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METABOLIC MANAGEMENT OF ADVANCED PROSTATIC CANCER

METABOLIC MANAGEMENT OF ADVANCED PROSTATIC CANCER Abstract THIS YEAR marks the 10th anniversary of the inception of the treatment of prostatic cancer by means of the administration of certain estrogenic-like substances, on the one hand, and castration, on the other. Contributions in this field have been many and most valuable, not only in the field of prostatic cancer alone but in the much broader field of the chemical aspects of cancer in general. From all these many contributions and observations has evolved what appears to be a fairly reasonable and rational plan of management. This plan is as follows: First of all, there is no controversy as to whether prostatic cancer should be removed surgically. Our main problem in surgical indications at the present time involves chiefly the extent to which one chooses to perform surgery. It will be quite some time, unfortunately, before an appraisal of end-results will make it possible to determine how radical surgery References 1. Colston, J. A. C., and Brendler, H.: Endocrine Therapy in Carcinoma of Prostate: Preparation of Patients for Radical Perineal Prostatectomy , J. A. M. A. 134:848-853, 1947.Crossref 2. Munger, A. D.: Experience in Treatment of Carcinoma of the Prostate with Irradiation of the Testicles , J. Urol. 46:1007-1011, 1941. 3. Brendler, H.; Chase, W. E., and Scott, W. W.: Prostatic Cancer: Further Investigation of Hormonal Relationships , Arch. Surg. 61:433-440, 1950.Crossref 4. Huggins, C., and Scott, W. W.: Bilateral Adrenalectomy in Prostatic Cancer , Ann. Surg. 122:1031-1041, 1945.Crossref 5. Oelbaum, M. H.: Medical Aspects of Carcinoma of the Prostate with Secondary Deposits in the Bone , Lancet 1:811-813, 1950.Crossref 6. Kearns, W. M.: Treatment of Carcinoma of the Prostate with Estrogens , Wisconsin M. J. 41:575-581, 1942. 7. Lieberman, S., and Dobriner, K.: Steroid Hormones , Madison, Wis., University of Wisconsin Press, 1950. 8. May, J. A.: Estrogen Excretion Studies in Patients with Carcinoma of the Prostate Gland, Urology, Correspondence Club Letters, Dec. 15, 1947. 9. Nesbit, R. M., and others: Endocrine Control of Prostatic Carcinoma: Clinical and Statistical Study of 1818 Cases , J. A. M. A. 243:1317-1320, 1950.Crossref 10. Cromer, K.: Personal communication to the author. 11. Mulry, W. C., and Dudley, H. C.: Studies of Radio Gallium as a Diagnostic Agent in Bone Tumors , J. Lab. & Clin. Med. 37:239-252, 1951. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives Surgery American Medical Association

METABOLIC MANAGEMENT OF ADVANCED PROSTATIC CANCER

A.M.A. Archives Surgery , Volume 64 (6) – Jun 1, 1952

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Publisher
American Medical Association
Copyright
Copyright © 1952 American Medical Association. All Rights Reserved.
ISSN
0096-6908
DOI
10.1001/archsurg.1952.01260010848014
Publisher site
See Article on Publisher Site

Abstract

Abstract THIS YEAR marks the 10th anniversary of the inception of the treatment of prostatic cancer by means of the administration of certain estrogenic-like substances, on the one hand, and castration, on the other. Contributions in this field have been many and most valuable, not only in the field of prostatic cancer alone but in the much broader field of the chemical aspects of cancer in general. From all these many contributions and observations has evolved what appears to be a fairly reasonable and rational plan of management. This plan is as follows: First of all, there is no controversy as to whether prostatic cancer should be removed surgically. Our main problem in surgical indications at the present time involves chiefly the extent to which one chooses to perform surgery. It will be quite some time, unfortunately, before an appraisal of end-results will make it possible to determine how radical surgery References 1. Colston, J. A. C., and Brendler, H.: Endocrine Therapy in Carcinoma of Prostate: Preparation of Patients for Radical Perineal Prostatectomy , J. A. M. A. 134:848-853, 1947.Crossref 2. Munger, A. D.: Experience in Treatment of Carcinoma of the Prostate with Irradiation of the Testicles , J. Urol. 46:1007-1011, 1941. 3. Brendler, H.; Chase, W. E., and Scott, W. W.: Prostatic Cancer: Further Investigation of Hormonal Relationships , Arch. Surg. 61:433-440, 1950.Crossref 4. Huggins, C., and Scott, W. W.: Bilateral Adrenalectomy in Prostatic Cancer , Ann. Surg. 122:1031-1041, 1945.Crossref 5. Oelbaum, M. H.: Medical Aspects of Carcinoma of the Prostate with Secondary Deposits in the Bone , Lancet 1:811-813, 1950.Crossref 6. Kearns, W. M.: Treatment of Carcinoma of the Prostate with Estrogens , Wisconsin M. J. 41:575-581, 1942. 7. Lieberman, S., and Dobriner, K.: Steroid Hormones , Madison, Wis., University of Wisconsin Press, 1950. 8. May, J. A.: Estrogen Excretion Studies in Patients with Carcinoma of the Prostate Gland, Urology, Correspondence Club Letters, Dec. 15, 1947. 9. Nesbit, R. M., and others: Endocrine Control of Prostatic Carcinoma: Clinical and Statistical Study of 1818 Cases , J. A. M. A. 243:1317-1320, 1950.Crossref 10. Cromer, K.: Personal communication to the author. 11. Mulry, W. C., and Dudley, H. C.: Studies of Radio Gallium as a Diagnostic Agent in Bone Tumors , J. Lab. & Clin. Med. 37:239-252, 1951.

Journal

A.M.A. Archives SurgeryAmerican Medical Association

Published: Jun 1, 1952

References