayres, Amy Bensinger, Amy Bernard, A. Boe, M. Boguski, Kevin Brockway, Emi Byrnes, Lin Chen, Li Chen, Tsuey-Ming Chen, Mei Chin, Jimmy Chong, Brian Crook, Aneta Czaplinska, Chinh Dang, S. Datta, N. Dee, Aimee Desaki, Tsega Desta, Ellen Diep, Tim Dolbeare, M. Donelan, Hong-wei Dong, J. Dougherty, Ben Duncan, Amanda Ebbert, G. Eichele, Lili Estin, C. Faber, B. Facer, Rick Fields, S. Fischer, Tim Fliss, C. Frensley, Sabrina Gates, Katie Glattfelder, K. Halverson, Matthew Hart, J. Hohmann, Maureen Howell, Darren Jeung, Rebecca Johnson, Patrick Karr, Reena Kawal, Jolene Kidney, Rachel Knapik, C. Kuan, J. Lake, A. Laramee, Kirk Larsen, C. Lau, Tracy Lemon, Agnes Liang, Y. Liu, Lon Luong, Jesse Michaels, J. Morgan, Rebecca Morgan, M. Mortrud, Nerick Mosqueda, Lydia Ng, Randy Ng, Geralyn Orta, C. Overly, Tu Pak, Sheana Parry, S. Pathak, Owen Pearson, R. Puchalski, Z. Riley, Hannah Rockett, S. Rowland, J. Royall, M. Ruiz, N. Sarno, K. Schaffnit, N. Shapovalova, Taz Sivisay, C. Slaughterbeck, Simon Smith, Kimberly Smith, Bryan Smith, Andrew Sodt, Nick Stewart, K. Stumpf, S. Sunkin, Madhavi Sutram, Angelene Tam, C. Teemer, C. Thaller, C. Thompson, Lee Varnam, A. Visel, Ray Whitlock, Paul Wohnoutka, Crissa Wolkey, V. Wong, M. Wood, M. Yaylaoglu, R. Young, Brian Youngstrom, Xuefeng Yuan, Bin Zhang, T. Zwingman, Allan Jones (2007)
Genome-wide atlas of gene expression in the adult mouse brainNature, 445
Y. Compta, Á. Iranzo, J. Santamaria, R. Casamitjana, F. Graus (2007)
REM sleep behavior disorder and narcoleptic features in anti-Ma2-associated encephalitis.Sleep, 30 6
J. Landolfi, M. Nadkarni (2003)
Paraneoplastic limbic encephalitis and possible narcolepsy in a patient with testicular cancer: case study.Neuro-oncology, 5 3
R. Daroff (1991)
The International Classification of Sleep DisordersNeurology, 41
OBSERVATION Narcolepsy, REM Sleep Behavior Disorder, and Supranuclear Gaze Palsy Associated With Ma1 and Ma2 Antibodies and Tonsillar Carcinoma Chris Adams, MS; Andrew McKeon, MD, MRCPI; Michael H. Silber, MB, ChB; Rajeev Kumar, MD Objective: To describe a patient with diencephalic and and symptomatic treatment for parkinsonism and sleep mesencephalic presentation of a Ma1 and Ma2 antibody– disorders. associated paraneoplastic neurological disorder. Main Outcome Measures: Polysomnography, mul- Design: Case report. tiple sleep latency test, and neurological examination. Setting: The Colorado Neurological Institute Move- Results: The cancer was detected at a limited stage and ment Disorders Center in Englewood, Colorado, and the treatable. After oncological therapy and immuno- Mayo Clinic in Rochester, Minnesota. therapy, symptoms stabilized. Treatment with mo- dafinil improved daytime somnolence. Patient: A 55-year-old man with a paraneoplastic neu- rological disorder characterized by rapid eye movement Conclusions: Rapid onset and progression of multifocal sleep behavior disorder, narcolepsy, and a progressive su- deficits may be a clue to paraneoplastic etiology. Early treat- pranuclear palsy–like syndrome in the setting of tonsil- ment of a limited stage cancer (with or without immuno- lar carcinoma. therapy) may possibly slow progression of neurological symptoms. Symptomatic treatment may be beneficial. Intervention: Immunotherapy for paraneoplastic
JAMA Neurology – American Medical Association
Published: Apr 1, 2011
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.