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MYCOSIS FUNGOIDE: Diagnosis by Aspiration Technique; Observations in Skin and Bone Marrow

MYCOSIS FUNGOIDE: Diagnosis by Aspiration Technique; Observations in Skin and Bone Marrow Abstract SINCE Stroebel and Hazen in 1911 studied sections of biopsy material of skin in mycosis fungoides and described what they called typical mycosis cells as ``measuring from 8-10 microns in diameter and having an eccentric nucleus," the diagnosis of the disease has depended on the finding of these cells.1 As hematologists, we have been interested primarily in cytology, and our interest has not been confined to the study of blood cells. Starting with the aspiration of bone marrow, we have evolved a simple technique for diagnosis of various diseases, at first, by aspiration from the spleen in many hematological disorders, notably osteosclerotic anemia,2 Gaucher's disease, Hodgkin's disease, and Boeck's sarcoid,3 thence to aspiration of lymph nodes for similar hematological disorders,4 as well as for such malignant conditions as metastatic carcinoma and lymphosarcoma.5 Our search for cytological material was extended to accessible tumors References 1. Stroebel, E. R., and Hazen, H. H.: Mycosis Fungoides in the Negro , J. Cutan. Dis. 29:147, 1911. 2. Morrison, M.; Samwick, A. A.; Rubinstein, J.; Swiller, A. I., and Loewe, L.: Spleen Aspiration in Osteosclerosis and Splenic Hematopoieses: Rationale of Splenectomy , Acta haemat. 6:309, 1951.Crossref 3. Morrison, M.; Samwick, A. A.; Rubinstein, J.; Morrison, H., and Loewe, L.: Splenic Aspiration: Clinical and Hematological Considerations Based on Observations in 105 Cases , J. A. M. A. 146:1575, 1951.Crossref 4. Morrison, M.; Samwick, A. A.; Rubinstein, J.; Stich, M., and Loewe, L.: Lymph Node Aspiration , Am. J. Clin. Path. 22:255, 1952. 5. Morrison, M.; Samwick, A. A.; Rubinstein, J.; Morrison, H.; Stich, M.; Swiller, A. I., and Feldman, S.: Aspiration Technique: Morpho-Cytological Studies, Exhibit at Jewish Sanitarium and Hospital for Chronic Diseases , New York, (Sept.) , 1952. 6. Stich, M.; Eiber, H.; Morrison, M., and Loewe, L.: Cytology of Kaposi Sarcoma , A. M. A. Arch. Dermat. & Syph. 67:85-91, 1953. 7. Ormsby, O. S., and Finnerud, C. W.: Mycosis Fungoides: Report of a Case with Autopsy , Arch. Dermat. & Syph. 27:631, 1933. 8. Ormsby, O. S., and Montgomery, H.: Diseases of the Skin , Ed. 7, Philadelphia, Lea & Febiger, 1948, p. 867. 9. Sutton, R. L., and Sutton, R. L., Jr.: Handbook of Diseases of the Skin , St. Louis, C. V. Mosby Company, 1949, p. 657. 10. Lever, W. F.: Histopathology of Skin , Philadelphia, J. B. Lippincott Company, 1949, p. 424. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

MYCOSIS FUNGOIDE: Diagnosis by Aspiration Technique; Observations in Skin and Bone Marrow

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References (12)

Publisher
American Medical Association
Copyright
Copyright © 1953 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1953.01540040061009
Publisher site
See Article on Publisher Site

Abstract

Abstract SINCE Stroebel and Hazen in 1911 studied sections of biopsy material of skin in mycosis fungoides and described what they called typical mycosis cells as ``measuring from 8-10 microns in diameter and having an eccentric nucleus," the diagnosis of the disease has depended on the finding of these cells.1 As hematologists, we have been interested primarily in cytology, and our interest has not been confined to the study of blood cells. Starting with the aspiration of bone marrow, we have evolved a simple technique for diagnosis of various diseases, at first, by aspiration from the spleen in many hematological disorders, notably osteosclerotic anemia,2 Gaucher's disease, Hodgkin's disease, and Boeck's sarcoid,3 thence to aspiration of lymph nodes for similar hematological disorders,4 as well as for such malignant conditions as metastatic carcinoma and lymphosarcoma.5 Our search for cytological material was extended to accessible tumors References 1. Stroebel, E. R., and Hazen, H. H.: Mycosis Fungoides in the Negro , J. Cutan. Dis. 29:147, 1911. 2. Morrison, M.; Samwick, A. A.; Rubinstein, J.; Swiller, A. I., and Loewe, L.: Spleen Aspiration in Osteosclerosis and Splenic Hematopoieses: Rationale of Splenectomy , Acta haemat. 6:309, 1951.Crossref 3. Morrison, M.; Samwick, A. A.; Rubinstein, J.; Morrison, H., and Loewe, L.: Splenic Aspiration: Clinical and Hematological Considerations Based on Observations in 105 Cases , J. A. M. A. 146:1575, 1951.Crossref 4. Morrison, M.; Samwick, A. A.; Rubinstein, J.; Stich, M., and Loewe, L.: Lymph Node Aspiration , Am. J. Clin. Path. 22:255, 1952. 5. Morrison, M.; Samwick, A. A.; Rubinstein, J.; Morrison, H.; Stich, M.; Swiller, A. I., and Feldman, S.: Aspiration Technique: Morpho-Cytological Studies, Exhibit at Jewish Sanitarium and Hospital for Chronic Diseases , New York, (Sept.) , 1952. 6. Stich, M.; Eiber, H.; Morrison, M., and Loewe, L.: Cytology of Kaposi Sarcoma , A. M. A. Arch. Dermat. & Syph. 67:85-91, 1953. 7. Ormsby, O. S., and Finnerud, C. W.: Mycosis Fungoides: Report of a Case with Autopsy , Arch. Dermat. & Syph. 27:631, 1933. 8. Ormsby, O. S., and Montgomery, H.: Diseases of the Skin , Ed. 7, Philadelphia, Lea & Febiger, 1948, p. 867. 9. Sutton, R. L., and Sutton, R. L., Jr.: Handbook of Diseases of the Skin , St. Louis, C. V. Mosby Company, 1949, p. 657. 10. Lever, W. F.: Histopathology of Skin , Philadelphia, J. B. Lippincott Company, 1949, p. 424.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Apr 1, 1953

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