Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Mycobacteriosis in Patients With Malignant Disease

Mycobacteriosis in Patients With Malignant Disease Abstract Mycobacteriosis was found in 59 patients with malignant disease in a five-year period from 1968 to 1973. Thirty patients (51%) had mycobacteriosis that was caused by atypical mycobacteria. The most frequent organisms were Mycobacterium kansasii and M fortuitum. The most frequent tumors associated with mycobacteriosis were squamous cell carcinoma of the head and neck, testicular carcinoma, and lung carcinoma. The only predisposing factor was treatment with cancer chemotherapy. Mortality due to mycobacterial infections was most frequently associated with those infections caused by M tuberculosis. Although mycobacteriosis is relatively uncommon in cancer patients, if it is present, atypical mycobacteria should be looked for because, in these patients, these organisms cause more than 50% of mycobacteriosis. (Arch Intern Med 136:67-70,Z 1976) References 1. Parker F Jr, Jackson H Jr, Bethae JM, et al: Studies of diseases of the lymphoid and myeloid tissues: Coexistence of tuberculosis with Hodgkin's disease and other forms of malignant lymphoma . Am J Med Sci 184:694-699, 1932.Crossref 2. Lowther CP: Leukemia and tuberculosis . Ann Intern Med 51:52-56, 1959.Crossref 3. Morrow LB, Anderson RE: Active tuberculosis in leukemia . Arch Pathol 79:484-493, 1965. 4. Snider GL: Bronchogenic carcinoma and pulmonary tuberculosis . Dis Chest 55:181-182, 1969.Crossref 5. Rosenblatt MB: Association of bronchogenic carcinoma and pulmonary tuberculosis . Geri atrics 29:99-108, 1965. 6. Stead WW: Mycobacterial diseases , in Wintrobe MM, Thorn GW, Adams RD, et al (eds): Harrison's Principles of Internal Medicine , ed 7. New York, McGraw-Hill Book Co Inc, 1974, pp 858-870. 7. McNutt DR, Fundenberg HH: Disseminated scotochromogen infection and unusual myeloproliferative disorder . Ann Intern Med 75:737-744, 1971.Crossref 8. Engstrom PF, Dewey GC, Barrett O Jr: Disseminated Mycobacterium kansasii infection . Am J Med 52:533-537, 1972.Crossref 9. Runyon EH: Anonymous mycobacteria in pulmonary disease . Med Clin North Am 42:273-290, 1959. 10. Fischer DA, Lester W, Schaefer WB: Infections with atypical mycobacteria . Am Rev Respir Dis 98:29-34, 1968. 11. Hand WL, Sanford JP: Mycobacterium fortuitum: A human pathogen . Ann Intern Med 73:971-977, 1970.Crossref 12. Beck F: Pulmonary disease due to atypical tubercule bacilli . Am Rev Respir Dis 80:738-743, 1959. 13. Corpe RF, Smith CE, Stergus I: Death due to Mycobacterium fortuitum . JAMA 177:262-263, 1961.Crossref 14. Chapman JS: Atypical mycobacterial infections . Med Clin North Am 51:503-517, 1967. 15. Wolinsky E: Mycobacteria , in Davis BD, Dulbeceo R, Eisen HN, et al (eds): Microbiology . San Francisco, Harper & Row, 1973, pp 844-869. 16. Kaplan MH, Armstrong D, Rosen P: Tuberculosis complicating neoplastic disease . Can cer 33:850-858, 1974.Crossref 17. Bonlek LI: Diagnosis of lung cancer in tuberculosis patients . Chest 60:256-259, 1971.Crossref 18. Bodey GP, Buckley M, Sathe YS, et al: Quantitative relationships between circulating leukocytes and infections in patients with acute leukemia . Ann Intern Med 64:328-340, 1966.Crossref 19. Palmer CE, Edwards LB: Identifying the tuberculosis infected: The dual test technique . JAMA 205:167-169, 1968.Crossref 20. Fugan L: PPD antigens and the diagnosis of mycobacterial disease . Arch Intern Med 124:49-54, 1969..Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Mycobacteriosis in Patients With Malignant Disease

Loading next page...
 
