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More on Adrenalectomy for Metastatic Breast Cancer

More on Adrenalectomy for Metastatic Breast Cancer Abstract To the Editor.—I am responding to the article by Brown et al, entitled "Bilateral Adrenalectomy for Metastatic Breast Carcinoma" (Arch Surg 110:77-81, 1975). Several of their findings were in agreement with our published results, as listed below: Sulfokinase activity in breast cancer tissue is not a good predictive index for adrenalectomy.1 Since our preliminary report, more than 56 patients have been evaluated; results were not encouraging. In evaluating 119 patients who had undergone adrenalectomy in our institution, we did not find any correlation of a tumor-free interval to subsequent response to adrenalectomy. Forty percent of the patients with tumor-free intervals of less than one year had responded to adrenalectomy, compared with 47% to 48% of patients with longer tumor-free intervals.1 However, other clinical criteria, such as age, menopausal status, and cytohormonal evaluation, are of minor importance in relationship to subsequent clinical response to adrenalectomy. It has References 1. Moseley HS, Fletcher WS, Leung BS, et al: Predictive criteria for the selection of breast cancer patients for adrenalectomy . Am J Surg 128:143-151, 1974.Crossref 2. Leung BS, Fletcher WS, Lindell TD, et al: Predictability of response to endocrine ablation in advanced breast carcinoma . Arch Surg 106:515-519, 1973.Crossref 3. Leung BS, Moseley HS, Davenport GE, et al: Estrogen receptors in prediction of clinical responses to endocrine ablation , in McGuire WL, Carbone PP, Vollmer EP (eds): Estrogen Receptors in Human Breast Cancer . New York, Raven Press, 1975, pp 107-129. 4. McGuire WL, Carbone PP, Vollmer EP: Estrogen Receptors in Human Breast Cancer . New York, Raven Press, 1975. 5. Sasaki GH, Leung BS, Fletcher WS: Levodopa test and estrogen receptor assay in prognosticating responses of patients with advanced cancer of the breast to endocrine therapy, abstract 31, in Proceedings of the 28th Annual Meeting of the James Ewing Society, 1975, pp 101-102. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

More on Adrenalectomy for Metastatic Breast Cancer

Archives of Surgery , Volume 110 (12) – Dec 1, 1975

More on Adrenalectomy for Metastatic Breast Cancer

Abstract

Abstract To the Editor.—I am responding to the article by Brown et al, entitled "Bilateral Adrenalectomy for Metastatic Breast Carcinoma" (Arch Surg 110:77-81, 1975). Several of their findings were in agreement with our published results, as listed below: Sulfokinase activity in breast cancer tissue is not a good predictive index for adrenalectomy.1 Since our preliminary report, more than 56 patients have been evaluated; results were not encouraging. In evaluating 119 patients...
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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1975.01360180087023
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.—I am responding to the article by Brown et al, entitled "Bilateral Adrenalectomy for Metastatic Breast Carcinoma" (Arch Surg 110:77-81, 1975). Several of their findings were in agreement with our published results, as listed below: Sulfokinase activity in breast cancer tissue is not a good predictive index for adrenalectomy.1 Since our preliminary report, more than 56 patients have been evaluated; results were not encouraging. In evaluating 119 patients who had undergone adrenalectomy in our institution, we did not find any correlation of a tumor-free interval to subsequent response to adrenalectomy. Forty percent of the patients with tumor-free intervals of less than one year had responded to adrenalectomy, compared with 47% to 48% of patients with longer tumor-free intervals.1 However, other clinical criteria, such as age, menopausal status, and cytohormonal evaluation, are of minor importance in relationship to subsequent clinical response to adrenalectomy. It has References 1. Moseley HS, Fletcher WS, Leung BS, et al: Predictive criteria for the selection of breast cancer patients for adrenalectomy . Am J Surg 128:143-151, 1974.Crossref 2. Leung BS, Fletcher WS, Lindell TD, et al: Predictability of response to endocrine ablation in advanced breast carcinoma . Arch Surg 106:515-519, 1973.Crossref 3. Leung BS, Moseley HS, Davenport GE, et al: Estrogen receptors in prediction of clinical responses to endocrine ablation , in McGuire WL, Carbone PP, Vollmer EP (eds): Estrogen Receptors in Human Breast Cancer . New York, Raven Press, 1975, pp 107-129. 4. McGuire WL, Carbone PP, Vollmer EP: Estrogen Receptors in Human Breast Cancer . New York, Raven Press, 1975. 5. Sasaki GH, Leung BS, Fletcher WS: Levodopa test and estrogen receptor assay in prognosticating responses of patients with advanced cancer of the breast to endocrine therapy, abstract 31, in Proceedings of the 28th Annual Meeting of the James Ewing Society, 1975, pp 101-102.

Journal

Archives of SurgeryAmerican Medical Association

Published: Dec 1, 1975

References