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Mycobacterial Ocular Inflammation

Mycobacterial Ocular Inflammation CLINICAL SCIENCES Delay in Diagnosis and Other Factors Impacting Morbidity Sarju S. Patel, MD, MPH, MSc; Nehali V. Saraiya, MD; Howard H. Tessler, MD; Debra A. Goldstein, MD Importance: The reported outcomes of ocular myco- cobacterial infection. Chest imaging was consistent with bacterial infection are commonly unfavorable. This study granulomatous disease in 46.7%. Average delay from ocu- is among the first to elucidate factors associated with poor lar disease onset to uveitis service referral was 755.3 days. outcomes, as well as highlight the continued controver- Posterior uveitis and non-Hispanic white race were as- sies in therapy, particularly the role of oral corticoste- sociated with increased delay. A relapsing course was ob- roids. served in posterior uveitis (odds ratio [OR], 20.0; 95% CI, 1.39-287; P=.03) and those treated with systemic ste- Objective: To describe presentations and outcomes of roids for eye disease (OR, 10.1; 95% CI,1.60-64.0; P=.01). mycobacterial ocular disease in the Midwestern United Disease control was achieved in 81%, although 38.5% had States. profound visual loss, associated with age older than 50 years and delay in diagnosis. Patients diagnosed after 500 Design: Retrospective case series. days from initial ocular symptoms were more likely to lose vision (OR, 20.0; 95% http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/jamaophthalmol.2013.71
pmid
23579549
Publisher site
See Article on Publisher Site

Abstract

CLINICAL SCIENCES Delay in Diagnosis and Other Factors Impacting Morbidity Sarju S. Patel, MD, MPH, MSc; Nehali V. Saraiya, MD; Howard H. Tessler, MD; Debra A. Goldstein, MD Importance: The reported outcomes of ocular myco- cobacterial infection. Chest imaging was consistent with bacterial infection are commonly unfavorable. This study granulomatous disease in 46.7%. Average delay from ocu- is among the first to elucidate factors associated with poor lar disease onset to uveitis service referral was 755.3 days. outcomes, as well as highlight the continued controver- Posterior uveitis and non-Hispanic white race were as- sies in therapy, particularly the role of oral corticoste- sociated with increased delay. A relapsing course was ob- roids. served in posterior uveitis (odds ratio [OR], 20.0; 95% CI, 1.39-287; P=.03) and those treated with systemic ste- Objective: To describe presentations and outcomes of roids for eye disease (OR, 10.1; 95% CI,1.60-64.0; P=.01). mycobacterial ocular disease in the Midwestern United Disease control was achieved in 81%, although 38.5% had States. profound visual loss, associated with age older than 50 years and delay in diagnosis. Patients diagnosed after 500 Design: Retrospective case series. days from initial ocular symptoms were more likely to lose vision (OR, 20.0; 95%

Journal

JAMA OphthalmologyAmerican Medical Association

Published: Jun 1, 2013

References

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