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MINERAL METABOLISM IN OSTEOGENESIS IMPERFECTA

MINERAL METABOLISM IN OSTEOGENESIS IMPERFECTA The knowledge of mineral metabolism in osteogenesis imperfecta has been obtained mainly from the investigations of Schwarz and Bass,1 Bookman,2 and Klercker3 and recently from a more detailed study by Sindler.4 A summary and comparison of their data with a study of the metabolism in a similar case are presented in this paper. Only by thus summarizing the data and by adding more complete analyses will an approach to the study of this baffling disease yield its store of information. No attempt has been made to review the clinical and pathologic literature on the subject since this has been done recently by Dietrich.5 We were fortunate in being able to study soon after birth a female infant who showed all the clinical signs of osteogenesis imperfecta. The clinical diagnosis was further verified by the roentgenogram, as shown in the figure. REPORT OF A CASE The http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

MINERAL METABOLISM IN OSTEOGENESIS IMPERFECTA

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Publisher
American Medical Association
Copyright
Copyright © 1935 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1935.01970040126016
Publisher site
See Article on Publisher Site

Abstract

The knowledge of mineral metabolism in osteogenesis imperfecta has been obtained mainly from the investigations of Schwarz and Bass,1 Bookman,2 and Klercker3 and recently from a more detailed study by Sindler.4 A summary and comparison of their data with a study of the metabolism in a similar case are presented in this paper. Only by thus summarizing the data and by adding more complete analyses will an approach to the study of this baffling disease yield its store of information. No attempt has been made to review the clinical and pathologic literature on the subject since this has been done recently by Dietrich.5 We were fortunate in being able to study soon after birth a female infant who showed all the clinical signs of osteogenesis imperfecta. The clinical diagnosis was further verified by the roentgenogram, as shown in the figure. REPORT OF A CASE The

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Apr 1, 1935

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