/lp/american-medical-association/mycobacteriosis-in-patients-with-malignant-disease-Uey6eG5sI0
Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1976.03630010051009
Publisher site
See Article on Publisher Site

Abstract

Abstract Mycobacteriosis was found in 59 patients with malignant disease in a five-year period from 1968 to 1973. Thirty patients (51%) had mycobacteriosis that was caused by atypical mycobacteria. The most frequent organisms were Mycobacterium kansasii and M fortuitum. The most frequent tumors associated with mycobacteriosis were squamous cell carcinoma of the head and neck, testicular carcinoma, and lung carcinoma. The only predisposing factor was treatment with cancer chemotherapy. Mortality due to mycobacterial infections was most frequently associated with those infections caused by M tuberculosis. Although mycobacteriosis is relatively uncommon in cancer patients, if it is present, atypical mycobacteria should be looked for because, in these patients, these organisms cause more than 50% of mycobacteriosis. (Arch Intern Med 136:67-70,Z 1976) References 1. Parker F Jr, Jackson H Jr, Bethae JM, et al: Studies of diseases of the lymphoid and myeloid tissues: Coexistence of tuberculosis with Hodgkin's disease and other forms of malignant lymphoma . Am J Med Sci 184:694-699, 1932.Crossref 2. Lowther CP: Leukemia and tuberculosis . Ann Intern Med 51:52-56, 1959.Crossref 3. Morrow LB, Anderson RE: Active tuberculosis in leukemia . Arch Pathol 79:484-493, 1965. 4. Snider GL: Bronchogenic carcinoma and pulmonary tuberculosis . Dis Chest 55:181-182, 1969.Crossref 5. Rosenblatt MB: Association of bronchogenic carcinoma and pulmonary tuberculosis . Geri atrics 29:99-108, 1965. 6. Stead WW: Mycobacterial diseases , in Wintrobe MM, Thorn GW, Adams RD, et al (eds): Harrison's Principles of Internal Medicine , ed 7. New York, McGraw-Hill Book Co Inc, 1974, pp 858-870. 7. McNutt DR, Fundenberg HH: Disseminated scotochromogen infection and unusual myeloproliferative disorder . Ann Intern Med 75:737-744, 1971.Crossref 8. Engstrom PF, Dewey GC, Barrett O Jr: Disseminated Mycobacterium kansasii infection . Am J Med 52:533-537, 1972.Crossref 9. Runyon EH: Anonymous mycobacteria in pulmonary disease . Med Clin North Am 42:273-290, 1959. 10. Fischer DA, Lester W, Schaefer WB: Infections with atypical mycobacteria . Am Rev Respir Dis 98:29-34, 1968. 11. Hand WL, Sanford JP: Mycobacterium fortuitum: A human pathogen . Ann Intern Med 73:971-977, 1970.Crossref 12. Beck F: Pulmonary disease due to atypical tubercule bacilli . Am Rev Respir Dis 80:738-743, 1959. 13. Corpe RF, Smith CE, Stergus I: Death due to Mycobacterium fortuitum . JAMA 177:262-263, 1961.Crossref 14. Chapman JS: Atypical mycobacterial infections . Med Clin North Am 51:503-517, 1967. 15. Wolinsky E: Mycobacteria , in Davis BD, Dulbeceo R, Eisen HN, et al (eds): Microbiology . San Francisco, Harper & Row, 1973, pp 844-869. 16. Kaplan MH, Armstrong D, Rosen P: Tuberculosis complicating neoplastic disease . Can cer 33:850-858, 1974.Crossref 17. Bonlek LI: Diagnosis of lung cancer in tuberculosis patients . Chest 60:256-259, 1971.Crossref 18. Bodey GP, Buckley M, Sathe YS, et al: Quantitative relationships between circulating leukocytes and infections in patients with acute leukemia . Ann Intern Med 64:328-340, 1966.Crossref 19. Palmer CE, Edwards LB: Identifying the tuberculosis infected: The dual test technique . JAMA 205:167-169, 1968.Crossref 20. Fugan L: PPD antigens and the diagnosis of mycobacterial disease . Arch Intern Med 124:49-54, 1969..Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jan 1, 1976

References