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Multicystic Dysplastic Kidneys

Multicystic Dysplastic Kidneys This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.—We appreciate Dr Bowen's letter calling out attention to the recent reports of prenatal US identification of MCDKs, as well as his thoughts regarding the natural history of these lesions. Although the number of prenatally identified lesions is small, it is interesting to note the high rate of decrease in size documented by the two reports.While decrease in size is understandable, it is hard to explain the complete resorption or dissolution of a dysplastic organ. While many of these kidneys may indeed decrease in size, it is not clear that a decrease in size is equivalent to a decrease in risk to the patient, specifically in regard to the development of hypertension or malignant change. It is clear that we have inadequate knowledge of the natural history of MCDK to make an unequivocal recommendation for either routine resection or nonoperative observation. Our dilemma revolves around a lack of such information and a documentation of potentially serious complications, such as hypertension and malignant lesions, in retained MCDKs. Since it is unclear whether the risk of these complications is greater in MCDK patients than in the general population, the only definitive statement that can be rendered is that if such lesions are left in place, careful monitoring on a regular basis for the development of such complications is incumbent on the primary physician. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Multicystic Dysplastic Kidneys

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.—We appreciate Dr Bowen's letter calling out attention to the recent reports of prenatal US identification of MCDKs, as well as his thoughts regarding the natural history of these lesions. Although the number of prenatally identified lesions is small, it is interesting to note the high rate of decrease in size documented by the two...
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Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1987.04460060020012
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.—We appreciate Dr Bowen's letter calling out attention to the recent reports of prenatal US identification of MCDKs, as well as his thoughts regarding the natural history of these lesions. Although the number of prenatally identified lesions is small, it is interesting to note the high rate of decrease in size documented by the two reports.While decrease in size is understandable, it is hard to explain the complete resorption or dissolution of a dysplastic organ. While many of these kidneys may indeed decrease in size, it is not clear that a decrease in size is equivalent to a decrease in risk to the patient, specifically in regard to the development of hypertension or malignant change. It is clear that we have inadequate knowledge of the natural history of MCDK to make an unequivocal recommendation for either routine resection or nonoperative observation. Our dilemma revolves around a lack of such information and a documentation of potentially serious complications, such as hypertension and malignant lesions, in retained MCDKs. Since it is unclear whether the risk of these complications is greater in MCDK patients than in the general population, the only definitive statement that can be rendered is that if such lesions are left in place, careful monitoring on a regular basis for the development of such complications is incumbent on the primary physician.

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jun 1, 1987

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