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Mounting Evidence of Paraben Sensitivity in Dogs

Mounting Evidence of Paraben Sensitivity in Dogs Abstract To the Editor.— I wish to bring to the attention of your readership a much neglected study done in 1979 by Goodwin et al.1 The authors chromatographed the volatile components of the vaginal secretions of female beagle dogs in an effort to identify specific pheromones. During estrus, when sexual receptivity was maximal, unique chromatographic peaks were noted. Concentration and analysis of these peaks revealed that methyl p-hydroxybenzoate was the main volatile component present. It was not present during proestrus or anestrus. The authors then applied pure methyl p-hydroxybenzoate to the vulva and in the vagina of anestrus females, and they sexually aroused and were mounted by males as though they were in estrus.Methyl p-hydroxybenzoate is, of course, better known to dermatologists as methylparaben, the common preservative in cosmetics and topical medications. Rover may not be oversexed at all. We may be inadvertently stimulating him with References 1. Goodwin M, Gooding KM, Regnier F: Sex pheromone in the dog . Science 1979; 203:559-561.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Mounting Evidence of Paraben Sensitivity in Dogs

Archives of Dermatology , Volume 121 (9) – Sep 1, 1985

Mounting Evidence of Paraben Sensitivity in Dogs

Abstract

Abstract To the Editor.— I wish to bring to the attention of your readership a much neglected study done in 1979 by Goodwin et al.1 The authors chromatographed the volatile components of the vaginal secretions of female beagle dogs in an effort to identify specific pheromones. During estrus, when sexual receptivity was maximal, unique chromatographic peaks were noted. Concentration and analysis of these peaks revealed that methyl p-hydroxybenzoate was the main volatile component...
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Publisher
American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1985.01660090021007
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— I wish to bring to the attention of your readership a much neglected study done in 1979 by Goodwin et al.1 The authors chromatographed the volatile components of the vaginal secretions of female beagle dogs in an effort to identify specific pheromones. During estrus, when sexual receptivity was maximal, unique chromatographic peaks were noted. Concentration and analysis of these peaks revealed that methyl p-hydroxybenzoate was the main volatile component present. It was not present during proestrus or anestrus. The authors then applied pure methyl p-hydroxybenzoate to the vulva and in the vagina of anestrus females, and they sexually aroused and were mounted by males as though they were in estrus.Methyl p-hydroxybenzoate is, of course, better known to dermatologists as methylparaben, the common preservative in cosmetics and topical medications. Rover may not be oversexed at all. We may be inadvertently stimulating him with References 1. Goodwin M, Gooding KM, Regnier F: Sex pheromone in the dog . Science 1979; 203:559-561.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Sep 1, 1985

References