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Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing?

Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s... Opinion EDITORIAL Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing? Ralph M. Trüeb, MD Guard us against breast cancer and other afflictions of women, genetic alopecia-like, both clinically and on trichoscopic exami- and inspire us to overcome adversity. nation;negativeimpactonqualityoflifewassignificant;andtopi- From a prayer to St Agatha of Sicily, cal minoxidil improved alopecia in 80% of treated patients. Patron Saint for women Androgenetic alopecia is characterized by progressive short- with breast cancer ening of the duration of anagen with successive hair cycles, lead- ing to decreased numbers of hair in anagen at any given time, Worldwide, breast cancer is the most common invasive can- and progressive follicular miniaturization with conversion of ter- cer in women, affecting about 12%. The incidence has signifi- minal to vellus-like follicles. The result is increased shedding cantly increased since the 1970s; however, with the advances of short-lived telogen hairs, while the affected hair follicles pro- and sophistication in diagno- duce shorter, finer hairs that cover the scalp poorly. Although sis and treatment, survival androgens have dominated endocrinologic research into an- Related article page 670 rates have become high, with drogenetic alopecia, and androgen metabolism and the andro- between 80% and 90% of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing?

JAMA Dermatology , Volume 154 (6) – Jun 11, 2018

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Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/jamadermatol.2018.0453
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing? Ralph M. Trüeb, MD Guard us against breast cancer and other afflictions of women, genetic alopecia-like, both clinically and on trichoscopic exami- and inspire us to overcome adversity. nation;negativeimpactonqualityoflifewassignificant;andtopi- From a prayer to St Agatha of Sicily, cal minoxidil improved alopecia in 80% of treated patients. Patron Saint for women Androgenetic alopecia is characterized by progressive short- with breast cancer ening of the duration of anagen with successive hair cycles, lead- ing to decreased numbers of hair in anagen at any given time, Worldwide, breast cancer is the most common invasive can- and progressive follicular miniaturization with conversion of ter- cer in women, affecting about 12%. The incidence has signifi- minal to vellus-like follicles. The result is increased shedding cantly increased since the 1970s; however, with the advances of short-lived telogen hairs, while the affected hair follicles pro- and sophistication in diagno- duce shorter, finer hairs that cover the scalp poorly. Although sis and treatment, survival androgens have dominated endocrinologic research into an- Related article page 670 rates have become high, with drogenetic alopecia, and androgen metabolism and the andro- between 80% and 90% of

Journal

JAMA DermatologyAmerican Medical Association

Published: Jun 11, 2018

References