Abstract REPORT OF A CASE A 66-year-old white male chemical engineer with a history of type II diabetes, parkinsonism, ankylosing spondylitis, esophageal diverticuli, and major depression presented for evaluation of a pruritic ''rash'' on his back. This rash has been present since the early 1960s. He had received two cycles of radiotherapy to his lower back to treat his ankylosing spondylitis. The first cycle began in 1954 and consisted of radiotherapy two to three times per week for 3 months. The amount and type of radiation the patient received is unknown. The second cycle was performed several years later. Initially, the lesions were reported to disappear with sunlight exposure. In the early 1960s, the patient had a biopsy performed on one of the lesions (results are unknown) and received 1.5 years of UV-B phototherapy. Over the years, the patient sought treatment from other dermatologists, several of whom performed biopsies (results also References 1. Sarkany I, Fountain RB, Evans CD, et al. Multiple basal-cell epitheliomata following radiotherapy of the spine . Br J Dermatol. 1968;80:90-96.Crossref 2. Kellerer AM. Microdosimetry and its implication for the primary process in radiation carcinogenesis . In: Yuhas JM, Tennant RA, Regan JD, eds. Biology of Radiation Carcinogenesis . New York, NY: Raven Press; 1976:1-12. 3. Good AE, Diaz LA, Bowerman RA. Basal cell carcinomas following roentgen therapy of ankylosing spondylitis . Arthritis Rheum . 1980;23:1065-1066.Crossref 4. Rampling RP, Lambert HE. Multiple basal cell carcinomas in two cases of ankylosing spondylitis treated with x-ray therapy . Br J Radiol. 1985;58:178-181.Crossref 5. Allison JR Jr. Radiation-induced basal-cell carcinoma . J Dermatol Surg Oncol. 1984;10:200-203.Crossref
Archives of Dermatology – American Medical Association
Published: Apr 1, 1995
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