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Multiple Granular Cell Tumors: A Familial Occurrence in Children

Multiple Granular Cell Tumors: A Familial Occurrence in Children Abstract • A 23-year-old black woman and her 6-year-old son, both with multiple granular cell tumors, are described herein. The mother and son both presented as children with multiple granular cell tumors. This is the first reported case of multiple lesions arising in childhood in successive generations. Only two other case studies of familial granular cell tumors have been reported, but in neither of these cases did multiple tumors present initially in both family members during childhood. A preponderance of multicentric lesions is reported in blacks. The tumors recurred locally in some of the sites where there were inadequate surgical margins, emphasizing the need for complete excision. (Arch Surg 1986;121:945-947) References 1. Abrikossoff AI: Weitere Untersuchungen uber Myoblastenmyome . Virchow Arch Pathol Anat 1931;280:723-740.Crossref 2. Murray DE, Seaman E, Utzinger WU: Granular cell myoblastomas in successive generations . J Surg Oncol 1969;2:193-197.Crossref 3. Baraf CS, Bender B: Multiple cutaneous granular cell myoblastoma . Arch Dermatol 1964;89:243-246.Crossref 4. White SW, Gallager RL, Rodman OG: Multiple granular cell tumors . J Dermatol Surg Oncol 1980;6:157-161. 5. Frable M, Fischer RA: Granular cell myoblastomas . Laryngoscope 1975;6:36-41. 6. McSwain GR, Colpitis R, Kreutner A, et al: Granular cell myoblastoma . Surg Gynecol Obstet 1980;150:703-710. 7. Lack EE, Worsham F, Callihan MD, et al: Granular cell tumor: A clinicopathologic study of 110 patients . J Surg Oncol 1980;13:301-316.Crossref 8. Pressor R, Chung EB: Granular cell tumor in black patients . Natl Med Assoc 1980;72:1171-1175. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Multiple Granular Cell Tumors: A Familial Occurrence in Children

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Publisher
American Medical Association
Copyright
Copyright © 1986 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1986.01400080091017
Publisher site
See Article on Publisher Site

Abstract

Abstract • A 23-year-old black woman and her 6-year-old son, both with multiple granular cell tumors, are described herein. The mother and son both presented as children with multiple granular cell tumors. This is the first reported case of multiple lesions arising in childhood in successive generations. Only two other case studies of familial granular cell tumors have been reported, but in neither of these cases did multiple tumors present initially in both family members during childhood. A preponderance of multicentric lesions is reported in blacks. The tumors recurred locally in some of the sites where there were inadequate surgical margins, emphasizing the need for complete excision. (Arch Surg 1986;121:945-947) References 1. Abrikossoff AI: Weitere Untersuchungen uber Myoblastenmyome . Virchow Arch Pathol Anat 1931;280:723-740.Crossref 2. Murray DE, Seaman E, Utzinger WU: Granular cell myoblastomas in successive generations . J Surg Oncol 1969;2:193-197.Crossref 3. Baraf CS, Bender B: Multiple cutaneous granular cell myoblastoma . Arch Dermatol 1964;89:243-246.Crossref 4. White SW, Gallager RL, Rodman OG: Multiple granular cell tumors . J Dermatol Surg Oncol 1980;6:157-161. 5. Frable M, Fischer RA: Granular cell myoblastomas . Laryngoscope 1975;6:36-41. 6. McSwain GR, Colpitis R, Kreutner A, et al: Granular cell myoblastoma . Surg Gynecol Obstet 1980;150:703-710. 7. Lack EE, Worsham F, Callihan MD, et al: Granular cell tumor: A clinicopathologic study of 110 patients . J Surg Oncol 1980;13:301-316.Crossref 8. Pressor R, Chung EB: Granular cell tumor in black patients . Natl Med Assoc 1980;72:1171-1175.

Journal

Archives of SurgeryAmerican Medical Association

Published: Aug 1, 1986

References