Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Mima Polymorpha Meningitis: Report of Case and Review of the Literature

Mima Polymorpha Meningitis: Report of Case and Review of the Literature Abstract The micro-organism Mima polymorpha was first isolated in 1939 by DeBord1 from the urethral discharge of patients being studied for resistant gonorrhea. This Gramnegative rod, with a marked tendency to pleomorphism, was aptly named by him because of its ability to mimic other Gramnegative bacteria, particularly those of the Neisseria genus. M. polymorpha remained primarily the interest of the bacteriologist until 1948, at which time DeBord2 reported a case of meningitis in which this microorganism was identified in the cerebrospinal fluid. Since then there have been five reported cases of meningitis due to M. polymorpha,3-6 but only one of these occurred in a patient of the pediatric age group.3 The purpose of this case report is to call the attention of those caring for children to this micro-organism as an etiologic agent in meningitis, emphasizing its ability to mimic other infections and the variability of findings References 1. DeBord, G. G.: Organisms Invalidating the Diagnosis of Gonorrhea by Smear Method , J. Bact. 38:119-121 ( (July) ) 1939. 2. DeBord, G. G.: Mima Polymorpha in Meningitis , J. Bact. 55:764-765 ( (May) ) 1948. 3. Schuldberg, I. I.: Clinical and Pathological Simulation of Meningococcic Meningitis: Report of Case with Necropsy , Am. J. Clin. Path. 23: 1024-1027 ( (Oct.) ) 1953. 4. Townsend, F. M.; Hersey, D. F., and Wilson, F. W.: Mima Polymorpha as a Causative Agent in Waterhouse-Friderichsen Syndrome , U. S. Armed Forces M. J. 5:673-679 ( (May) ) 1954. 5. Olafsson, M.; Lee, Y. C., and Abernathy, T. J.: Mima Polymorpha Meningitis , New England J. Med. 258:465-470 ( (March 6) ) 1958.Crossref 6. Fred, H. L.; Allen, T. D.; Hassel, H. L., and Holtzman, C. F.: Meningitis Due to Mima Polymorpha , A.M.A. Arch. Int. Med. 102:204-206 ( (Aug.) ) 1958.Crossref 7. Breed, R. S.; Murray, E. G. D., and Hitchens, A. P.: Bergey's Manual of Determinative Bacteriology , Ed. 6, Baltimore, The Williams & Wilkins Company, 1948. 8. Brooks, B. E., and Sanders, A. C.: "Unidentified" Gram Negative Rods and the Tribe Mimeae , U. S. Armed Forces M. J. , 5:667-672 ( (May) ) 1954. 9. Cary, S. G.; Lindberg, R. B., and Faber, J. E., Jr.: Typing of Mima Polymorpha by the Precipitin Technique , J. Bact. 72:728-729 ( (Dec.) ) 1956. 10. Alexander, H. E.: Advances in the Treatment of Bacterial Meningitis , Advances Pediat. 5:13-52 ( (Jan.) ) 1952. 11. Lepper, M. H.; Blatt, N. H.; Wehrle, P. F., and Spies, H. W.: Treatment of Bacterial Meningitis of Unusual Etiology and Purulent Meningitis of Unknown Origin , A. M. A. Am. J. Dis. Child. 85:295-302 ( (March) ) 1953. 12. Smith, E.: Purulent Meningitis in Infants and Children: A Review of 409 Cases , J. Pediat. 45:425-436 ( (Oct.) ) 1954.Crossref 13. Severy, W. L.: Meningitis: A Review of the Year's Cases from an Active Children's Hospital Service , California Med. 82:436-439 ( (June) ) 1955. 14. Smith, M. H. D.: Acute Bacterial Meningitis , Pediatrics 17:258-277 ( (Feb.) ) 1956. 15. Carson, M. J. and Koch, R.: Management of Bacterial Meningitis in Children , Pediat. Clin. North America , pp. 377-398 ( (May) ) 1956. 16. Cavanaugh, J. J. A., and Kline, A. H.: Review of Bacterial Meningitis in Children at the Harriet Lane Home, Johns Hopkins Hospital, unpublished data. 17. Daniels, W. B.; Solomon, S., and Jaquette, W. A. Jr.: Meningococcal Infection in Soldiers , J.A.M.A. 123:1-9 ( (Sept. 4) ) 1943.Crossref 18. Faust, J., and Hood, M.: Fulminating Septicemia Caused by Mima Polymorpha: Report of Case , Am. J. Clin. Path. 19:1143-1145 ( (Dec.) ) 1949. 19. Pike, R. M.; Schulze, M. L., and McCullough, M.: Isolation of Mima Polymorpha from Patient with Subacute Bacterial Endocarditis , Am. J. Clin. Path. 21:1094-1096 ( (Nov.) ) 1951. 20. Bansmer, C., and Brem, J.: Acute Meningitis Caused by Neisseria Sicca , New England J. Med. 238:596-597 ( (April 22) ) 1948.Crossref 21. Brainerd, H., and Bradley, E.: Treatment of Bacterial Meningitis with Penicillin and Sulfonamides , California Med. 66:57-62, ( (Feb.) ) 1947. 22. Branham, S. E.: A New Meningococcus Organism, (Neisseria flavescens) Pub. Health Rep. 45:845-849 ( (Aug.) ) 1930.Crossref 23. Branham, S. E.; Mitchell, R. H., and Brainin, W.: Gonococcic Meningitis , J. A. M. A. 110:1804-1806 ( (May 28) ) 1938.Crossref 24. Corfield, W. F.: Multiple Attacks of Cerebrospinal Fever , Lancet 1:402-403 ( (March 31) ) 1945.Crossref 25. Daeschner, C. W.; Clark, J. L.; Yow, E. M., and Townsend, E.: Comparative Evaluation of the Sulfonamides , J. Pediat. 50:531-551 ( (May) ) 1957.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Journal of Diseases of Children American Medical Association

