Abstract To the Editor. —Multiple exostoses syndrome is a disorder consisting of multiple projections of endochondral bone capped by cartilage. Generally, they appear and are most numerous in the metaphysis of long bones, although their existence is also possible in flat bones and vertebrae. This condition is inherited by autosomal dominant transmission. We describe a child with an unusual presentation of multiple exostoses syndrome: nail plate deformity of the fingers due to several small exostoses of phalanges. Report of a Case. —A 14-year-old boy presented with nail plate deformity consisting of nail malalignment, longitudinal dystrophy, and swelling of the nail fold on several fingers that had developed slowly since birth. A roentgenogram showed multiple exostoses on the distal phalanges and also in the long bones. The child's general condition was good, and laboratory studies showed normal findings. His father and other relatives suffered from the same skeletal abnormalities (multiple palpable nodular References 1. Solomon L. Hereditary multiple exostosis . J Bone Joint Surg Br . 1963; 45:292-304. 2. Crandall BF, Field LL, Sparkes RS. Spence MA. Hereditary multiple exostoses: report of a family . Clin Orthop . 1984;190:217-219. 3. Solomon L. Chondrosarcoma in hereditary multiple exostosis . S Afr Med J . 1974;48:671-676. 4. Hazen PG. Smith DE. Hereditary multiple exostoses: report of a case presenting with proximal nail fold and nail swelling . J Am Acad Dermatol . 1990;22:132-134.Crossref 5. Baran R, Bureau H. Multiple exostoses syndrome . J Am Acad Dermatol . 1991;25:333-335.Crossref
Archives of Dermatology – American Medical Association
Published: Dec 1, 1992
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