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Myocardial Infarction Risks Remain for Patients Undergoing Noncardiac Elective Surgery

Myocardial Infarction Risks Remain for Patients Undergoing Noncardiac Elective Surgery News & Analysis Myocardial Infarction Risks Remain for Patients Undergoing Noncardiac Elective Surgery Mike Mitka, MSJ ashington, DC—Recent efforts to In the aspirin study, 5628 patients were taking clonidine (47.6%) had clinically im- reduce the not uncommon risk randomly assigned to receive either aspirin portant hypotension compared with 1854 W of myocardial infarction in pa- (200mgjustbeforesurgeryfollowedby100 patients (37.1%) receiving placebo, suggest- tients undergoing noncardiac surgery have mg of aspirin daily for 30 days postsurgery) ing a 32% increased risk with clonidine. Car- turned up empty. or placebo. Another 4998 patients who diac arrest occurred in 16 patients (0.3%) in Researchers presenting findings at the were already taking aspirin were randomly the clonidine group compared with 5 pa- Scientific Sessions of the American College assigned to continue aspirin therapy or to tients (0.1%) in the placebo group (De- of Cardiology (ACC) in March from 2 stud- take a placebo instead. At 30 days, 351 of vereaux PJ et al. N Engl J Med. doi:10.1056 ies using aspirin or clonidine found no re- 4998 patients (7.0%) in the aspirin group /NEJMoa1401106 [published online March duction in the rate of composite death or and 2355 of 5012 patients (7.1%) in the pla- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Myocardial Infarction Risks Remain for Patients Undergoing Noncardiac Elective Surgery

JAMA , Volume 311 (19) – May 21, 2014

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Publisher
American Medical Association
Copyright
Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2014.4461
pmid
24846020
Publisher site
See Article on Publisher Site

Abstract

News & Analysis Myocardial Infarction Risks Remain for Patients Undergoing Noncardiac Elective Surgery Mike Mitka, MSJ ashington, DC—Recent efforts to In the aspirin study, 5628 patients were taking clonidine (47.6%) had clinically im- reduce the not uncommon risk randomly assigned to receive either aspirin portant hypotension compared with 1854 W of myocardial infarction in pa- (200mgjustbeforesurgeryfollowedby100 patients (37.1%) receiving placebo, suggest- tients undergoing noncardiac surgery have mg of aspirin daily for 30 days postsurgery) ing a 32% increased risk with clonidine. Car- turned up empty. or placebo. Another 4998 patients who diac arrest occurred in 16 patients (0.3%) in Researchers presenting findings at the were already taking aspirin were randomly the clonidine group compared with 5 pa- Scientific Sessions of the American College assigned to continue aspirin therapy or to tients (0.1%) in the placebo group (De- of Cardiology (ACC) in March from 2 stud- take a placebo instead. At 30 days, 351 of vereaux PJ et al. N Engl J Med. doi:10.1056 ies using aspirin or clonidine found no re- 4998 patients (7.0%) in the aspirin group /NEJMoa1401106 [published online March duction in the rate of composite death or and 2355 of 5012 patients (7.1%) in the pla-

Journal

JAMAAmerican Medical Association

Published: May 21, 2014

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