Mima Polymorpha Meningitis: Report of Case and Review of the Literature

Loading next page...
 
/lp/american-medical-association/mima-polymorpha-meningitis-report-of-case-and-review-of-the-literature-gh7Ct26NaZ
Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-6916
DOI
10.1001/archpedi.1959.02070020381012
Publisher site
See Article on Publisher Site

Abstract

Abstract The micro-organism Mima polymorpha was first isolated in 1939 by DeBord1 from the urethral discharge of patients being studied for resistant gonorrhea. This Gramnegative rod, with a marked tendency to pleomorphism, was aptly named by him because of its ability to mimic other Gramnegative bacteria, particularly those of the Neisseria genus. M. polymorpha remained primarily the interest of the bacteriologist until 1948, at which time DeBord2 reported a case of meningitis in which this microorganism was identified in the cerebrospinal fluid. Since then there have been five reported cases of meningitis due to M. polymorpha,3-6 but only one of these occurred in a patient of the pediatric age group.3 The purpose of this case report is to call the attention of those caring for children to this micro-organism as an etiologic agent in meningitis, emphasizing its ability to mimic other infections and the variability of findings References 1. DeBord, G. G.: Organisms Invalidating the Diagnosis of Gonorrhea by Smear Method , J. Bact. 38:119-121 ( (July) ) 1939. 2. DeBord, G. G.: Mima Polymorpha in Meningitis , J. Bact. 55:764-765 ( (May) ) 1948. 3. Schuldberg, I. I.: Clinical and Pathological Simulation of Meningococcic Meningitis: Report of Case with Necropsy , Am. J. Clin. Path. 23: 1024-1027 ( (Oct.) ) 1953. 4. Townsend, F. M.; Hersey, D. F., and Wilson, F. W.: Mima Polymorpha as a Causative Agent in Waterhouse-Friderichsen Syndrome , U. S. Armed Forces M. J. 5:673-679 ( (May) ) 1954. 5. Olafsson, M.; Lee, Y. C., and Abernathy, T. J.: Mima Polymorpha Meningitis , New England J. Med. 258:465-470 ( (March 6) ) 1958.Crossref 6. Fred, H. L.; Allen, T. D.; Hassel, H. L., and Holtzman, C. F.: Meningitis Due to Mima Polymorpha , A.M.A. Arch. Int. Med. 102:204-206 ( (Aug.) ) 1958.Crossref 7. Breed, R. S.; Murray, E. G. D., and Hitchens, A. P.: Bergey's Manual of Determinative Bacteriology , Ed. 6, Baltimore, The Williams & Wilkins Company, 1948. 8. Brooks, B. E., and Sanders, A. C.: "Unidentified" Gram Negative Rods and the Tribe Mimeae , U. S. Armed Forces M. J. , 5:667-672 ( (May) ) 1954. 9. Cary, S. G.; Lindberg, R. B., and Faber, J. E., Jr.: Typing of Mima Polymorpha by the Precipitin Technique , J. Bact. 72:728-729 ( (Dec.) ) 1956. 10. Alexander, H. E.: Advances in the Treatment of Bacterial Meningitis , Advances Pediat. 5:13-52 ( (Jan.) ) 1952. 11. Lepper, M. H.; Blatt, N. H.; Wehrle, P. F., and Spies, H. W.: Treatment of Bacterial Meningitis of Unusual Etiology and Purulent Meningitis of Unknown Origin , A. M. A. Am. J. Dis. Child. 85:295-302 ( (March) ) 1953. 12. Smith, E.: Purulent Meningitis in Infants and Children: A Review of 409 Cases , J. Pediat. 45:425-436 ( (Oct.) ) 1954.Crossref 13. Severy, W. L.: Meningitis: A Review of the Year's Cases from an Active Children's Hospital Service , California Med. 82:436-439 ( (June) ) 1955. 14. Smith, M. H. D.: Acute Bacterial Meningitis , Pediatrics 17:258-277 ( (Feb.) ) 1956. 15. Carson, M. J. and Koch, R.: Management of Bacterial Meningitis in Children , Pediat. Clin. North America , pp. 377-398 ( (May) ) 1956. 16. Cavanaugh, J. J. A., and Kline, A. H.: Review of Bacterial Meningitis in Children at the Harriet Lane Home, Johns Hopkins Hospital, unpublished data. 17. Daniels, W. B.; Solomon, S., and Jaquette, W. A. Jr.: Meningococcal Infection in Soldiers , J.A.M.A. 123:1-9 ( (Sept. 4) ) 1943.Crossref 18. Faust, J., and Hood, M.: Fulminating Septicemia Caused by Mima Polymorpha: Report of Case , Am. J. Clin. Path. 19:1143-1145 ( (Dec.) ) 1949. 19. Pike, R. M.; Schulze, M. L., and McCullough, M.: Isolation of Mima Polymorpha from Patient with Subacute Bacterial Endocarditis , Am. J. Clin. Path. 21:1094-1096 ( (Nov.) ) 1951. 20. Bansmer, C., and Brem, J.: Acute Meningitis Caused by Neisseria Sicca , New England J. Med. 238:596-597 ( (April 22) ) 1948.Crossref 21. Brainerd, H., and Bradley, E.: Treatment of Bacterial Meningitis with Penicillin and Sulfonamides , California Med. 66:57-62, ( (Feb.) ) 1947. 22. Branham, S. E.: A New Meningococcus Organism, (Neisseria flavescens) Pub. Health Rep. 45:845-849 ( (Aug.) ) 1930.Crossref 23. Branham, S. E.; Mitchell, R. H., and Brainin, W.: Gonococcic Meningitis , J. A. M. A. 110:1804-1806 ( (May 28) ) 1938.Crossref 24. Corfield, W. F.: Multiple Attacks of Cerebrospinal Fever , Lancet 1:402-403 ( (March 31) ) 1945.Crossref 25. Daeschner, C. W.; Clark, J. L.; Yow, E. M., and Townsend, E.: Comparative Evaluation of the Sulfonamides , J. Pediat. 50:531-551 ( (May) ) 1957.Crossref

Journal

A.M.A. Journal of Diseases of ChildrenAmerican Medical Association

Published: Sep 1, 1959

References